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Pump system and method for transferring hyperpolarized gases

A hyperpolarization and gas technology, applied in control/regulation systems, pumps with flexible working elements, pumps, etc., can solve problems such as high polarization and loss

Inactive Publication Date: 2006-02-22
MEDI PHYSICS IN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is known that the use of commercially available pumps (e.g. diaphragm pumps) results in unacceptably high polarization losses

Method used

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  • Pump system and method for transferring hyperpolarized gases
  • Pump system and method for transferring hyperpolarized gases
  • Pump system and method for transferring hyperpolarized gases

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Embodiment Construction

[0023] As shown in FIG. 1 , the present invention provides a pump system 10 having an elongated hollow fluid line 12 defining an inlet port 14, an outlet port 16 and extending therebetween for delivery therethrough. Extended passage 18 for hyperpolarized gas. A first inlet valve 20 and a first outlet valve 22 are spaced apart within the fluid line 12 to provide interruptible and directable flow therethrough. System 10 includes a first pump chamber 24 defining an interior cavity 26 . A collapsible bladder 28 is secured within cavity 26 to define a gas cavity 30 in fluid communication with passage 18 of fluid line 12 at a location between inlet and outlet valves 20 and 22 . The balloon 28 includes a bladder wall 32 that also defines a cavity 26 to include a first fluid cavity 34 outside the bladder wall 32 and a gas cavity 30 inside the bladder wall 32 .

[0024] The pump system 10 also includes a fluid reservoir 36 defining a second fluid cavity 38 . The suction mechanism 40...

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Abstract

A pumping system for hyperpolarized gases employs a reversible fluid flow against a deflectable gas transport bladder (28). Inflation and deflation of the gas transport bladder (28) is operably associated with valves (20, 22) for directing the flow of the hyperpolarized gas. A second gas transport bladder (129) may be operably associated with additional valving (121, 123) so as to provide more continuous hyperpolarized gas flow. The first and second gas transport bladders may be arranged in-line with a reversible pumping mechanism (40, 140).

Description

technical field [0001] The present invention relates to the field of hyperpolarized gases. More specifically, the present invention relates to pump systems and methods for handling hyperpolarized gases. [0002] related application [0003] This application claims priority to U.S. Provisional Patent Application No. 60 / 440,747, filed January 17, 2003, and also claims priority to U.S. Provisional Patent Application No. 60 / 484,460, filed July 2, 2003, The entire disclosures of all of these patent applications are hereby incorporated by reference as if fully disclosed herein. Background technique [0004] For imaging and spectroscopy applications, applications like 129 Xe and 3 The use of hyperpolarized noble gases such as He is becoming more widespread. Hyperpolarized gases are particularly useful contrast agents for magnetic resonance imaging of body cavities. Each of these applications requires some amount of gas handling once the gas is polarized. It has been seen tha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/28F04B43/00F04B37/10F04B17/00F04B43/06F04B45/04F04B45/053F04B45/06
CPCA61K33/00F04B43/06F04B45/061F04B45/043F04B17/00G01R33/282F04B45/053G01R33/28
Inventor I·内尔逊S·卡德莱塞克J·诺尔斯
Owner MEDI PHYSICS IN