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Gynecoiatry leukorrhea stopping capsule and its preparation technology

A preparation process and capsule technology are applied in the field of traditional Chinese medicine capsules and their preparation to achieve the effects of fast onset, good economic benefits and short disintegration time

Active Publication Date: 2005-08-10
湖南天济草堂制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, it is still unknown to Chinese medicine workers whether the changed dosage form and process are suitable for industrial production

Method used

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  • Gynecoiatry leukorrhea stopping capsule and its preparation technology
  • Gynecoiatry leukorrhea stopping capsule and its preparation technology
  • Gynecoiatry leukorrhea stopping capsule and its preparation technology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0147] Take 363g of toon bark, 64g of schisandra, 363g of Phellodendron cortex, 242g of tortoise shell, 363g of Poria cocos, 120g of donkey-hide gelatin, and 363g of yam.

[0148] A. Toon skin is decocted twice, each time for 2 hours, add 8 times the amount of water for the first time, add 7 times the amount of water for the second time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.15, add Ethanol makes the alcohol content 50%, let it stand for 12 hours, and filter. B. Add 85% ethanol to Phellodendron Phellodendri and extract three times under reflux, 1.5 hours each time, add 7 times the amount for the first time, add 6 times the amount for the second time, and 6 times the amount for the third time, combine the extracts, and filter. C. Poria cocos is percolated with 60% ethanol, Schisandra chinensis and yam 45% ethanol, the flow rate is 5ml / min, and the amount of percolation liquid collected is 10 times the amount of raw material drug....

Embodiment 2-4

[0150] The steps of three batches of pilot test products are the same as in Example 1.

[0151] In order to verify and perfect the preparation process researched in the experiment, in order to achieve the operability of production and the adaptability to related equipment, we magnify the preparation prescription by 10 times and use the multi-functional extraction tank, vacuum concentration and drying equipment in the pilot plant. . Three batches of pilot-scale research were carried out on the best technological conditions obtained through laboratory research, and each key technical parameter was recorded in detail. And three batches of pilot products were tested for quality, the results are shown in Table 14.

[0152]

[0153] The above results show that the preparation process conditions of Fukezhidai Capsules are reasonable and feasible; the methods of extraction, concentration and drying are compatible with the scale-up production equipment; the quality of the ...

Embodiment 5

[0155] Other steps are the same as in Example 1, wherein 35 grams of auxiliary materials dextrin and 35 grams of starch are added to make 1000 grains, dried and pulverized, and filled with No. 0 capsules.

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PUM

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Abstract

A medicine for treating leukorrhagia is composed of the active component and the auxiliary which is starch and / or dextrin. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine capsule used for gynecological diseases and a preparation method thereof. Background technique [0002] Fuke Zhidai Tablet is a traditional Chinese medicine preparation widely used in clinical practice and has certain curative effect for the treatment of damp-heat red leucorrhea caused by chronic cervicitis, endometritis and vaginal mucositis. However, this traditional Chinese medicine preparation belongs to tablets, and patients feel bitter when taking it, and often find it difficult to swallow, and the disintegration time is long, which is not conducive to the rapid dissolution of active ingredients and slow onset of effect. Its single-tablet dosage form also leaves physicians and patients with little choice. And the original preparation method is: Chinese toon skin is decocted twice with water, each time for 2 hours, the decoction is combined, filtered, the filtrate is concentrated to an appro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K35/36A61K35/586A61P15/00
Inventor 翁小涛
Owner 湖南天济草堂制药股份有限公司
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