The application discloses an
ion mobility separation transmission device and an
ion transmission method, which comprise a focusing guide rod, a guide rod support, a mobility separation
electrode sheet, a partition, a focusing
electrode sheet, a first circuit board and a second connecting circuit board. The ions to be measured enter the mobility separation part of the
ion mobility separation transmission device, and are subjected to
electric field force and gas collision force. The ion
separation method operates in a pipeline mode. In the first period, the ions enter the device, spatial arrangement is generated according to the collision cross section size, and the ions are enriched. In the second period, a reverse
voltage is applied on the
atmospheric pressure interface air curtain disc to prevent subsequent ions from entering the device. The application adds the dimension information of the collision cross section, the ions can be enriched in the ion mobility separation transmission device, the ions are always bound by the
radio frequency quadrupole field in the channel from entering the ion mobility separation transmission device, are not easy to be lost, and the detection sensitivity can be improved.