222results about How to "Significant blood pressure lowering effect" patented technology

The invention provides a cassia obtusifolia tea bag with functions of weight reduction, hypotension and hypoglycemic effect, which is characterized in that the production process comprises the following steps: washing, cleaning and drying the cassia obtusifolia stem, leaf and grain, crushing by a pulverizer to 280 meshes, uniformly stirring, packing, disinfecting to obtain the cassia obtusifolia tea bag with functions of lipid lowering, hypotension and hypoglycemic effect. The optimal composition and the weight part ratio of the tea bag are: 40-60 parts of dried cassia obtusifolia stem, leaf and grain, 10 parts of dried lotus leaf, 5 parts of haw, 5 parts of dried balsam pear, 5 parts of Chinese wolfberry, 10 parts of Pu'er tea, 10 parts of cassia seed, 5 parts of mulberry leaf, 5 parts of folium apocyni veneti, 5 parts of Chinese yam as medicine, 3 parts of rhubarb, 2 parts of chrysanthemum, 2 parts of honeysuckle flower, 1 part of boat-fruited sterculia, 5 parts of cassia seed, 5 parts of kudzu root and 10 parts of additive. The additive is composed of fatty acid sucrose ester, xylitol, mannitol crystal, natural menthol, citric acid, trisodium phosphate, sodium saccharin and steviosid; the above components are carried out the processes of crushing, mixing, uniformly stirring, packing and disinfecting to obtain the tea bag.

The invention provides a health-care product for reducing blood sugar and blood pressure, relaxing bowels, losing weight, resisting fatigue and improving sexual function. The product comprises okra, pollen pini, tartary buckwheat, medicinal yam, soy isoflavone, soyasaponin and 10 parts of additional component, wherein the additional component comprises xylitol, mannitol crystal and natural menthol in a ratio of 1: 1: 1. The product is produced by the following steps of: 1, weighing the components in the ratio, and crushing in an ultrafine crusher to obtain powder of 200 meshes for later use; stir-frying the tartary buckwheat; and 2, weighing the additional component in a powder shape according to the proportion, mixing the powder, stirring uniformly, drying at the temperature of 60 DEG C under reduced pressure, sterilizing, thus obtaining a semi-finished product of the health-care product for reducing the blood sugar and the blood pressure, relaxing the bowels, losing the weight, resisting the fatigue and improving the sexual function, and preparing granules, pills, tea bags, solid granules, liquid beverage, tablets, effervescent tablets, biscuit or thick soup from the semi-finished product of the health-care product or adding the semi-finished product into capsules to prepare capsules facilitating carrying.

A method for preparing a goat milk beverage containing ACE (Angiotensin Converting Enzyme) inhibitory peptide comprises the following steps of: cooling, centrifuging and fatting reconstituted goat milk, thereby obtaining skimmed milk; preparing casein from the skimmed milk by an isoelectric precipitation method, and obtaining polypeptide powder through enzymolysis; and mixing polypeptide powder with reconstituted goat milk, concentrated fruit juice, polypeptide powder, cane sugar, citric acid, beta-cyclodextrin, purified water and the like to obtain the goat milk beverage containing ACE inhibitory peptide. The goat milk beverage containing ACE inhibitory peptide prepared by the method provided by the invention contains the ACE inhibitory peptide and thereby has obvious effect of reducing blood pressure; if the hyperpietic drinks the goat milk beverage for a long time, the blood pressure of the hyperpietic can be reduced; and the goat milk beverage is mild in properties without side effect on people of normal blood pressure; and the goat milk beverage containing ACE inhibitory peptide has various effects of immunological activity, and prompting digestive absorption and losing weight, and the like.

The invention relates to an application of a seaweed polypeptide in preparing a health-care product for reducing blood fat and blood sugar as well as a beverage containing the polypeptide for reducing the blood fat and the blood sugar. The seaweed polypeptide is prepared by the following steps of: milling a mixture of immersed porphyra haitanensis and water through a colloid mill to obtain porphyra haitanensis slurry; adopting AS.1398 neutral protease to carry out enzymolysis on the porphyra haitanensis slurry for 5-10 hours under the conditions that the temperature is 45-55 DEG C, the pH (Potential of Hydrogen) is 7.2-7.8, the enzyme adding amount E/S is 8000-12000 U/g and the weight/volume ratio concentration of a substrate is 3-7%, so as to obtain an enzymolysis solution; centrifuging the enzymolysis solution and collecting liquid supernatant; and carrying out ultra-filtering separation on the liquid supernatant to obtain an active component with the molecular weight of less than 10000 Da. An animal experiment shows that agars are subjected to biological enzymolysis to obtain the seaweed polypeptide which has the obvious effects of reducing the blood fat, the blood sugar and blood pressure; and after the seaweed polypeptide is taken for a long period, the weight can be prevented from too fast increase and the happening possibility of arteriosclerosis can be reduced.

The invention discloses traditional Chinese medicine heal-care tea with the effects of moistening lung and lowering blood pressure, overcoming the defects of poor taste and unobvious blood pressure lowering effect of the traditional Chinese medicine heal-care tea in the prior art. The traditional Chinese medicine heal-care tea comprises the following Chinese medical herbs: chrysanthemums, apocynum venetum, selfheal, honey mulberry leaves, gynostemma pentaphyllum, lofty wallich wedelia herbs, ligusticum wallichii, lofty hedgehog hydnum, lofty hawthorns, and the like. A preparation method of the traditional Chinese medicine heal-care tea comprises the following steps of: mixing the Chinese medical herbs and then grinding or respectively grinding the Chinese medical herbs and then mixing; carrying out germicidal treatment; and placing into a brewing bag made of tea filter paper for brewing drinking. The selected raw Chinese medical herbs jointly act and have the effects of clearing heat and moistening the lung, activating blood and dissolving stasis and obviously lowering blood pressure ; and in addition, after the traditional Chinese medicine heal-care tea is drunk for a long time, symptoms, i.e. giddiness, headaches, dizziness, insomnia, frightened epilepsy, convulsion, and the like which are caused by blood pressure diseases, are obviously relieved or dispelled.

The invention provides an inflatedfruit senna seed slimming, lipid reducing, pressure lowering and glucose lowering biscuit. The biscuit is developed and is mainly designed for vast 'three-tall' patients in a rising trend, and the biscuit is prepared by taking inflatedfruit senna seed powder as major ingredient and adding auxiliary material used for lowering sugar, lowering pressure and reducing lipid and then adding additive. The biscuit has the effects of slimming, lowering pressure, lowering glucose of a diabetic patient and reducing complication and is a health care food for the diabetic patient.

The invention provides a mung bean yoghourt product having the function of reducing the blood pressure and a preparation method thereof. The mung bean yoghourt product is prepared from mung bean extract and milk powder, wherein the mung bean extract is prepared by soaking mung beans in a glutamic acid solution; and the mung bean extract accounts for 80 to 90 weight percent, and the milk powder accounts for 10 to 20 weight percent. The preparation method comprises: soaking the mung beans in the glutamic acid solution, accelerating germination of the mung beans, and performing seed coat removal,homogenizing and high-temperature amylase treatment to obtain the mung bean extract; adding skim milk powder into the mung bean extract, performing mixing and homogenization treatment, adding protease for enzymolysis, and obtaining a fermentation substrate; and performing enzyme killing, sterilization, cooling and lactobacillus inoculation on the fermentation substrate, and performing fermentation on the fermentation substrate to prepare the mung bean yoghourt product. The mung bean yoghourt product not only is rich in GABA but also contains ACE inhibitory peptide, has good effect of reducingthe blood pressure, not only can be directly used for preparing related health food but also can be used as a functional composition and added into other health products, and has wide application prospect.

The present invention provides an isoquinoline-6-sulfonamide derivative that is useful as a novel pharmaceutical agent. The present invention provides an isoquinoline-6-sulfonamide derivative represented by Formula (1), a salt thereof, or a solvate of the derivative or the salt: wherein X and Y each independently represent a direct bond, NH, CH-CH, O, or S; R1 and R2 each independently represent a hydrogen atom, a halogen atom, a cyano group, an alkyl group, or the like; R3 and R4 each independently represent a hydrogen atom, an alkyl group, or the like, or R3 and R4 together form an alkylene group or an alkenylene group, which may be bridged between two carbon atoms to an arbitrary position; and l, m, and n represent an integer number of 1 to 4.

The invention discloses an earthworm protein for reducing blood sugar and blood pressure and eliminating diabetic complications. The earthworm protein is prepared by adopting the following steps of: 1) cleaning earthworms, namely, selecting live earthworms, removing impurities and dead earthworms, putting the live earthworms into water of which the PH value is 4 to 5.8 for 10 to 15 minutes, meanwhile, adding 50 g of salt, leaching the cleaned live earthworms, and flushing the live earthworms by using warm water of 28 DEG C to remove redundant moisture and impurities on the outer surfaces; 2) pulping; 3) filtering or centrifuging the homogenate obtained in the step 2) to remove rough residue therein, and filtering the residue removed homogenate to obtain clear liquor, wherein each milliliter of the clear liquor contains more than 180 enzyme activity units; putting the clear liquor into a disinfected container, injecting high-pressure CO2 gas, mechanically and fully stirring the clear liquor to be treated for 3 to 8 minutes, and releasing pressure through a conduit, wherein the solubility of CO2 is quickly reduced after the pressure is reduced; then filtering to remove impurities, and settling for 12 hours to obtain supernate; and 4) freeze-drying, namely drying the supernate in a freeze drier of 28 DEG C below zero to obtain a powdery product, wherein each milligram of the product contains 2,000 to 3,000 enzyme activity units.

The invention discloses a method for producing bioactive peptide with a high blood pressure resistant function from casein, which comprises the steps of enzymolysis reaction and the desalting of zymolyte, wherein, zymolyte in the enzymolysis reaction is casein aqueous solution; prolease Alcalase is selected as enzyme; the consumption of the enzyme is 0.072 AU/g bioactive peptide; the temperature of the whole reaction process is controlled to be 55 DEG C to 60 DEG C; the pH value is between 8.4 to 8.6; the enzymolysis time is 5 to 6 hours. The invention also discloses the casein bioactive peptide prepared through the method. The bioactive peptide has good high blood pressure resistant function, and can be used to prepare high blood pressure resistant drinks, food or medicine.

The invention relates to a blood pressure-reducing low sodium salt added with potassium chloride and chitosan oligosaccharide and a production method of the blood pressure-reducing low sodium salt. The blood pressure-reducing low sodium salt comprises the following components in percent by weight of 60-83 percent of edible salt, 13-30 percent of potassium chloride, 3-9 percent of chitosan oligosaccharide and 0.1-1.0 percent of silica. The blood pressure-reducing low sodium salt provided by the invention has the advantages that the chitosan oligosaccharide is fused in the edible salt, so that people can take in a proper amount of chitosan oligosaccharide, the blood pressure reducing effect is far higher than that of the low sodium salt on the market; the immune modulating function of a human body can be effectively enhanced, hypertension, hyperlipidemia and hyperglycemia are reduced; according to the condition that the crowd in China is lack of potassium, the adding quantity of the potassium chloride is properly reduced, and the cost is saved under the condition of meeting the demand of replenishing the potassium in the human body; by utilizing a proper quantity of powdery refined salt and silica and other products, the quality problems of layering and blocking and the like are effectively avoided; and raw materials and auxiliary materials all belong to the food grade and are safe without side effects.

The present invention belongs to the technical field of medicine, and particularly relates to an imidazole carboxylic acid derivative represented by a general formula (I), a pharmaceutically acceptable salt, a stereoisomer, or a deuterated substance thereof, wherein R1, R2, R3, X, L , C<1> and C<2> are defined in the description. The present invention further relates to a preparation method for the compounds, pharmaceutical preparations containing the compounds, and uses of the compounds in preparation of drugs for treatment and/or prevention of cardiovascular diseases. The general formula (I) is shown in the description.

The invention discloses a plant water, a plant water beverage, a preparation method of the plant water, and a preparation method of the plant water beverage. The preparation method of the plant water comprises the following steps: 1, carefully choosing plant water raw materials, and cleaning; 2, preparing a plant water normal juice; 3, carrying out cold enzyme killing and color protecting treatment on the normal juice; 4, carrying out enzymatic hydrolysis treatment; 5, carrying out fine filtration and hollow filtration; 6, decoloring; and 7, carrying out cold disinfection. The preparation method of the plant water is characterized in that an ultrafiltration technology is adopted after fine filtration in order to decolor, so the plant water and the plant water beverage prepared in the invention have high clarification degree, the flavor of a fruit and vegetable juice is well kept, nutritional components of Vc are well reserved, and soluble proteins are effectively intercepted, thereby the finished plant water and the finished plant water beverage prepared in the invention have small browning degree and prolonged shelf life. The plant water and the plant water beverage prepared in the invention completely reserve nutritional values and health functions of fresh fruits and vegetables, and have the health functions of clearing heat and removing internal heat, promoting body fluid production and quenching thirst, moistening lung, removing fat and lowering blood pressure, detoxifying, relieving alcohol effect, promoting urination and relieving swelling, and reducing weight.

The invention discloses an antihypertensive peptide P16 which has the amino acid sequence shown as SEQ IDNo.1. The antihypertensive peptide P16 is clear and definite in structure and good in antihypertensive activity. The invention further discloses a preparation method of the antihypertensive peptide P16. The preparation method has a compact process and realizes the standardization of the quality of the antihypertensive peptide P16. The invention further discloses an application of the antihypertensive peptide P16 in preparation of a medicine or a food with an antihypertensive function.

The invention provides inflatedfruit senna seed instant nutritious coffee powder and coffee for losing weight and reducing fat, pressure and sugar, and a production process thereof. The coffee powder and the coffee are prepared by the following steps of: crushing inflatedfruit senna seeds which are cleaned and dried into particles with the particle size of 400-500 meshes by using an ultra-micro pulverizer, adding 100DEG C distilled water, fully stirring uniformly, filtering by using filter paper or lint, settling for 15 minutes, and taking an upper-layer concentrated coffee extracting solution to obtain the nutritious coffee; and injecting the concentrated coffee extracting solution by using a hot air injector to evaporate water in a coffee extract and remain a solidified and dried coffeeblock, cooling, and grinding by using a commercial coffee grinder to obtain the inflatedfruit senna seed instant nutritious coffee powder for losing weight and reducing fat, pressure and sugar.

The invention relates to a fermented milk product with a blood pressure reducing function and a preparation method thereof and belongs to the technical field of milk product processing. Water buffalo milk is adopted as a raw material and combined with saccharose, a water buffalo milk antihypertensive peptide base material, taurine and a lactic acid bacterium strain, and the fermented milk product with the blood pressure reducing function is prepared. The preparation method of the fermented milk product is simple, and the prepared yogurt is strong in milk fragrance, creamy in texture, fine and smooth in taste and rich in nutrition. All nutritional value of the water buffalo milk can be kept, meanwhile, the blood pressure reducing effect is improved, and the healthcare effect of the fermented milk product is improved. The prepared fermented milk product is free of any additive, long in shelf life, safe, environmentally friendly and healthy.

The invention discloses an immunity-enhancing health nutritional composition, as well as a preparation method and application thereof. The immunity-enhancing health nutritional composition comprises the following raw materials by weight: 20 to 40 parts of sprouted highland barley flour, 5 to 15 parts of oat meal, 10 to 30 parts of milk powder, 1 to 5 parts of yak bone meal, 5 to 15 parts of duck wheat, 0.1 to 1 part of ginseng powder, 2 to 8 parts of fructo-oligosaccharide, 5 to 15 parts of yam powder, 1 to 10 parts of golden silk jujube powder, 0.1 to 1 parts of haematococcus pluvialis, and 0.1 to 1 part of fructus momordicae powder. The immunity-enhancing health nutritional composition can have an immunity-enhancing efficacy according to the requirements of modern consumers, and has the advantages that the raw materials are natural; no side effect is caused; the suitability for the middle-aged and elderly as well as crowds of which the immunities are required to be enhanced is very high; the taste is good. Therefore, the immunity-enhancing health nutritional composition achieves popularity.

The invention discloses a health care product for cleaning colon and promoting defecation, and eliminating toxin and beautifying skin and a preparation method of same. The health care product is mainly prepared from the following raw materials by the following steps: smashing cleaned and baked inflatedfruit senna seed, baked flower, and baked inflatedfruit senna stem leaf by an ultra-micro pulverizer into 360 to 450 meshes, then airing and sterilizing the obtained product to obtain inflatedfruit senna powder; and filling the inflatedfruit senna powder into capsules to prepare hard and soft capsules for eliminating toxin and beautifying skin. The Chinese herbal medicaments are organically combined, perform treatment based on the syndrome differentiation, are mutually supported, and have the effects of eliminating toxin and beautifying skin, lubricating bowel and promoting defecation, eliminating halitosis and clearing toxicants accumulated at gastrointestinal tracts, so as to achieve the purposes of cleaning colon and promoting defecation, and treating constipation. More importantly, the health care product is very gentle and can solve constipation without causing diarrhea. Meanwhile, the product is selected from natural raw materials which are free from pesticide residue pollution, and has no preservatives to achieve the effects of clearing heat and refreshing, cooling down and cleaning colon, repressing the liver and improving eyesight, resisting cancer and aging, and strengthening the immunity for a patient; and furthermore, the product has no toxin or side effect after being taken for a long time and improves the body immunity.