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Effervescence tablet for treating wind-cold type cold and preparation process thereof

A technology for clearing heat and effervescent tablets for colds, which can be used in antipyretics, pharmaceutical formulations, anti-infectives, etc., and can solve the problems of poor stability, slow disintegration, and difficulty in forming Chinese medicine effervescent tablets.

Active Publication Date: 2006-02-15
BEIJING TONGRENTANG HEALTH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problems of difficult molding, slow disintegration, poor clarity, and poor stability of traditional Chinese medicine effervescent tablets, the present invention provides a kind of main drug and auxiliary materials with reasonable proportions, good molding, and good stability. its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0040] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0041] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0042] Reed root 1200g

[0043] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0044] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

Embodiment 2

[0047] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0048] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0049] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0050] Reed root 1200g

[0051] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0052](2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fil...

Embodiment 3

[0055] According to the share of each raw material in Ganmao Qingre Effervescent Tablets, take the following prescription raw materials (in grams) for subsequent use:

[0056] Nepeta ear 1500g Mint 450g Fangfeng 750g Bupleurum 750g Perilla leaf 450g

[0057] Pueraria root 750g Bellflower 450g Bitter almond 600g Angelica dahurica 450g Kudiding 1500g

[0058] Reed root 1200g

[0059] (1) Take Nepeta chinensis, mint, perilla leaves, add 10 times the amount of water, soak for 2 hours, steam distill for 6 hours to extract the volatile oil, collect the distilled aqueous solution in another device, and use the dregs for later use; Essence-water 1:8:80 inclusion volatile oil, stirred at 50°C for 1 hour, refrigerated overnight, filtered, dried at 40°C, and pulverized into fine powder to obtain beta-cyclodextrin inclusion complex.

[0060] (2) Add 12 times the amount of water to the dregs and other Bawei such as Fangfeng, decoct twice for 1.5 hours each time, combine the decoction, fi...

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Abstract

The invention relates to an effervescent tablet for treating wind-cold type cold and preparation process, wherein the effervescent tablet comprises concrete powder for reducing cold and fever, beta-cyclodextrin inclusion, acid agent, alkaline agent, sweetener, bulking agent, lubricating agent.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and more specifically relates to a Ganmao Qingre effervescent tablet and a preparation method thereof. Background technique [0002] The original preparation Ganmao Qingre Granule has the functions of dispelling wind and cold, relieving exterior and clearing heat. It is used for the treatment of wind-cold cold, headache and fever, aversion to cold and body pain, runny nose, cough and dry throat, and the effect is exact. But its preparation volume is bigger, and it is inconvenient to carry, and mouthfeel is bad. However, after the medicine is changed to Ganmaoqingre effervescent tablet, compared with granules, the volume is small, and it can be taken directly after the effervescence dissolves. [0003] Ganmao Qingre Effervescent Tablets are effervescent tablets made by reforming the dosage form of Ganmao Qingre Granules. Oral effervescent tablet is a new type of immediate-rel...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K9/20A61K9/46A61P29/00A61P31/00A61P11/00
Inventor 张保献
Owner BEIJING TONGRENTANG HEALTH PHARMA
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