55results about How to "Activate phagocytosis" patented technology

A Chinese medicine for treating cold is proportionally prepared from bupleurum root, scutellaria root, pueria root and liquorice root. Its preparing process and its quality control method are also disclosed.

The invention discloses a medicine for treating post-chemotherapy leucopenia and a preparation method thereof. The medicine consists of the following raw materials in part by weight: 2 to 20 parts of ginseng, 5 to 50 parts of astragalus, 5 to 50 parts of gensing, 5 to 50 parts of largehead atractylodes rhizome, 5 to 30 parts of epimedium, 5 to 20 parts of malaytea scurfpea fruit, 5 to 30 parts ofChinese angelica, 5 to 50 parts of suberect spatholobus stem, 5 to 50 parts of medlar, 5 to 30 parts of dwarf lilyturf tuber, 3 to 25 parts of bupleurum, 3 to 35 parts of largetrifoliolious bugbane rhizome and 1 to 15 parts of pangolin scales. According to the preparation method, the Chinese medicinal composition is prepared according to a method for the conventional preparation of Chinese medicines, wherein the conventional preparation comprises a water decoction, an oral liquid, granules, capsules or powder and the like. According to the medicine, a prescription for treating post-chemotherapy leucopenia is created on the basis of clinical experiences of multiple years, and a curative effect is obvious.

The invention relates to an anti-contamination skin care composition and a cosmetic. The anti-contamination skin care composition comprises a substrate and the following components by weight percent:1.5-3% of chlorella extract, 2-6% of trehalose, and 1-3% of dimethyl methoxy chromanol. The anti-contamination skin care composition effectively forms an anti-contamination barrier for the skin, the tolerance of an irritant of the skin is improved, the PM2.5 of the skin is deeply removed, the oxidation resistance of the skin is improved, the cell and the DNA damage are repaired, and the anti-contamination skin care composition can resist the skin injury caused by ultraviolet light.

The invention discloses a pollen natto tablet, which comprises the following components in parts by weight: 4-5 parts of pollen, 3-4 parts of natto, 1-2 parts of anka and 1-2 parts of oligosaccharide. The pollen uses bee pollen as a raw material. The method for preparing the pollen comprises the following steps: firstly sprying the raw material bee pollen with 50-100PPM ClO2 aqueous solution; sterilizing for 30 minutes in a closed manner; adjusting humidity to 25%; then inoculating ferments to ferment at the temperature of 30-37 DEG C for 12 hours; and verifying acidity, cryodrying to obtain the pollen when the PH value is 4.5. The pollen natto tablet of the invention generates secondary products such as multiple enzymes, lactic acid, vitamin and the like after the raw material is fermented with beneficial bacterium, and combines the health care functions of the raw material and beneficial microorganisms, therefore the pollen natto tablet can supply human body with balanced nutrition, adjust human body endocrine metabolism, promote recovery of certain diseases, and improve human sub-health state.

The invention discloses a recombinant protein prepared based on a SIRP-alpha-D1 mutant and application. A mutant I is obtained on the basis of performing contact surface amino acid multi-point mutation on an outer end IgV area (SIRP-alpha-D1) of a SIRP alpha film, a mutant II is obtained by performing deglycosylation mutation on an amino acid asparaginate (N) at the 80th site on the basis of the mutant I, and a human IgG1-Fc area is coupled for performing fusion expression to obtain the recombinant protein CD001/CD002. Compared with a wild-type or deglycosylation single-point mutant, these mutants have higher affinity with the recombinant protein CD47 and multiple types of cancer cell lines, and have a better blocking effect on CD47 and SIRPa combination in a protein level and a cell level; the mutants have no blood clotting to a white blood cell (a red blood cell); and in the aspect of function, the mutants are capable of more effectively activating phagocytosis of macrophage to a tumor cell. The CD001/CD002 has better target spot bonding activity, better target spot blocking effect and stronger immune activation function, and has no side effect to the red blood cell.

The invention relates to a special animal biogen for shrimps and a preparation method thereof. The special animal biogen comprises raw materials of feed-grade fulvic acid, total flavones from taraxaci herba and a bitter soybean meal fermentation culture, wherein the bitter soybean meal fermentation culture comprises bitter soybean meal substrates and inoculums; the bitter soybean meal substrates comprise bitter soybean meal, maize meal and beet molasses; the inoculums comprise saccharomyces cerevisiae, lactobacillus plantarum, bacillus subtillis and live bacillus licheniformis which have total sum of the number of 1*10<8> to 10*10<8>cfu/g; the total sum of the number of bacillus subtillis and live bacillus licheniformis is 3*10<8> to 8*10<8>; the number of the saccharomyces cerevisiae is 0.5*10<8> to 3*10<8>; and the number of the lactobacillus plantarum is 0.5*10<8> to 2*10<8>. With the adoption of the special animal biogen for the shrimps, the technical defects of serious drug resistance, reduction of immunity, endogenous infection, double infection, harm for human health and the like caused by unreasonable use of large amount of antibiotics in the prior art are effectively overcome, and the effects of promoting growth, improving immunity, preventing and resisting diseases and improving animal product quality are achieved by repairing, regulating and exciting a digestive system and an immune system of an animal. The special animal biogen for the shrimps is a natural green product free of hormone.

The invention relates to the field of pharmaceutical technology, particularly to a spray for treating diseases caused by human papilloma viruses and a preparation method. The spray comprises, by volume ratio, 1 ml of rabies purified vaccine for human use and 9 ml of chitosan-acetic acid solution with a prepared mass volume concentration being 0.01 g/ml to 0.03 g/ml, wherein the chitosan-acetic acid solution is prepared by fully dissolving 10g to 30g chitosan and the acetic acid solution until the volume reaches 1000 ml. The preparation method comprises the steps of first preparing 0.3% to 1.0% of the acetic acid solution and then preparing the chitosan-acetic acid solution; adding 1 part of the rabies purified vaccine for human use with an active content being 5 IU to 20 IU by volume to a measuring flask with a volume of 10 parts, adding the chitosan-acetic acid solution, and diluting for preparing the vaccine solution. The spray and the preparation method thereof in the invention is focused on follow-up treatments (Tc subgroup detection, HPV detection and improvement of clinical symptoms) of cervical carcinoma patients infected by HPV, HPV-infected people, and venereal diseases, cervical erosion and chronic cervicitis caused by HPV infection, and achieves good clinical results.

The invention discloses animal biogen special for pigs and a preparation method thereof. The animal biogen comprises the following raw materials: feed-grade fulvic acid, total dandelion flavonoids and bitter bean pulp fermentation culture; the bitter bean pulp fermentation culture comprises bitter bean pulp substrate and inoculation liquid, wherein the bitter bean pulp substrate comprises bitter bean pulp, corn meal and beet molasses; and the inoculation liquid comprises saccharomyces cerevisiae, lactobacillus plantarum, bacillus subtillis and living bacillus licheniformis. The animal biogen is prepared from probiotics such as lactobacillus plantarum and fulvic acid serving as raw materials, multiple Chinese medicinal herbs capable of improving the functions of intestines and stomach and improving the immune functions of animals and other nutritional substances by scientific compatibility and compounding. The animal biogen is a natural green product with the effects of promoting growth, improving the immunity, preventing and resisting diseases and improving the quality of an animal product by repairing, regulating and exciting the digestive systems and the immune system of an animal.

The invention relates to a special animal biogen for laying hens and a preparation method of the special animal biogen. The special animal biogen comprises the following ingredients: feed grade fulvic acid, dandelion general flavone and bitter soybean meal fermentation culture, wherein the bitter soybean meal fermentation culture comprises bitter soybean meal substrates and inoculation liquid, the bitter soybean meal substrates comprise bitter soybean meal, corn flour and beet molasses, the inoculation liquid comprises saccharomyces cerevisiae, lactobacillus plantarum, bacillus subtillis and bacillus licheniformis, wherein the total sum of the viable bacterium number of the saccharomyces cerevisiae, the lactobacillus plantarum, the bacillus subtillis and the bacillus licheniformis is 1*10<8>-10*10<8> cfu/g, the total sum of the viable bacterium number of the bacillus subtillis and the bacillus licheniformis is 2*10<8>-6*10<8> cfu/g, the viable bacterium number of the saccharomyces cerevisiae is 3*10<8>-7*10<8> cfu/g, and the viable bacterium number of the lactobacillus plantarum is 0.5*10<8>-2*10<8> cfu/g. The effects of promoting the growth, improving the immunity, preventing and resisting diseases and improving animal product quality are reached through restoring, regulating and exciting the digestive system and the immune system of animal bodies per se. The special animal biogen belongs to a natural green product without any hormone.

The invention discloses a fish feed prepared from biogas residue prepared from pig manure, straw, and melon and fruit peel, and a preparation method thereof. According to the preparation method, pig manure is subjected to harmlessness processing; the fish feed is prepared from biogas residue obtained via biogas fermentation, and is used for fish farming; so that environmental pollution caused by pig manure is avoided, and novel feed resources and processing methods are provided for breeding industry. The fish feed is used for fish farming, and is capable of promoting absorption and utilization rate of fish on nutrients, increasing feed conversion rate, improving fish health, promoting fish growth, reducing culturing investment, and saving fund.

A Chinese herbal medicine-containing feed for promoting growth of goslings comprises, by weight, corn stalks, fish meal, soybean meal, rapeseed cakes, zeolite powder, edible salt and calcium hydrogen phosphate, and 1-2% of above materials are added to a Chinese herbal medicine formula. The purpose of the invention is to provide the Chinese herbal medicine-containing feed for promoting growth of goslings. A Chinese herbal medicine feed additive contains various bioactive substances or growth promoting factors, and promotes the growth of geese by increasing the utilization rate of nutrient substances; and a part of the additive also contains a seasoning, so the appetite of the geese is promoted, and the quality of goose meat is improved. Polysaccharides, glycosides and organic acids are main effective active ingredients in the Chinese herbal medicine feed additive, so the immune system of the gees is regulated. The Chinese herbal medicine-containing feed containing various bioactive ingredients can effectively increase the nutrition of the geese, improve the body metabolism, promote the growth of the geese and improve the muscle quality.

The invention aims to provide a traditional Chinese medicine preparation for treating livestock psoriasis remarkable in treatment effect, free from toxic and side effects, free from tolerance and economic, effective and convenient. The preparation comprises the following raw materials in parts by weight: 1-10 parts of eriocarpous glochidion leaf, 1-10 parts of field bindweed, 1-10 parts of ice grass, 1-10 parts of cortex dictamni, 1-10 parts of radix angelicae, 1-10 parts of Lonicera confusa DC, 1-20 parts of cocklebur fruit, 10-20 parts of bark of himalayan coralbean, 10-20 parts of common andrographis Herb, 10-20 parts of wartwort, 10-20 parts of centella asiatica, 10-20 parts of Polygonum aviculare, 20-30 parts of lotus root starch, 20-30 parts of mulberry, 20-30 parts of Polygonum multiflorum, 20-30 parts of Semen sesami nigrum, 20-30 parts of bee pollen, 20-30 parts of cactus, 30-40 parts of tribulusterrestris, 30-40 parts of golden-rod, 30-40 parts of Ferula asafetida, 30-40 parts of calomel, 30-40 parts of lithargite and 30-40 parts of Mosla dianthera.

The invention relates to nutrition food of a menstruation regulating tea granule beneficial for menstruation regulation and belongs to the field of nutrition food. The menstruation regulating tea granule aims at realizing the goals of good effect and fast effect taking and is prepared from ingredients including purslane, rehmannia, cortex moutan radicis, madder, tremella, black tea and the like. The menstruation regulating tea granule has the effects of supporting body resistance, nourishing yin and blood, removing heat from the liver, cooling the blood to promote the blood circulation and stopping the bleeding to regulate the menstruation, and has the advantages of good effect and high effect taking speed.

The present invention relates to an antiviral bacteria-killing cleaning detergent with several health-care functions. Said cleaning detergent is made up by using the raw materials of water, edible acetin, edible vinegar, garlic, onion, clove, cinnamon bark, nutmeg, origanum, hot pepper, grape, thymus mongolicus, gleditsia fruit and sorbate through a traditional preparation process. Said invention also provides its application range.

The invention provides a preparation method of a cordyceps sinensis multi-vitamin beverage containing nano-selenium. The cordyceps sinensis multi-vitamin beverage is mainly characterized by comprising8-12 parts of a nano-selenium cordyceps sinensis extracting solution, 2-3 parts of small molecule peptide, 2-3 parts of honey, 2-5 parts of brown sugar, 1-2 parts of apple vinegar, 10-15 parts of lactic acid bacteria, 0.5-1 part of vitamin E and 3 parts of glucose. The nano-selenium edible fungus nutrient solution is used for culturing nano-selenium-rich cordyceps sinensis, the preparing cordyceps sinensis micro-powder is prepared, and the preparing cordyceps sinensis micro-powder has the advantages of being rich in small molecule peptides, trace elements such as selenium, zinc, iron, copper,manganese, chromium, vanadium and the like necessary for human bodies, and nutritional ingredients such as various enzymes and amino acids synthesized by the trace elements. Cholesterol and triglyceride can be obviously reduced, metabolic decomposition of cholesterol and triglyceride is promoted, low-density lipoprotein is removed, and cardiovascular and cerebrovascular health is protected. Selenium can eliminate peroxides generated in metabolic activities of organisms and protect cell membranes from being damaged by oxides, so that cells of the organisms are intact, organ functions are normal, and various important organs such as heart, liver, spleen, lung and kidney of the human body are protected.

The invention aims at providing a traditional Chinese medicine formula for curing pediatric chronic urticaria, which has a good treatment effect and no side effect. The traditional Chinese medicine formula for curing pediatric chronic urticaria is characterized by being prepared from the following raw materials by weight portion: 10-20 portions of Coptis chinensis, 10-20 portions of fructus forsythiae, 10-20 portions of water chestnut, 10-20 portions of eriocarpous glochidion leaf, 10-20 portions of herb of longfruit speedwell, 10-20 portions of nettle, 10-20 portions of cimicifugae foetidae, 10-20 portions of herba portulacae, 1-10 portions of herb of Chinese goldsaxifrage, 1-10 portions of soapstone, 1-10 portions of radix sileris, 1-10 portions of cassia twig, 1-10 portions of lithospermum, 1-10 portions of great burdock achene, 20-30 portions of saffron crocus, 20-30 portions of lalang grass rhizome, 20-30 portions of periostracum cicada, 20-30 portions of fructus kochiae, 20-30 portions of gypsum powder, 20-30 portions of bee pollen and 20-30 portions of peppermint oil.

The invention relates to a non-erythrocyte agglutination anti-PD-L1/CD47 bispecific antibody and application thereof in anti-tumour treatment. Specifically, the invention provides an anti-PD-L1/CD47 bispecific antibody or an antigen binding fragment thereof; the anti-PD-L1/CD47 bispecific antibody can be specifically bound with PD-L1 and CD47 molecules; binding of PD-L1 and PD-1 and binding of CD47 and SIRP alpha can be blocked at the same time after binding; T cells and macrophages are further activated to achieve the biological effects of resisting tumours and the like; and meanwhile, the antibody does not cause erythrocyte agglutination.

The invention discloses a fish feed prepared from biogas residue prepared from animal and human manure, and a preparation method thereof. According to the preparation method, animal and human manure is subjected to biogas anaerobic fermentation; the fish feed is prepared from biogas residue obtained via biogas anaerobic fermentation, and is used for fish farming; so that environmental pollution caused by animal and human manure is avoided, and novel feed resources and processing methods are provided for breeding industry. The fish feed is used for fish farming, and is capable of promoting absorption and utilization rate of fish on nutrients, increasing feed conversion rate, improving fish health, promoting fish growth, reducing culturing investment, and saving fund.