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Method for treating coronary heart disease and angina pectoris

Coronary heart disease angina pectoris and drug technology, applied in the field of medicine

Inactive Publication Date: 2009-11-04
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] At present, there is no report on the use of the interaction and compatibility of Trichosanthes, Curcuma, Shichangpu and Danshen to prepare medicines for treating angina pectoris of coronary heart disease.

Method used

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  • Method for treating coronary heart disease and angina pectoris
  • Method for treating coronary heart disease and angina pectoris

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment 1: the preparation of pharmaceutical tablet of the present invention

[0067] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0068] Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosant...

Embodiment 2

[0069] Embodiment 2: the preparation of medicine capsule of the present invention

[0070] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0071]Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosanthes T...

Embodiment 3

[0072] Embodiment 3: the preparation of pharmaceutical granule of the present invention

[0073] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0074] Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosa...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and discloses a medicine for coronary heart disease angina pectoris and a preparation method thereof. The medicine is mainly prepared from Trichosanthes trichosanthes, Curcuma curcuma, Shichangpu and Salvia miltiorrhiza in a certain weight ratio. It can be made into any clinically or pharmaceutically acceptable dosage form, preferably an oral preparation. The drug has the effects of regulating qi and broadening the chest, dispelling turbidity and relieving stagnation, dispelling blood stasis and dredging collaterals. It can be used for coronary heart disease angina pectoris, symptoms such as chest tightness and chest pain, cough and wheezing, palpitation, shortness of breath, and mental fatigue.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine and relates to a medicine for coronary heart disease angina pectoris, in particular to a medicine for coronary heart disease angina pectoris made from Chinese herbal medicine. 2. Background technology [0002] Coronary heart disease angina pectoris is a common type of coronary heart disease caused by paroxysmal pain or discomfort in the chest caused by coronary atherosclerosis leading to lumen stenosis or coronary artery spasm, myocardial ischemia and hypoxia. In recent years, the incidence of coronary heart disease angina pectoris has increased significantly, and its proportion in heart disease has jumped to the first place. [0003] The main causes of this disease are long-term improper diet, old age, physical weakness, internal invasion of cold pathogens, and emotional disorders, which are mostly proximate causes or inducements. Excessive physical or mental work, on the basis of insufficie...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K36/888A61K36/53A61K36/428A61P9/10
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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