Gas-phase molecular ion reactor based on radio-frequency quard-polar rod, its realization and use

An ion reactor and radio frequency quadrupole technology, applied in the field of tandem mass spectrometry, can solve problems such as the difficulty of spectrum resolution, and achieve the effect of good controllability and high sensitivity
CN1779457AActive Publication Date: 2006-05-31KUSN HEXIN MASS PECTRUM TECH +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KUSN HEXIN MASS PECTRUM TECH
Publication Date
2006-05-31

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Abstract

A method for realizing gas phase molecule ¿C ion reaction based on radio frequency quadrupole rod includes imposing electric field on said quadrupole rod to let ion analyzed obtain kinetic energy and to let it generate molecule ¿C ion reaction with background gas molecule to generate subion of ion to be analyzed, using mass analyzer to measure subion for realizing cascade mass spectrum analysis of ion to be analyzed. A device of gas phase molecule ¿C ion reactor based on radio frequency quadrupole rod is also disclosed.
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Description

technical field

[0001] The invention relates to molecular ion reaction technology used in the field of tandem mass spectrometry, in particular to a gas phase molecular ion reactor device based on a radio frequency quadrupole and its realization method and application. Background technique

[0002] In the field of mass spectrometry, in order to analyze the lower content components in mixed samples, it is necessary to remove the background ions of high concentration components, and ion filtration technology is needed at this time. At the same time, as the molecular weight of the sample to be analyzed increases, isomers are very common, and the structural information of the molecule is becoming more and more important, such as the amino acid sequence of proteins and polypeptides, the structure of drugs, and the metabolites of drugs in the human body. The adducting position in DNA, the adducting position of toxic pollutants in DNA fragments, DNA base seq...

Claims

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