Compound preparation of multi-metalloidlothioneins and intrinsic biological active matter of earthworm

A thioprotein and polymetallic technology, which can be used in medical preparations containing active ingredients, peptide/protein ingredients, food preparation, etc. question

Inactive Publication Date: 2006-04-19
庄力枫
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  • Summary
  • Abstract
  • Description
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Problems solved by technology

There are many limitations such as long feeding period, uneven fluctuation of trace elements; large protein molecular weight; harmful hea

Method used

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Examples

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Embodiment Construction

[0025] According to the method of the present invention, it is described as follows in conjunction with the examples:

[0026] Artificial induction:

[0027] (1) First prepare the aqueous solution of trace elements, the concentration of each trace element solution is as follows: Cr4.8g / L, Mn5.6g / L, Zn11.6g / L, Se3.6g / L

[0028] (2) ground dragon induces bait, adds in the aged plant rotting material with sweet potato paste;

[0029] (3) trace element solution addition amount, add 50ml solution by every kilogram of bait, each trace element is a component, induces respectively;

[0030] (4) Induction program: induction-dormant-induction-dormant. Firstly, fresh and robust earthworms were introduced into the induction bed, fed with a daily amount of bait, followed by three stimulations and adjustments: temperature stimulation, from room temperature to 6°C for 8 hours, gradually increasing the temperature to 34°C, maintaining it for 8 hours, and cooling Heating each 4h. Dry and w...

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Abstract

A composite medicine used also as the additive of cosmetics and health-care food for lowering blood viscosity, dissolving thrombus, and regulating blood pressure, blood sugar and blood fat is prepared through extracting to obtain L-polybasic metallothionein (L.pMT), lumbrikinase and antibacterial peptide, proportionally mixing it with the extracts of astragalus root and red sage root, thiooctanoic acid and 1,6-pectose-zinc biphosphate, and dispensing.

Description

Technical field [0001] The present invention adopts a new type of biological carrier - Earthworm, uses physical and chemical induction methods to produce polymetallothionein-like and inherent biological actives of Earthworm - lumbrokinase, antibacterial peptide and other extracts of Earthworm, and compound Astragalus Extract, Danshen extract, lipoic acid and zinc 1,6 diphosphate fructose and other functional ingredients are used as medicines, health products and cosmetic additives. Background technique [0002] Earthworm has been used as a traditional Chinese medicine for thousands of years. It has the functions of promoting blood circulation and removing blood stasis, relieving asthma and relieving cough. Modern studies have found that Earthworm contains biological components such as lumbrokinase, antimicrobial peptides, purine and succinic acid, and collect Earthworm extract or Earthworm powder as pharmaceutical ingredients. Patent application number...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K38/48A61P7/02A61P3/10A61P3/06A61P9/12A23L1/305C12N9/64C07K14/435A23L33/17
Inventor 陶芒庄力枫
Owner 庄力枫
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