Medicine for treating adiposis hepatica, and its preparation method

A fatty liver and drug technology, applied in the field of drugs for the treatment of fatty liver, can solve problems such as non-specificity and uncertain curative effect

Inactive Publication Date: 2009-07-01
JIANGSU SHENHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the treatment of Chinese patent medicines, the curative effect is mostly uncertain, and most of them are not specific, and there is no new traditional Chinese medicine drug with certain curative effect and specially for the treatment of this disease.

Method used

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  • Medicine for treating adiposis hepatica, and its preparation method
  • Medicine for treating adiposis hepatica, and its preparation method
  • Medicine for treating adiposis hepatica, and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0102] Weigh 1000g of Gynostemma pentaphyllum, 400g of Salvia miltiorrhiza, 1000g of Polygonum cuspidatum, 300g of dried lotus leaves, and 600g of capillary wormwood, add water to decoct three times, add 6 times the amount of water for the first time, soak for 30 minutes, extract for 1 hour, filter, and use 3 times the filter residue in turn , 3 times the amount of water and extract each for 1 hour, combine all the filtrates, concentrate under reduced pressure to an extract whose specific gravity is 1.23-1.25 (50°C), slowly add 2 times the amount of 95% ethanol under stirring, separate the supernatant, and recover Ethanol and concentrated under reduced pressure to a relative density of 1.20-1.22 (70-80°C) extract, dried under reduced pressure at 70°C, superfinely pulverized the dry extract with soybean oil containing appropriate amount of beeswax, made into a paste, pressed into soft capsules, and granulated to obtain final product.

Embodiment 2

[0104] Weigh 1500g of Gynostemma pentaphyllum, 500g of Salvia miltiorrhiza, 1000g of Polygonum cuspidatum, 300g of dried lotus leaf, and 600g of capillary root, add water to decoct three times, add 6 times the amount of water for the first time, soak for 30 minutes, extract for 1 hour, filter, and use 3 times the filter residue in turn , 3 times the amount of water and extract each for 1 hour, combine all the filtrates, concentrate under reduced pressure to an extract whose specific gravity is 1.23-1.25 (50°C), slowly add 2 times the amount of 95% ethanol under stirring, separate the supernatant, and recover Ethanol and concentrated under reduced pressure to a relative density of 1.20-1.22 (70-80°C) extract, dried under reduced pressure at 75°C, superfinely pulverized the dry extract with soybean oil containing an appropriate amount of beeswax, made a paste, pressed into soft capsules, and granulated to obtain final product.

Embodiment 3

[0106]Weigh 1500g of Jiaogulan, 500g of Danshen, 1500g of Polygonum cuspidatum, 400g of dried lotus leaf, and 700g of capillary, add water to decoct three times, add 6 times the amount of water for the first time, soak for 30 minutes, extract for 1.5 hours, filter, and use 3 times the filter residue in turn , 3 times the amount of water and extract each for 1-5 hours, combine all the filtrates, concentrate under reduced pressure to an extract whose specific gravity is 1.23-1.25 (50°C), slowly add 2 times the amount of 95% ethanol under stirring, and take the supernatant , recovering ethanol and concentrating under reduced pressure into an extract with a relative density of 1.20-1.22 (70-80°C), drying under reduced pressure at 75°C, and superfinely pulverizing the dry extract with soybean oil containing an appropriate amount of beeswax to make a paste, Compressed into soft capsules and granulated to obtain the final product.

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PUM

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Abstract

The invention discloses a medicine for treating fatty liver, which is prepared from the following raw materials in parts by weight: 10-30 parts of Jiaogulan, 4-12 parts of Salvia Miltiorrhiza, 10-30 parts of Polygonum cuspidatum, 3-9 parts of dried lotus leaves and Capillaris 6-12 parts. The invention provides the therapeutic drug with the effects of clearing liver, promoting dampness, promoting blood circulation and removing blood stasis for patients with fatty liver. In addition, the invention also discloses a preparation method of the soft capsule of the medicine.

Description

technical field [0001] The invention relates to a medicine for treating fatty liver and a preparation method thereof. Background technique [0002] Fatty liver is a fatty change in the liver caused by a variety of reasons. Its incidence is closely related to age, gender, blood lipids, high blood pressure, obesity, etc. Alcoholism, high-fat protein diet, extra meals before going to bed, and excessive sleep are the main causes of fatty liver disease. major risk factors for the liver. Due to changes in people's living conditions and lifestyles, alcoholism, overnutrition obesity, diabetes and drug-induced damage have become important causes of fatty liver. The prevalence of fatty liver and related diseases has increased significantly. [0003] Fatty liver is often treated with lipid-lowering drugs. Since the 1980s, blood lipid-lowering drugs have been constantly updated, but clinical practice has found that most chemically synthesized blood-lipid-lowering drugs have unsatisfa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/62A61K36/53A61K36/424A61K36/28A61K36/39A61K9/48A61P1/16
Inventor 季光安红梅郑培永
Owner JIANGSU SHENHUA PHARMA
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