4results about How to "Strong ability to form" patented technology

The invention discloses 1000MPa-grade hydroelectric steel with optimized low-temperature toughness and a preparation method of the 1000MPa-grade hydroelectric steel, and belongs to the technical field of steel production. The 1000MPa-grade hydroelectric steel with the optimized low-temperature toughness is prepared from the following chemical components in percentage by weight: 0.03 to 0.09 percent of C, 0.80 to 1.40 percent of Mn, 0.10 to 0.15 percent of Si, 0.05 to 0.14 percent of Cu, less than or equal to 0.003 percent of S, less than or equal to 0.01 percent of P, 0.01 to 0.04 percent of Al, 0.03 to 0.10 percent of V, 0.03 to 0.06 percent of Cr, 0.3 to 0.65 percent of Mo, 0.001 to 0.002 percent of B, 0.01 to 0.018 percent of Ti, 0.015 to 0.025 percent of Nb, 0.18 to 0.60 percent of Ni and the balance of Fe and other inevitable impurities. The preparation method comprises a steel-making process, a heating process, a rough phosphorus removal process, a rolling process and a heat treatment process. By optimizing the chemical components and the preparation process of the 1000MPa-grade hydroelectric steel, the low-temperature toughness of the 1000MPa-grade hydroelectric steel is remarkably improved on the basis that the 1000MPa-grade hydroelectric steel with high strength is obtained, and the 1000MPa-grade hydroelectric steel is suitable for industrial application.

This invention discloses a class of polypeptide ligands that can specifically bind to and / or significantly promote the assembly of Holliday linkers and their applications, belonging to the field of biomedical technology. The general formula for the amino acid sequence of the polypeptide ligand is: AX₄BQX₃CXn, where A and B are each independently selected from any one of phenylalanine, tryptophan, tyrosine, lysine, and arginine; C is selected from any one of arginine and lysine; X represents any amino acid; and n is an integer ranging from 0 to 4. The advantages of this invention are: the polypeptide provided by this invention has a high affinity for Holliday linkers (HJs), a strong ability to promote HJ formation, and exhibits certain antitumor activity against human liver cancer cells A549.

The present application relates to the technical field of bioactive glass, in particular to a preparation method and application of strontium-magnesium-doped bioactive glass, on the basis of selecting suitable raw materials, the co-precipitation method is adopted, strontium element is doped, and magnesium oxide is compoundedly added, so that the prepared bioactive glass has regular properties, good dispersible spherical particles, faster and stronger hydroxyapatite formation capacity, faster ion release rate, and can release calcium, phosphorus and silicon ions in simulated body fluid, form more hydroxyapatite, promote the proliferation and stability of bone cells, and stimulate new bone formation. The strontium-magnesium-doped bioactive glass is used in cooperation with mineral trioxide aggregate (MTA), so that cell adhesion, expression of bioactive enzymes, activity of fibroblasts can be promoted, and the strontium-magnesium-doped bioactive glass can be applied to the repair of human bone and dental pulp tissue.

The present invention discloses a method for preparing a highly biologically active brushite / β-tricalcium phosphate bone tissue engineering scaffold, comprising the following steps: step 1, fully mixing malic acid-modified hydroxyapatite with β-tricalcium phosphate and anhydrous calcium dihydrogen phosphate to obtain brushite / β-tricalcium phosphate composite powder; step 2, uniformly mixing the brushite / β-tricalcium phosphate composite powder obtained in step 1 with a water-soluble non-aqueous liquid phase to obtain a precursor slurry; then blending the precursor slurry with distilled water to obtain a brushite / β-tricalcium phosphate composite slurry; step 3, extruding the brushite / β-tricalcium phosphate composite slurry obtained in step 2 at room temperature in one step by 3D printing to obtain a brushite / β-tricalcium phosphate bone tissue engineering scaffold. The present invention has the advantages of excellent biological activity and cell activity, and can be extruded at room temperature in one step by 3D printing.