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Low alcohol content disinfection foams

Inactive Publication Date: 2016-04-21
NOLLA ANTIMICROBIAL LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a foaming low alcohol content hand sanitizer with excellent long-lasting antimicrobial activity, enhanced stability, and skin-feel properties over alcohol-based sanitizers. The foam sanitizer leaves a smooth moisturized surface on the skin without leaving a sticky residue even after multiple applications. The foams and foamable compositions can be used for sanitizing and cleansing humans, animals, and other living objects, as well as for treating inanimate objects, such as surfaces, which become vehicles for communicable diseases. The composition is stable and can effectively eliminate virus, bacteria, yeast, and mold.

Problems solved by technology

There are disadvantages in alcohol-based sanitizers.
Thus, there is a lack of user comfortability and antimicrobial performance, especially long-term antimicrobial performance, is poor.
Also alcohol itself can cause drying and irritation of skin.
Alcohol is not effective against all known pathogens.
Silver based sanitizers suffer from stability problems, causing discoloration and performance issues.
Also colloidal and particle based silver sanitizers can agglomerate and cause concentration differences.
None of the earlier publications discloses foams or foamable compositions which are stable and which exhibit an extended antimicrobial effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

Foam with a Silver Concentration of 90 ppm

[0054]A foamable antimicrobial composition of the invention was provided by first preparing silver polymer. Commercially available polyethyleneimine (PEI) grade (Epomin P-1050, Nippon Shokubai, molecular weight 70 000 g / mol) with high molecular weight was chosen for its low toxicity values. 51.14 g of Epomin P-1050 grade contains 25.57 g of water which was removed before the silver polymer was prepared. The water phase disturbs the reaction with the silver salt and can lead to unstable silver polymer, for which reason water was removed at elevated temperature of 100° C. under high vacuum. 25.57 g of PEI was then dissolved in 118.83 g of isopropyl alcohol to obtain easily mixable polymer solution. The solution was reacted together with 3.57 g of fine grain grade of silver chloride (Silver (I) chloride, Colonial Metals, MESH 325) by mixing at room temperature until a clear colorless solution was formed.

[0055]The obtained solution was further r...

example 2

[0065]Similarly, an antimicrobial foaming composition of the invention was prepared by first dissolving 2.29 g of polyethyleneimine (Epomin SP-018, Nippon Shokubai, molecular weight 1 800) with 7.09 g of isopropyl alcohol under vigorous mixing. Said solution was reacted with 0.34 g of silver chloride (Silver (I) chloride, Colonial Metals, MESH 325) and a clear colorless solution was formed. Obtained solution was further reacted with 0.18 g of acid saccharin (E-954, Productos Aditivos) to stabilize the silver polymer. Said solution was diluted with 2.96 litres of deionized water under vigorous mixing to obtain a solution with a silver content of 84 ppm. 4.50 g of PEG-12 dimethicone (SM3350P, KCC Silicones) and 12.00 g of decyl glucoside (Oramix NS10, Seppic) was added to the solution to obtain foamable solution. For moisturizing effect and improved and skin feel 15.00 g of natural betaine (Betafin BP-20, DuPont) was added under stirring.

[0066]According to Turku University of Applied ...

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Abstract

Disinfection foam having low levels of alcohol, comprising at least water, foaming agent, and polymeric type silver ion source, and a method of manufacturing the same. The present antimicrobial foams are especially suitable for hand sanitizer foams, shaving foams, dry cleansing foams for full body, leave on shampoos, face cleansing foams and multipurpose dry cleaning

Description

FIELD OF INVENTION[0001]The invention relates to disinfection compositions. In particular, the present invention relates to novel multipurpose disinfection foams and foamable compositions. It also concerns methods of manufacturing such foams and compositions as well as to the uses thereof.BACKGROUND ART[0002]Alcohol hand sanitizers are widely accepted and used in the hospital and healthcare sectors. There are disadvantages in alcohol-based sanitizers. Thus, there is a lack of user comfortability and antimicrobial performance, especially long-term antimicrobial performance, is poor. There is no residual activity. Hands will be contaminated right after alcohol has evaporated, and the thickening agent used in the sanitizers will form a residual layer on the sanitized object, such as the user's hands, and offers a good substrate for microbial growth. Also alcohol itself can cause drying and irritation of skin. Alcohol is not effective against all known pathogens.[0003]Patent publication...

Claims

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Application Information

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IPC IPC(8): A61K8/19A01N55/02A61K8/40A61K8/04A61Q17/00A61K8/84
CPCA61K8/19A61Q17/005A61K8/84A61K2800/30A61K8/046A01N55/02A61K8/40A01N25/10A01N25/16A01N59/16A61K8/27C11D3/48
Inventor POYRY, JUHA-PEKKANIEMINEN, JYRI
Owner NOLLA ANTIMICROBIAL LTD
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