Dripping pills for treating rhinitis and its preparing process

A technology of Huodan and rhinitis, which is applied in the field of Huodanbiyan dropping pills and its preparation, can solve the problems of long dissolution time, low dissolution rate, and unfavorable improvement of patients' ability to seek medical treatment, so as to avoid gastrointestinal irritation symptoms, dissolve And the effect of accelerated absorption and improved bioavailability

Inactive Publication Date: 2005-07-06
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Huodanbiyan Capsules are currently available, and there is no other similar dosage form on the market
[0013] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also give some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Now with several groups of specific examples, the preparation method of Huodanbiyan dropping pills of the present invention will be further described.

[0041] Group 1: Tests with a single matrix

[0042] 1. Weigh a certain amount of main ingredients according to the ratio given in [Preparation Method] 1. Preparation method] made. spare;

[0043] 2. Substrate: polyethylene glycol (1000~20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0044] 3. Proportion—in g or kg, by weight, main ingredient: matrix = 1:1~1:9;

[0045] 4. Then prepare according to the process of [Preparation Method] 4-7, that is, Huodan Biyan Dropping Pills of various specifications can be prepared.

[0046] [test results]

[0047] Experiment 1: In order to observe the difference in quality of the Huodanbiyan Dropping Pills prepared when the mai...

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PUM

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Abstract

The invention discloses a dripping pills for treating rhinitis and its preparing process having the functions of wind dispelling, venting nasal tube and treating chronic rhinitis and anaphylactic rhinitis, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, and low price.

Description

technical field [0001] The present invention relates to a kind of medicinal composition which has the effect of clearing away wind and heat and dredging nasal orifices, and is used for treating symptoms such as chronic rhinitis, chronic paranasal sinusitis and allergic rhinitis. A medicine composition oral drop pill preparation obtained by reforming the dosage form. Background technique [0002] According to the ministerial standard WS 3 -Huodan rhinitis capsule prepared by the formula and extraction process given in B-2822-97 is a kind of capsule with clearing wind and heat, clearing the nose; used for the treatment of chronic rhinitis, chronic paranasal sinusitis and allergic rhinitis The tablet-like preparation has been clinically verified for many years, with stable quality and definite curative effect. It is a commonly used pharmaceutical preparation for clinical and family use to treat the above diseases. [0003] The following is the Ministry of Standards WS 3 -The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K35/413A61P11/02
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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