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Stomatocace-treating medicine and its preparation method

A technology for oral ulcers and medicines, which is applied in the field of medicines for treating oral ulcers and their preparation, can solve the problems of waste, unacceptable for patients, and insufficient efficacy of medicines, and achieves the effects of accurate measurement, convenient use and better effect.

Inactive Publication Date: 2006-07-19
浙江南洋药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many inconveniences in the clinical application of ice boron membrane powder: (1) others need to blow over the affected area; (2) the dosage is difficult to control, which is easy to cause waste; (3) the medicine dissolves quickly in saliva and enters the digestive tract, Make the drug action time short, and the drug effect cannot be fully exerted; (4) The bad smell of the drug makes it difficult for patients to accept
These obviously cannot meet the needs of modern life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: This embodiment prepares 1000 pieces of 1.5×1.5cm 2 The drug film adopts the following formula:

[0025] Borneol 23mg Borax 227mg

[0026] Cinnabar 23mg Xuanming Powder 227mg

[0027] Chitosan 1550mg

[0028] First, weigh cinnabar and borax, crush them into fine powder (the cinnabar in it adopts water flying method), then mix with Xuanming powder, add appropriate amount of water and 0.1ml of glycerin, stir evenly, and set aside. Add borneol and ethanol to prepare 1% ethanol solution for later use. Take 1550mg of chitosan fine powder, add water to form a 1.5% solution, add hydrochloric acid dropwise until the solution is completely dissolved, filter, then add 1.6 times of gelatin (dissolved in water first) and stir evenly, let it stand for defoaming, then add the above-mentioned spare liquid, stirring slowly, forming a film, spraying 1% borneol ethanol solution after natural drying, and cutting into 1.5×1.5cm 2 Small pieces, 1000 pieces were made.

Embodiment 2

[0029] Embodiment 2: This embodiment prepares 1000 pieces of 1.5×1.5cm 2 The drug film adopts the following formula:

[0030] Borneol 18mg Borax 180mg

[0031] Cinnabar 26mg Xuanming Powder 220mg

[0032] Chitosan 1660mg

[0033] The preparation method is the same as in Example 1.

Embodiment 3

[0034] Embodiment 3: This embodiment prepares 1000 pieces of 1.5×1.5cm 2 The drug film adopts the following formula:

[0035] Borneol 25mg Borax 267mg

[0036] Cinnabar 20mg Xuanming Powder 200mg

[0037] Chitosan 1550mg

[0038] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention relates to a medicament for treating ulcerative stomatitis and process for preparation, wherein the medicament comprises borneol, borax, cinnabar, natrii sulfas exsiccatus and chitosan by a predetermined proportion.

Description

technical field [0001] The invention relates to a medicine for treating oral ulcer and a preparation method thereof. Background technique [0002] Recurrent oral ulceration is a localized ulcerative disease of oral mucosa that recurs. It is more common in young and middle-aged people. At present, the cause of recurrent oral ulcer is not very clear, but the related factors are complicated, such as mental stress, neurasthenia, digestive tract dysfunction, diabetes and other endocrine disorders, trace element and vitamin deficiency, abnormal immune function, genetic factors, etc. The course of disease of primary disease is longer, reaches several months, several years, even more than ten years. Seriously affect the physical and mental health of patients. [0003] Clinically, the treatment of oral ulcers is based on topical medication, and gargles, troches and medicated films are commonly used, but the effects are not ideal enough. Traditional Chines...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/28A61K9/70A61P1/02A61K31/045A61K31/722A61K33/22A61K33/04
Inventor 孔繁智陈春谢元德
Owner 浙江南洋药业有限公司
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