Composition of Chinese traditional medicine, preparation method, and quality control method
A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as not seen, and achieve the effects of reducing the number of writhing times, prolonging the latency period of the pain threshold, and enhancing the transformation function of lymphocytes
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
experiment example 1
[0039] Experimental example 1 Research on the technical conditions of the extraction process of the pharmaceutical composition of the present invention
[0040] 1. Selection of extraction solvent and concentration:
[0041] The main active ingredients in the formula are flavonoids and saponins, which can be dissolved in water and ethanol. The solvent and its concentration are the most important factors affecting the extraction effect. In order to extract the active ingredients as completely as possible, the following experiments were designed with the total flavonoids, total saponin yield, and pharmacodynamic antipyretic effect as the investigation indicators:
[0042] According to the proportioning relationship of 5 parts by weight of Bupleurum, 4 parts by weight of Scutellaria baicalensis, 4 parts by weight of Pueraria Radix, and 3 parts by weight of Glycyrrhizae, 5 parts of medicinal materials are weighed, each part is 160g, and 4 times the amount of water and different con...
experiment example 2
[0119] Experimental Example 2 Research on the separation, purification, concentration and drying process of the composition of the present invention:
[0120] 1. Research on the concentration process of the crude extract:
[0121] Take a total of 480g of the four medicinal materials in the same proportion, add 1920ml of 70% ethanol to heat and extract for 1.5 hours, extract 4 times, filter while hot, combine the filtrate, recover the solvent under reduced pressure (0.095MPa, 65°C), concentrate to 240ml, and measure the relative density It is 1.15-1.20.
[0122] Take 10ml liquid extract and dry, add 40ml distilled water, ultrasonic treatment (power 250W, working frequency 29KHz) for 10 minutes, refrigerate in refrigerator for 48 hours, vacuum filtration (0.095MPa), complete in 3 hours, insoluble solids are dried and weighed. (method one)
[0123] Take another 10ml of liquid extract, add 30ml of distilled water directly, stir, refrigerate for 48 hours, filter under reduced pre...
experiment example 3
[0148] Experimental Example 3 Screening of the present invention's capsule preparation adjuvant and its dosage
[0149] Taking the appearance and disintegration as indicators, the experiment investigated the effects of different dosages and mixing ratios of three excipients—starch, dextrin, and β-cyclodextrin. The experiment designed 11 small sample prescriptions as shown in Table 20. .
[0150] prescription number
Medicinal extract (g)
Starch (grams)
β cyclodextrin (g)
Dextrin (g)
1
2
3
4
5
6
7
8
9
10
11
20
16
16
16
16
16
16
14
12
10
8
0
4
0
0
2
2
0
0
0
0
0
0
0
4
0
2
0
2
0
0
0
0
0
0
0
4
0
2
2
6
8
10
12
[0151] Weigh the medicine and auxiliary materials according to the prescription amount in the...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com