Endovascular device with membrane

Abstract

Embodiments of a uniformly porous membrane covering an endoprosthetic device, for example, a stent used to treat an aneurysm, are described. Some embodiments have a pore size and spacing that provides a material ratio of between 70-80% in the deployed state. Material ratio is the proportion of the total porous segment of the membrane that corresponds to membrane material, the remainder being pores. In some embodiments, pore size ranges from about 10-100 μm. In some embodiments, pores are equidistantly spaced with pore spacing in a range of about 40-100 μm. The combination of pore size and spacing are effective to provide a membrane that substantially prevents flow to the aneurysm, while maintaining flow to perforator vessels. In some embodiments the membrane includes permanently attached agents that promote attachment of endothelial cells or progenitors and healing of the aneurysm, or reduce immune responses detrimental to the healing process.

Description

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AI Technical Summary

Benefits of technology

The present invention relates to methods for treatment of bodily vessels containing an aneurysm. An endovascular device is used which includes an expandable member that can be expanded inside the patient's body vessel to create a new channel for blood flow. A membrane covers this expanable member and has multiple small holes called pores. These pores are evenly spaced and have a specific size. When the expandable member is placed in the body vessel, these tiny openings allow blood cells to pass through and enter other nearby vessels without causing excessive bleeding. This technique also helps promote growth of healthy vascular tissues around the treated areas. Overall, this approach provides improved results compared to traditional surgery techniques while minimizing risks associated with brain damage during rupture of the aneurysm.

Problems solved by technology

The technical problem addressed in this patent text relates to developing a stent for repairing blockages in blood vessels without causing allergic reactions or injury to the patient. The ideal stent needs to be easy to insert into the affected area, flexible enough to adapt to changes in the size of the lesion, able to promote tissue healing instead of clump formation, resistant to bacterial responses, and capable of being made in a cost-effective manner. Current techniques involve placing the stent in a host vein or introducing a preformed stent designed to avoid excessive removal of the protective sleeight. This requires manipulation of multiple factors including selecting the type of material, age, and thickness of the covering, and whether to maintain bioactivity or remove the risk of forming new ones.

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