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152results about How to "Accurate target" patented technology
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Apparatus and method for calculating aiming point information
InactiveUS20050021282A1Precise positioningEasy to adjustSighting devicesDigital computer detailsComputer architectureTarget acquisition
The present invention relates to target acquisition and related devices, and more particularly to telescopic gunsights and associated equipment used to achieve shooting accuracy at, for example, close ranges, medium ranges and extreme ranges
Owner:HVRT CORP
Apparatus and method for calculating aiming point information
InactiveUS7937878B2Precise positioningEasy to adjustSighting devicesComputer architectureMedium range
Owner:HVRT CORP
Apparatus and method for calculating aiming point information
InactiveUS20090235570A1Precise positioningAccurate targetOptical rangefindersSighting devicesComputer architectureTarget acquisition
The present invention relates to target acquisition and related devices, and more particularly to telescopic gunsights and associated equipment used to achieve shooting accuracy at, for example, close ranges, medium ranges and extreme ranges at stationary and moving targets.
Owner:HVRT CORP
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9 system capable of simultaneously knocking out KRAS genes and EGFR (Epidermal Growth Factor Receptor) genes and application thereof
ActiveCN107130000AHigh knockout efficiencyEasy to operateOrganic active ingredientsHydrolasesAbnormal expressionKRAS
The invention discloses a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9 system capable of simultaneously knocking out KRAS genes and EGFR genes. The system comprises sgRNA for specifically targeting KRAS genes and sgRNA for specifically targeting EGFR genes, wherein a corresponding DNA sequence of the sgRNA for specifically targeting KRAS genes is shown as SEQ ID NO.1 or / and SEQ ID NO.2; and a corresponding DNA sequence of the sgRNA for specifically targeting EGFR genes is shown as SEQ ID NO.11 or / and SEQ ID NO.12. The invention further discloses application of the system in preparation of medicines for treating cancers. The CRISPR-Cas9 system disclosed by the invention is capable of simultaneously and efficiently knocking out two cancer driving factors KRAS and EGFR which are highly-expressed in lung cancer. The system is simple in operation and high in knockout efficiency and is expected to be applied to treatment of the lung cancer. The system disclosed by the invention is applicable to multiple cancers with abnormal expressions of the EGFR and KRAS.
Owner:浙江卫未生物医药科技有限公司
Light curtain array automatic scoring round target device and method
InactiveCN101149245AAchieving Stereoscopic Data AcquisitionRealize multivariate data collectionTarget detectorsSensor arrayExact location
This invention discloses an automatic target-reporting method and system for indoor and outdoor bullet shooting. It includes veiling sensor array, signal collection, coordinates computation and display parts. The basic cell array of the veiling sensor is composed of a linear light source L and corresponding receiving device. The linear light source L is composed of light-emitting diodes that are arranged in line. The receiving device S is formed by the end face of optical fiber. The veiling sensor is three-dimensional frame structure. Two parallel veiling are used together in the X and Y computed coordinate directions. Each of them has two V shaped veiling which form alpha angle with the two parallel veiling. Thus, they form the special veiling sensor array. Only four sets of veiling basic cell arrays can fulfill the three-dimensional no touch measurement of the bullet. It can give the exact location and speed of the bullet on the target. The rate of false reporting rate is low. It will not be interfered by adjacent target.
Owner:XIAN TECHNOLOGICAL UNIV
Systems and methods for contaminant detection within a fluid, ultraviolet treatment and status notification
InactiveUS7160370B2Reduce infectivityHarmful effectCombination devicesAuxillary pretreatmentUltravioletDistribution system
A fluid-borne (e.g., water, air) biological and chemical hazard detection and treatment system can include sensors (e.g., flow rate, contaminant detectors), treatment using ultraviolet laser-emitted light, can be microprocessor controlled and can communicate and be controlled over data networks. Treatment and detection systems can be deployed at various stages along a fluid distribution system, allowing for protection coverage and redundancy. During treatment, fluid enters into and / or passes through a “treatment area” wherein the fluid is subjected to light emanating from a laser at wavelengths within the ultraviolet range. DNA for microorganisms contained within fluid (including blood) are reactive to laser light as they pass through treatment areas and are rendered un-infective. Treatment systems can be staged in close proximity, providing more than one treatment area and associated light sources to a fluid stream. Such staging can provide for concentrated redundancy prior to its delivery to the intended point of use.
Owner:SALTECH CORP
Horizontal branch multi-well-group butted well and construction method thereof
ActiveCN103216234AGuarantee normal implementationAvoid cloggingUnderground miningFluid removalWell drillingHorizontal branch
The invention discloses a horizontal branch multi-well-group butted well and a construction method thereof. The butted well adopts a distribution structure that a horizontal well corresponds to at least two vertical well groups; each vertical well group comprises at least two vertical wells; the vertical wells of each vertical well group are respectively communicated with the horizontal well at the target points respectively arranged at the bottoms of the vertical wells, so that horizontal mining channels which correspond to the vertical well groups one to one can be formed; and the target points arranged at the bottoms of the vertical wells are arranged in a target ore bed. By adopting a novel well drilling distribution form, the horizontal branch multi-well-group butted well enlarges the bare area of the ore bed, improves the mining efficiency, lowers the well drilling cost, reduces the construction period and reduces the mining risk.
Owner:EXPLORATION TECH RES INST OF CHINESE ACADEMY OF GEOLOGICAL SCI +1
Image denoising method based on non-local means and multi-level directional images
ActiveCN101847257AQuality improvementAccurate targetImage enhancementCharacter and pattern recognitionPrincipal component analysisDecomposition
The invention relates to an image denoising method based on non-local means and multi-level directional images, comprising the steps of: firstly, carrying out preprocessing on an image with noise in an empty space by utilizing a non-local mean arithmetic of a small window and the similarity of the local structure of the image, and mapping the local window to a low-dimensional space to improve the speed of the arithmetic by utilizing principal component analysis (PCA); then carrying out multi-scale multi-direction sparse decomposition on the preprocessed image through NSCT (Non-subsampled Contourlet); eliminating low-frequency noise by adopting Wiener filtering in an NSCT transform domain by utilizing the neighborhood statistical property of the coefficient; and obtaining the denoised image through NSCT inverse transformation. The method improves the quality of the denoised image, provides more comprehensive and accurate targets and background information, and achieves relatively ideal denoising effect. The invention has wide application prospect in systems in the military field and the non-military field such as optical imaging, target detection, safety monitoring, and the like.
Owner:SHANGHAI UNIVERSITY OF ELECTRIC POWER +1
Multimodally altered cells as a form for administering active substances and as diagnostic particles
InactiveUS20060270030A1Accurate targetPrecise positioningDead animal preservationTissue cultureCompound (substance)In vitro
The present application demonstrates that both active substances and diagnostically effective substances can be introduced into biological cells, in particular blood cells, simultaneously. These multimodally altered cells can be found once again, in vivo and in vitro, using modern imaging methods. In addition to the diagnostic and active compound-carrier principles, they can serve as a form for administering the active substances in an accurately targeted manner.
Owner:CHARITE UNIVS MEDIZIN BERLIN +1
Diagnosing and treating movement disorders
ActiveUS20160198998A1Precise positioningImprove accuracyNervous disorderElectrotherapyMuscle groupSacroiliac joint
A system for obtaining and analyzing data for overall joint motion from a plurality of joints of a subject experiencing a movement disorder involves a plurality of kinematic sensors configured to be placed on a body of a subject experiencing a movement disorder proximal a plurality of joints of the subject. The kinematic sensors are selected to measure overall joint motion with sufficient degrees of freedom for individual joints so that data collected by the sensors can be deconstructed into multiple degrees of freedom for individual joints and analyzed to provide amplitude of the movements caused by the movement disorder and / or relative contributions from and / or directional bias for each muscle group that may be implicated in the movement of each joint. Such a system permits methods for determining a treatment regimen for treating the movement disorder, whereby the treatment regimen is based on the amplitude of the movements and / or the relative contribution and / or directional bias of each muscle group to the movements caused by the movement disorder.
Owner:MDDT
Visible-light and infrared imaging merging method based on Contourlet conversion
A method for fusing visible light with infrared-ray image based on contourlet transform generates fusion coefficient of contourlet domain by utilizing different characteristic of visible light and infrared-ray image and by utilizing different fusion policy of high frequency detailed portion and low frequency background portion based on contourlet decomposition of inputted visible light and infrared-ray image then obtains fused image through contourlet counter transform.
Owner:SHANGHAI UNIV
Automatic millimeter wave image target identification method and device
ActiveCN106529602ASolve the problem that it is difficult to obtain good detection resultsImprove target recognition abilityCharacter and pattern recognitionGoal recognitionIdentification device
The invention discloses an automatic millimeter wave image target identification method and a device. The method comprises steps that (1), sub image blocks of a to-be-identified target millimeter wave image are acquired; (2), based on a trained convolutional neural network, target containing probability values of the sub image blocks are acquired; (3), based on the probability values, a probability cumulative graph of the to-be-identified target millimeter wave image is acquired; and (4), based on the probability cumulative graph, target marking is carried out so as to accomplish target identification of the to-be-identified target millimeter wave image. The invention further discloses an automatic millimeter wave image target identification device. The device and the method are advantaged in that the device and the method are suitable for automatic millimeter wave image target identification, the excellent target identification effect is realized, a problem that employing traditional manual design characteristics for the millimeter wave image can not realize the excellent detection effect in the prior art is solved, precise target positioning is realized, false alarms are reduced, safety check efficiency is improved, and manpower cost is reduced.
Owner:SHANGHAI INST OF MICROSYSTEM & INFORMATION TECH CHINESE ACAD OF SCI
Ice dispensing chute
ActiveUS6964351B2Easy to separateLess wetLighting and heating apparatusLiquid flow controllersLinear motionMarine engineering
An ice dispensing chute mechanism is characterized by an ice chute adapted for attachment at an upper ice inlet end to an ice retaining bin at an ice outlet from the bin. An actuating arm is pivotally mounted on the ice chute and has a lower end for being contacted and moved by a receptacle into which ice is to be dispensed from a lower ice discharge end of the chute and an upper end for contacting and moving a linkage mechanism upon rotation of the actuating arm by the receptacle. The linkage mechanism is pivotally mounted on the ice chute and is coupled to an ice gate that is linearly moved by the linkage mechanism between open and closed positions that establish and interrupt communication between the upper inlet to the chute and the ice outlet opening from the bin. Movement of the linkage mechanism by the actuating arm operates the linkage mechanism to translate the rotational movement of the actuating arm into linear movement of the ice gate between its open and closed positions to dispense ice and to cease dispensing ice into the receptacle. The ice chute consists of two halves that snap together in a releasable manner to permit easy disassembly of the ice chute for cleaning, repair or replacement of parts. The upper inlet to the ice chute is configured to impart to ice particles a trajectory through the chute that guides the ice particles into the receptacle while preventing the vast majority of the ice particles from contacting interior surfaces of the chute.
Owner:MARMON FOODSERVICE TECH INC
Macrophages capable of targeting tumor cells and preparation method thereof
ActiveCN109266618AActivate phagocytosisEasy accessPolypeptide with localisation/targeting motifImmunoglobulin superfamilyCAR T-cell therapyAntigen receptors
Owner:赛元生物科技(杭州)有限公司
Method based on Contourlet transformation, modified type pulse coupling neural network, and mage amalgamation
InactiveCN1873693AQuality improvementRich background informationImage enhancementGeometric image transformationNerve networkImaging quality
The invention relates to an image fusion method based on Contourlet transform and modified pulse coupling neural network (PCNN), on the basis of multidimensional and multidirectional Contourlet resolution of input visible and infrared images, modifying the PCNN with neural physiological background, using the modified PCNN to make fusion policy design, fusing high frequency detail part and low frequency background part according to different characteristics of the visible and infrared images, and generating Contourlet-domain fusion coefficients, and finally obtaining the fused image by inverse Contourlet transform. And the method can improve fused image quality, achieving more ideal fusion effect and has a wide application prospect in optical imaging system, target detecting system, security monitoring system, and other systems.
Owner:SHANGHAI UNIV
Vehicle front target detection method based on characteristic-point mutual information content and optical flow method
ActiveCN104881645AShorten the timeAccurate targetCharacter and pattern recognitionColor imageGray level
The invention discloses a vehicle front target detection method based on a characteristic-point mutual information content and an optical flow method. The method comprises the following steps: firstly, reading color images of two adjacent frames in a video and converting the color images into gray level images; secondly, carrying out pretreatment on the gray level images, using a histogram equalization method to carry out enhancement so as to increase a resolution ratio of a target lane line; thirdly, using a method based on a median filtering to carry out smoothing process; finally, after the pretreatment is performed, using the method based on the characteristic-point mutual information content and the optical flow field to detect vehicle front motion barrier. The last step comprises: 1) extracting a characteristic point; 2) marking; 3) determining the number of angle points; 4) selecting an area; 5) calculating the mutual information content; 6) determining a angle point chain; 7) calculating an angle point optical flow; 8) determining a distance and an angle criterion and deleting the angle points possessing a same vector; 9) carrying out thresholding and acquiring a final motion barrier detection result.
Owner:NANJING GENERAL ELECTRONICS
Automatic matting method based on semantic segmentation and significance analysis
ActiveCN110751655ASave human effortVersatilityImage enhancementImage analysisPattern recognitionImaging processing
Owner:NANJING INST OF TECH
Pessary with slow-release support
The invention relates to a pessary with a slow-release support. The slow-release support is installed inside the pessary, medicines are arranged on the support, medicines are separated from the outside through micro-hole films, and diameters of micro holes of micro-hole films are in a range from 0.1 nm to 10 mm in accordance with diameters of passing medicine. Due to own movement, organ oppression and micro hole diameter limitation, medicines slowly act on a vagina and a cervix and directly act on target organs in accordance with preset speed and the clinical effect is achieved. By the aid of the pessary, a physical mode and a chemical mode can be used for curing prolapsus and supplementing hormone.
Owner:江苏奥博金医药科技有限公司
An advertisement putting system based on block chain
InactiveCN109242575AAccurate character portraitNot easily disgustedDiscounts/incentivesAdvertisementsComplete dataComputer terminal
The invention provides an advertisement putting system based on a block chain, comprising an advertisement release incentive module, an advertisement putting platform module, an advertisement medium module, a user management module and an information verification module. By adopting the block chain technology, the invention can realize the accurate portrait for the user, the data of the block chain is compared by the multi-dimensional difference, the data quality is high, the portrait of the user character is more accurate, the put advertisement contains the content that the user is interestedin, and the advertisement is not prone to make the user feel disgusted. According to the portrait of the user, only the advertisement interested by each user is reserved in the block chain, and the probability of advertisement error is reduced; Data is stored in the network, Only users can access their own complete data, the data is not accessed unauthorizedly, data security is high, advertisingmedia owners disseminate advertising through advertising media, and when clicking and watching advertising through the terminal, the users receive different levels of virtual currency rewards, this way may encourage advertising media owners and users to take the initiative to promote.
Owner:武汉聚鸿传媒文化有限公司
Method and device for manufacturing single-side nickel-plated sheet
InactiveCN101640978ASolve technical problemsSolve the technical problems of aesthetic appearanceConductive material chemical/electrolytical removalElectric resistance weldingElectroplating
The invention discloses a method and a device for manufacturing a single-side nickel-plated sheet. The method comprises the following steps: manufacturing a circuit, punching target position holes; knocking out target position holes and drilling holes; manufacturing electric resistance welding (characters); and shaping. In the invention, a drilling hole step is adjusted to be behind a copper-nickel alloy plating step so as to solve the technical problem of metal rings generated in plating. In the invention, the target position holes are arranged on a circuit pholin technological edge, and thetarget position holes are knocked out before the holes are drilled for not influencing the accuracy of the drilling holes; the punched target position holes are used for positioning the drilling holesso as to enable the holes to be more accurate and solve the technical problem of blind holes and the technical problem that the attractive appearance of the alloy surface is influenced by liquid medicine cross easily occurring in the plating. Compared with a dry film and a pholin, the invention has lower manufacture cost except for using a little more drilling tip.
Owner:SHENZHEN SUN & LYNN CIRCUITS
Obstacle avoiding method for seat returning by robot, chip, and autonomous mobile robot
ActiveCN109407675AImprove return efficiencyAccurate targetPosition/course control in two dimensionsWalking around obstaclesEngineering
The invention relates to an obstacle avoiding method for seat returning by a robot, a chip, and an autonomous mobile robot, thereby improving the seat returning efficiency of the robot. The obstacle avoiding method comprises: when a robot returns to a seat along an intermediate guidance signal and detects an obstacle, previous travel record information is analyzed; after the obstacle information is acquired, the robot goes around the obstacle by means of navigation walking and arrives at a target point quickly, thereby improving the seat returning efficiency of the robot. Under the circumstance of lack of obstacle information, the robot walks along edge with the accurate target orientation by setting a target point, so that the pertinence of the seat returning of the robot is improved; anda phenomenon that the robot walks on a wrong path when the seat returning signal intensity is poor is avoided.
Owner:AMICRO SEMICON CORP
Optical three-dimensional imaging method based on voxel and adaptive optical transmission model
The invention discloses an optical three-dimensional imaging method based on a voxel and an adaptive optical transmission model. With the method, a problem that an optical three-dimensional imaging reconstruction result can not be obtained until tedious organ segmentation and grid discretization are carried out in the prior art can be solved. According to the invention, a voxel physical model and an adaptive optical transmission mathematic model are combined organically; and a complete sparse regularization objective function is constructed and solved to realize optical three-dimensional imaging of a targeting object in vivo. The method comprises steps of data acquisition and pretreatment, voxel-based physical model construction, adaptive optical transmission mathematic model construction, system equation establishment based on enriched function fusion, objective function establishment based on a sparse regularization strategy and a prior feasible region, and objective function and display result solution. Therefore, the provided method has characteristics of high efficiency and easy usage; and an inaccurate three-dimensional imaging result due to an error caused by uncontrollable factors in organ segmentation and grid discretization can be avoided. The method can be applied to the in-vivo optical three-dimensional imaging field.
Owner:GUANGZHOU BLT INSTR & METER
Method for image noise reduction based on transforming domain mathematics morphology
InactiveCN1921562ATo achieve the purpose of image noise reductionSparse image description coefficientTelevision system detailsColor television detailsPattern recognitionImage denoising
The invention relates to an image noise-reduction method based on transformation domain mathematical morphology. Wherein, it comprises that processing Contourlet rare transformation on the input noise image with multi sizes and multi directions; then using mathematical morphology algorism to process the high-frequency factor at Contourlet domain, to remove the noise with less support domain, and effectively keep the image edge information with continuous support domain; at last, using Contourlet inverse transformation to obtain noise-reduction image, to reduce the noise of image. The invention has wide application.
Owner:SHANGHAI UNIV
Technology for rapidly constructing air shaft under chill condition and process for sinking vertical shaft pit shaft
InactiveCN101694159ARapid excavation processImprove measurement repeatabilitySurveyDirectional drillingEngineeringDrill hole
The invention discloses a process for rapidly constructing an air shaft under a chill condition, mainly comprising the following steps: creating a pore, freezing the pore, constructing a temperature-measuring pore and a hydrologic observation pore and creating a drill hole together. The process is used for sinking all vertical shaft pit shafts by sealing water through three-synchronization of freezing, slip-casting and shaft sinking in the construction process, wherein the three-synchronization refers to the synchronous construction of the preparation and the installation of a permanent shaft frame, the freezing of a surface soil section and the digging and the building of the pit shaft while the ground preliminarily slip-casting construction is carried out, a freezing method is adopted in the surface soil section, and a group preliminarily slip-casting method is adopted in a bed rock section.
Owner:中煤第一建设有限公司第四十九工程处
Intradermal delivery of vaccines and gene therapeutic agents via microcannula
InactiveUS20040131641A1Precise positioningImprove responseSsRNA viruses negative-senseAntibacterial agentsGene Therapy AgentGene
Owner:BECTON DICKINSON & CO
Green synthetic method of fluorescence copper nano-cluster, and application of fluorescence copper nano-cluster
InactiveCN103820106AAvoid harmAvoid biotoxicityMaterial nanotechnologyFluorescence/phosphorescenceTumor targetTumor targeting
The invention discloses a green synthetic method of a fluorescence copper nano-cluster, and an application of the fluorescence copper nano-cluster. The synthetic method concretely comprises the following steps: incubating a certain concentration of a copper salt solution and different kinds of tumor cells, and carrying out in-situ synthesis to obtain a copper nano-cluster having an excellent fluorescence performance in order to realize the real time and high resolution fluorescence imaging of the tumor cells. The copper nano-cluster can realize the rapid real-time in-situ in-vivo tumor targeting fluorescence imaging on a tumor-hearing nude mouse model. The copper nano-cluster is prepared through direct biosynthesis of tumor cells and has a very good biocompatibility; and the method has the characteristics of environmental protection, no pollution to the environment, realization of rapid and accurate positioning and tumor targeting imaging analysis by the in-situ synthesis reaction, simplicity, easy implementation, accuracy and high efficiency.
Owner:SOUTHEAST UNIV
Low-intensity focused ultrasound response type phase-change thrombolysis nano particles as well as application and preparation method thereof
ActiveCN109316608AGood biocompatibilityHigh biosecurityEchographic/ultrasound-imaging preparationsPharmaceutical non-active ingredientsResponse typePerfluorohexane
The invention relates to the technical field of biomedicine and discloses low-intensity focused ultrasound response type phase-change thrombolysis nano particles which comprise shell polylactic acid-glycolic acid copolymer PLGA, wherein ferrosoferric oxide Fe3O4 is embedded into the shell; perfluorohexane PFH is coated in the shell; the shell is connected with CREKA polypeptide targeting fibrin. The low-intensity focused ultrasound response type phase-change thrombolysis nano particles can solve the problem of an unsatisfactory thrombolysis effect caused by limited drug loading capacity or drug inactivity of drug-loading nano particles in the prior art.
Owner:THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIV
Pessary with slow-release support
The invention relates to a pessary with a slow-release support. The slow-release support is installed inside the pessary, medicines are arranged on the support, medicines are separated from the outside through micro-hole films, and diameters of micro holes of micro-hole films are in a range from 0.1 nm to 10 mm in accordance with diameters of passing medicine. Due to own movement, organ oppression and micro hole diameter limitation, medicines slowly act on a vagina and a cervix and directly act on target organs in accordance with preset speed and the clinical effect is achieved. By the aid of the pessary, a physical mode and a chemical mode can be used for curing prolapsus and supplementing hormone.
Owner:江苏奥博金医药科技有限公司
Traditional Chinese medicine-magnetic nanocluster chemical immunity drug delivery system and preparation method thereof
ActiveCN109045303ACirculatory stabilityAccurate targetPowder deliveryOrganic active ingredientsTumor-associated macrophageNanoparticle
The invention relates to a traditional Chinese medicine-magnetic nanocluster chemical immunity drug delivery system and a preparation method thereof. The traditional Chinese medicine-magnetic nanocluster chemical immunity drug delivery system comprises superparamagnetic oxide nanoparticles, wherein the surface of each superparamagnetic oxide nanoparticle is anchored with a drug and a TAMs (tumor-associated macrophage) targeting ligand; the superparamagnetic oxide nanoparticles form a nanocluster structure through disulfide bonds; the nanocluster structure is externally packaged with protein. The traditional Chinese medicine-magnetic nanocluster chemical immunity drug delivery system has the advantages that the target finding advantages of magnetic trend, ligand modifying and reductive sensitization are integrated; the in-vivo circulation is stable, the tumor aggregation efficiency is high, and the TAMs targeting is precise.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
Dictionary learning algorithm based on sparse model analysis
The invention relates to a dictionary learning algorithm based on sparse model analysis. According to the algorithm, a cost function is established directly through noise signals, the cost function is solved through a gradient descent method, and it is guaranteed that the value obtained through iteration conducted each time is optimal within the local range. A dictionary is adaptively updated through the algorithm, so that a super-complete dictionary capable of better expressing the image structure is formed. The dictionary learning algorithm can be used for image noise removal, image quality can be improved, more accurate target and background information can be provided, and the ideal noise removal effect can be achieved. The algorithm is widely applied to the military field and non-military field of target detection, optical imaging, safety monitoring systems and the like.
Owner:NANCHANG UNIV
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