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Eye medicinal composition for treating acute-chronic conjunctivitis and its preparing method

A technology for chronic conjunctivitis and composition, which is applied in the field of ophthalmic pharmaceutical composition prepared from Chinese herbal medicine Chrysanthemum chrysanthemum as raw material and its preparation, which can solve the problems of not forming a product and achieve small side effects, definite curative effect and stable quality controllable effect

Inactive Publication Date: 2006-08-09
成都三明药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the wild chrysanthemum injection has also been reported to be used for ophthalmic diseases, due to the different extraction methods of raw materials, the quality requirements of injections and eye drops are different, and the selection of additives is different. Due to the particularity of the ophthalmic environment, the injection cannot be used directly. Eye drops. At present, there is no report on the preparation of ophthalmic preparations from wild chrysanthemum, and there is no report on the formation of related products.

Method used

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  • Eye medicinal composition for treating acute-chronic conjunctivitis and its preparing method

Examples

Experimental program
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Embodiment 1

[0024] The preparation of embodiment 1 drug eye drops of the present invention

[0025] 1. Raw materials: wild chrysanthemum flower 1000g, Tween 80 5ml, glycerin 8ml, boric acid 8g, 20% sodium hydroxide in proper amount to prepare 1000ml

[0026] 2. Preparation process

[0027] 1. Take 1000g of wild chrysanthemum, add 10 volumes of water to soak for 1 hour, steam distill, collect 1000ml of the first distillate, and then redistill, collect 500ml of the double distillate for later use;

[0028] 2. Collect the decoction liquid in the medicinal dregs, filter, add 8 amounts of water to the medicinal dregs, decoct twice, each time for 1 hour, filter, combine the filtrate, and concentrate to a relative density of 1.14-1.18 (40-70°C ) clear ointment, add ethanol to make the alcohol content reach 65%, refrigerate, and let stand for 12 hours;

[0029] 3. Filtrate, recover ethanol and concentrate to a clear paste with a relative density of 1.16-1.22 (40-70° C.), let it cool, add ethano...

experiment example 2

[0032] The preparation of experimental example 2 medicine eye drops of the present invention

[0033] The preparation process is the same as in Example 1, except that the dosage is changed: 1200g of wild chrysanthemum, 80 8ml of Tween, 10ml of glycerin, an appropriate amount of 20% sodium hydroxide, and 10g of boric acid;

experiment example 3

[0034] The preparation of experimental example 3 medicine eye drops of the present invention

[0035] The preparation process is the same as in Example 1, except that the dosage is changed: 800 g of wild chrysanthemum, 3 ml of Tween 80, an appropriate amount of 20% sodium hydroxide, and 6 g of boric acid;

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Abstract

The present invention relates to an eye medicine composition for curing acute and chronic conjunctivitis and its preparation method. It is an eye preparation made up by using extract of chrysanthemum indicum.L. as active component and adding auxiliary materials through a certain preparation process. Besides, said invention also provides the concrete steps of its preparation method.

Description

technical field [0001] The invention relates to an ophthalmic pharmaceutical composition for treating acute and chronic conjunctivitis and a preparation method thereof, specifically, an ophthalmic pharmaceutical composition prepared from the Chinese medicinal material Chrysanthemum chrysanthemum as a raw material and a preparation method thereof, belonging to the field of pharmaceuticals . Background technique [0002] Conjunctivitis is a frequently-occurring disease in ophthalmology, accounting for the first place in conjunctivitis. Its etiology is nothing more than microbial and non-microbial two categories. As far as microbes are concerned, bacteria, viruses, parasites, etc. can cause conjunctival inflammation, and the sources are very extensive, which can be directly from the outside world or from the self, and self-infection may be transferred to the conjunctiva through the blood stream or lymph ( Tuberculosis, etc.); or directly spread from adjacent tissues, such as ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61K9/08A61K9/00A61P27/02A61K133/00
Inventor 阳向波谢永平张媛
Owner 成都三明药物研究所
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