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Medicine for curing gout and its preparing method

A medicine and technology for gout, applied in the field of medicine for treating gout and its preparation, can solve the problems of drug toxicity and side effects, and achieve the effects of clear drug effect, reasonable prescription, and small clinical dosage

Active Publication Date: 2010-01-13
CHANGCHUN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a medicine for treating gout and a preparation method thereof, so as to solve the problem that the current medicine has certain toxic and side effects

Method used

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  • Medicine for curing gout and its preparing method
  • Medicine for curing gout and its preparing method
  • Medicine for curing gout and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The preparation of embodiment 1 granule of the present invention

[0024] Smilax 1600 grams, Gentiana chinensis 650 grams, corn silk 1350 grams, comfrey 300 grams.

[0025] The above four flavors, 1 / 3 of Gentiana and 1 / 3 of Comfrey are crushed into fine powder, and the remaining Gentiana and Comfrey are refluxed and extracted twice with 65% ethanol for 2 hours and 1 hour respectively, and the extracts are combined , placed at 4°C for 24 hours, filtered, the filtrate was decompressed to recover ethanol and concentrated to 40°C-50°C to measure the thick paste with a relative density of 1.30-1.35, and dried; corn silk and Smilax smilax were decocted twice with 25 times the amount of medicinal materials , the time is 2 hours and 1 hour respectively, the decoctions are combined, placed at 4°C for 24 hours, filtered, the filtrate is concentrated to 40°C-50°C to measure a thick paste with a relative density of 1.30-1.35, and dried; Mix with comfrey fine powder, pulverize into...

Embodiment 2

[0026] The preparation of embodiment 2 pills of the present invention

[0027] Smilax 1800 grams, Gentiana chinensis 720 grams, corn silk 1440 grams, comfrey 360 grams.

[0028] The above four flavors, 1 / 3 of Gentiana and 1 / 3 of Comfrey are crushed into fine powder; the remaining Gentiana and Comfrey add 8 times the amount of medicinal materials and 70% ethanol to reflux and extract 3 times, the time is 2, 2 and 1 hour in sequence, and the combined extraction liquid, placed at 4°C for 24 hours, filtered, and the filtrate was decompressed to recover ethanol and concentrated to a thick paste with a relative density of 1.30 to 1.35 at 40°C to 50°C, and dried; corn silk and Smilax smilax were decocted with 30 times the amount of medicinal materials in water for 2 Once, each time for 2 hours, combine the decoction, place it at 4°C for 24 hours, filter, concentrate the filtrate to a thick paste with a relative density of 1.30 to 1.35 at 40°C to 50°C, and dry it; mix the above dry ex...

Embodiment 3

[0029] The preparation of embodiment 3 tablet of the present invention

[0030] Smilax 2000 grams, Gentiana 750 grams, corn silk 1500 grams, comfrey 400 grams.

[0031] The above four flavors, 1 / 3 of Gentiana and 1 / 3 of Comfrey are crushed into fine powder, and the remaining Gentiana and Comfrey are added with 9 times the amount of medicinal materials and 60% ethanol is reflux extracted for 3 times, the time is 2, 2 and 1 hour respectively, and combined extraction liquid, placed at 4°C for 24 hours, filtered, and the filtrate was decompressed to recover ethanol and concentrated to a thick paste with a relative density of 1.30 to 1.35 at 40°C to 50°C, and dried; corn silk and Smilax smilax were decocted with 28 times the amount of medicinal materials in water for 2 Once, each time for 2 hours, combine the decoction, place it at 4°C for 24 hours, filter, concentrate the filtrate to a thick paste with a relative density of 1.30 to 1.35 at 40°C to 50°C, and dry it; mix the above d...

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Abstract

The invention relates to a medicament for treating gout and process for preparation, which is prepared from the following raw material herbs (by weight portion): rhizome smilacis glabrae 1600-2000 parts, large-leaf gentian root 650-750 parts, corn stigma 1350-1500 parts and alkanna tinctoria 300-400 parts.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a medicine for treating gout and a preparation method thereof. Background technique [0002] Modern medicine believes that uric acid is the final product of nucleic acid-based purine catabolism, which can be divided into endogenous and exogenous. The metabolism of endogenous purine in the body is regulated by hypoxanthine-guanine phosphoribosyltransferase, xanthine converting enzyme and phosphoribosyl pyrophosphate amidotransferase to metabolize into uric acid. Exogenous is that purine in food is metabolized into uric acid in the body. Uric acid is mainly excreted in urine by the kidneys. If the body produces too much uric acid or excretes less from the kidneys (urine), it will cause blood uric acid to rise and become hyperuricemia. In the case of prolonged hyperuricemia, blood urate is precipitated or precipitated in the tissues, leading to gout. Gout i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P19/06
Inventor 陈心智赵悦黄晓巍衣春光臧丽馨邓毅峰于秀华欧喜燕周鸣王明星付春赵虹
Owner CHANGCHUN UNIV OF CHINESE MEDICINE
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