Valerianoil liquid hard capsule, and its preparing method

Abstract

The present invention relates to a valerian oil liquid hard capsule and its preparation method. Said capsule preparation is composed of hard capsule shell and liquid materials of valerian oil or valerian extract as main component. Said capsule preparation has the obvious effects of sedative-hypnotic, reducing bloedlipid, reducing blood pressure, improving myocardial microcirculation, resisting bacteria, resisting virus, resisting tumor and resisting fatigue, etc.

Description

technical field [0001] The invention relates to the fields of medicine and health care products, in particular to a valerian oil or valerian extract liquid, a soft material hard capsule and a preparation method thereof. Background technique [0002] The valerian root extract used in medicine and health care products is extracted from natural plants or artificially planted valerian root, which contains volatile oil or liquid soft substances, and has sedative, hypnotic, anticonvulsant, antidepressant, coronary vascular Blood pressure, regulating blood lipids, anti-arrhythmia, improving myocardial microcirculation, anti-oxidation, anti-fatigue, antibacterial, antiviral, antitumor and other effects. [0003] At present, the application of valerian root extract in the field of medicine includes the following main formations. The first is to add valerian root extract to starch, mix well, granulate, heat and dry to make granules, and then pack into hard cap...

AI Technical Summary

Problems solved by technology

[0003] At present, the application of valerian root extract in the field of medicine includes the following main formations. The first is to add valerian root extract to starch, mix well, granulate, heat and dry to make granules, and then pack into hard capsules for patients to take. As we all know, valerian oil and valerian extract are easily volatile substances, because their active ingredients are damaged or lost through heating, spray drying, crushing, granulation and other processes during processing, especially the volatile oil has been mostly Volatilization makes the bioavailability not high and affects the biological activity. Moreover, after filling the hard capsule, because there is no seal at the capsulation of the capsule, the quality and efficacy of valerian oil will decrease due to its own volatilization during storage and transportation, affecting curative effect

[0004] Its two, valerian oil is made soft capsule through liquid mode, and this soft capsule can effectively overcome the volatilization defect of valerian oil, but the soft capsule in the prior art is mainly made of gelatin and glycerin, and its The capsule wall layer is relatively thick, some reaching more than 0.5mm, and the disintegration time limit will be delayed over time, so that the disintegration after oral administration is unqualified. Volatilize valerian oil and affect the soft capsule shell, making it easier to solidify and denature, seriously affecting the curative effect

[0005] In summary, the Valeriana officinalis extract in the prior art market is made into different preparations and there is a certain image of unstable quality. For these unsatisfactory defects, the applicant has finally developed a new product after many years of research and practice. Valerian oil liquid hard capsule and preparation method thereof