47results about How to "Improve formulation quality" patented technology

The invention provides a high-purity antibiotic medicinal compound, and in particular relates to a method for refining beta-lactam penicillin antibiotic medicinal compounds. In the method, an acid-base pH method and a macroporous absorption resin method are effectively combined; and beta-lactam penicillin antibiotic medicinal compounds are refined and purified under specific process parameters to prepare over 99.9 percent high-purity beta-lactam penicillin antibiotic medicinal compounds with yield over 90 percent, so that unexpected purification effect is achieved. The high-purity beta-lactam penicillin antibiotic medicinal compounds are prepared by the method, so that the stability of corresponding preparations thereof and clinical application effect can be improved. The method is simple, has low cost, is easily for operation, and is applicable to large-scale industrial production.

The invention discloses a sand production line. The sand production line comprises a sand feeding hopper, a composite feeding machine, a primary crusher, a secondary crusher, a cleaning device, a grading device and a classifying stock bin, wherein a discharging port of the sand feeding hopper is connected to the feeding end of the composite feeding machine, the discharging end of the composite feeding machine is connected to a feeding hopper I of the primary crusher, a collecting hopper I of the primary crusher is connected to a feeding hopper II of the secondary crusher through a conveying belt, a collecting hopper II of the secondary crusher is connected to the cleaning device through a conveying belt, the cleaning device is connected to the grading device through a conveying belt, and the grading device is connected to the classifying stock bin through a conveying belt. According to the sand production line, by means of the sand feeding hopper, the composite feeding machine, the primary crusher, the secondary crusher, the cleaning device, the grading device and the classifying stock bin, automatic and continuous sand production can be realized, the production efficiency is high, the labor intensity can be reduced, and automatic monitoring and unattended operation can be realized.

The invention discloses a making method of tri-gold dispersing pill and a preparation method, which is characterized by the following: decompressing to condense the boiled raw material; spraying to dry condensate; adding fitful micro-crystal cellulose, micro-powder silica gel and sodium carboxymethylstarch through wet-method to grain or adding fitful quantity of micro-crystal cellulose to grain further; grinding the needed particle; pressing; obtaining the product. The preparation method not only can prepare tri-gold dispersing pill with characters including easy taken, fast absorption and high bioavailability, and all indexes are up to the specification in chinese pharmacopoeia; and in condition of the same crude drug amount, the amount of the effective constituent asiaticoside is much higher than the amount of tri-gold capsule.

The invention relates to a preparation method for a traditional Chinese medicine oral preparation with traditional Chinese medicines as main materials. One, two or three raw medicines of the medicine composites are shattered and sifted out; the other non-shattering raw medicines are grouped or not grouped, decocted and extracted with water, concentrated and refined; the shattering and sifting rawmedicine powder is used as basic charge by added in one or two components of proper starch, dextrine and micro silica gel, and water extract is injected for a one-step granulation for troche, capsule, pill, granular formulation and other formulations. The invention has a feasible technology, decreases the impurity in the extract and the loss of the active ingredient in the extraction process, thegranulation is more convenient, the grain is more uniform, the subsequent working procedures of tabletting and enpsulation are easier; the prepared traditional Chinese medicine compound preparation for curing the gout disease has the advantages of high preparation quality, low clinical dose and other advantages; each index of the product is fully qualified, and the quality of the product is improved greatly.

The invention relates to a preparation device, in particular to an electrolyte preparation device. A technical problem to be solved in the invention is to provide an electrolyte preparation device which is easy to control and good in preparation quality. In order to solve the technical problem above, the electrolyte preparation device comprises a mounting frame, a cylinder body, a discharge pipe,a valve, a piston, a nut, guide sleeves, guide rods, a feed hopper, a first bearing, a first rotating shaft, a first gear, and a mounting plate, wherein the cylinder body is arranged in the middle ofthe upper wall of the mounting frame; the discharge pipe is arranged at the lower part of the right wall of the cylinder body; the valve is arranged on the discharge pipe; the piston is arranged at the lower part in the cylinder body and is in fit with the cylinder body; the nut is arranged in the middle of the piston; the guide sleeves are arranged symmetrically on the lower wall of the cylinderbody in the left-right direction; and the guide rods are arranged in the guide sleeves in a sleeving manner. The device has effects of proportion control easiness and good preparation quality. In thedevice, the piston can move up and down through continuous clockwise-anticlockwise rotation of blades, and the piston and the blades are matched with each other, so that the preparation quality of electrolyte is relatively good.

The invention discloses a gravel production gradation adjustment device. The gravel production gradation adjustment device comprises a grading screen, and the grading screen comprises multiple layers of screens; the screen I of which the mesh diameter is 4.75 mm, the screen II of which the mesh diameter is 3 mm, the screen III of which the mesh diameter is 1.25 mm, the screen IV of which the mesh diameter is 0.25 mm, the screen V of which the mesh diameter is 0.16 mm and the screen VI of which the mesh diameter is 0.075 mm are sequentially arranged from top to bottom; the discharge ends of the screens are connected to material collection hoppers; each material collection hopper is connected to one bin through a pipeline; weighing devices are arranged at discharge openings of the bins; a belt conveyer is arranged in front of the weighing devices; and the discharge end of the belt conveyer is connected to a stirring machine. According to the gravel production gradation adjustment device, classification of six-grade stone of which the particle sizes are 0 mm to 0.075 mm, 0.075 mm to 0.16 mm, 0.16 mm to 0.25 mm, 0.25 mm to 1.25 mm, 1.25 mm to 3 mm, and 3 mm to 4.75 mm can be achieved, weighing is achieved through the weighing devices, finally, stone of the required gradation is matched according to different utilization requirements and is put into the stirring machine to be stirred and mixed, stone powder of the required gradation can be better prepared, preparation quality of stone powder is improved, selectivity is high, and gradation adjustment can be effectively controlled.

The invention belongs to the technical field of machine manufacturing, relates to a machine tool cutting fluid rapid preparation device for machine manufacturing, and aims to adjust the hardness of water. The device comprises a preparation box; a feeding box with low water hardness and a feeding box with high water hardness are arranged on the outer wall of the top of the preparation box; naturalcoral sand and a cation exchange resin layer are arranged on the inner walls of the feeding box with low water hardness and the feeding box with high water hardness respectively, a conveying belt anda second conveying belt are arranged on the two sides of the inner wall of the preparation box respectively, and scrapers distributed at equal intervals are arranged on the outer walls of one sides ofthe conveying belt and the second conveying belt respectively. By arranging the feeding box with low water hardness, the natural coral sand, the feeding box with low water hardness, the cation exchange resin layer, the conveying belt, the second conveying belt, the scrapers and a cleaning brush, different feeding boxes are selected for feeding according to the hardness value of water, the hardness of the water can be improved or reduced to a certain extent, and the preparation quality of a cutting fluid is improved.

A Chinese medicine in the form of injection of any orally taken form for treating the infection of respiratory tract and digestive system, improving immunity, and preventing tumor is proportionally prepared from Asiatic moonseed rhizome or its extract and the 14-dehydroxy-11,12-didehydro andrographolide-3,19-semiester succinate or its pharmacologically acceptable salt.

The invention discloses a pigment preparation device for drawing oil painting. Through cooperative use of a heat preservation layer, a heating layer and a temperature controller, the interior of a machine body is kept at a stable temperature all the time, and the pigment preparation quality can be improved; through the arrangement of a weighing device, after the pigment is prepared, the prepared pigment can be directly weighed and equally divided, subsequent production is facilitated, and the production efficiency is improved; and through the arrangement of a cleaning device, after the pigmentis prepared, the interior of a preparation cylinder can be conveniently cleaned, the pigment can be conveniently used when the pigment is prepared again, and the labor intensity of workers is reduced. According to the pigment preparation device for drawing the oil paintings provided by the invention, a fine ingredient adding assembly and a cleaning assembly are integrally installed together and extend into the machine body, space is saved, meanwhile, holes on a machine cover can be reduced, and through the arrangement of a visual window, a colorimetric bar and a control panel, colors can be accurately compared, the comparison effect is improved, and the accuracy of the prepared pigment is guaranteed.

The invention discloses a benvitimod impurity as well as a preparation method and application thereof. The prepared benvitimod impurity is high in purity and can be used as an impurity reference substance in benvitimodbulk drug or preparation detection, accurate positioning of the impurity 6-methyl-5-[(E)-2-styryl]-2-isopropyl-1,3-benzenediol in production quality control of benvitimod is improved, control over the impurity is enhanced, and the quality of the benvitimod preparation is improved, so that the safety and the effectiveness of the benvitimod preparation in clinical use are ensured.

The invention relates to a conveying device and method of liquid crystal display glass materials for improving the whole uniformity of auxiliary materials, and the device comprises electronic scale, where the electronic scale is connected through wearable pipeline with a collection bunker, the lower part of the collection bunker is provided with material discharge paddle and vibrating device, the collection bunker is connected with a material mixing machine through the material discharge paddle; firstly after weighed by the electronic scale, the raw materials are discharged in sequence and then enter through the wearable pipeline into the collection bunker, and as discharging, a part of the quartz powder is discharged from the raw materials, other raw materials are then discharged then, and finally the remaining quartz powder is discharged, and after all the raw materials are discharged into the collection bunker, they are discharged into the material mixing machine, so as to obtain the required auxiliary materials for the liquid crystal glass. And it can improve the whole uniformity of the auxiliary materials, especially applied to liquid crystal glass batching production lines with higher requirements for the quality of the auxiliary materials.

The invention provides a production line for processing automobile leather, and belongs to the technical field of leather processing. The problem that the processing efficiency is low in the prior artis solved. The production line for processing the automobile leather comprises a base and a machine frame fixed to the base, one end of the machine frame is provided with a feeding frame, the other end of the machine frame is provided with a discharge frame, a first conveying roller and a plurality of second conveying rollers are rotationally arranged on the machine frame, one end of the first conveying roller is connected with a driving motor capable of enabling the first conveying roller to rotate, a first chain wheel is coaxially fixed to the other end of the first conveying roller, the second conveying rollers are arranged parallel to the first conveying roller, a second chain wheel is fixed to the ends of the second conveying rollers, a first chain is arranged between the first chainwheel and the second chain wheels in a sleeving mode, a spraying device capable of achieving spraying for the automobile leather is arranged above the second conveying rollers, a drying device capable of drying the automobile leather is arranged at the end close to the discharge frame, and the machine frame is further provided with a preparation mechanism capable of preparing coating liquid. Theproduction line has the advantage of improving processing efficiency.

The invention relates to the glass fiber impregnating compound preparation automatic control technical field, and specifically relates to a glass fiber impregnating compound preparation automatic control system comprising a controller; the controller is externally connected with an analog input output module; the input port of the analog input output module is externally connected with a viscositysensor, an oil temperature sensor, a water temperature sensor, a raw material flowmeter and a hot water flowmeter; the viscosity sensor is externally connected with a frequency meter; the input end of a controller switch value I/O module is externally connected with a water level upper limit detector, a water level lower limit detector, and a frequency transition annunciator; the output end of the controller switch value I/O module is externally connected with a raw material valve, an agitator motor, a steam valve, a hot water valve, a normal temperature water valve and a tap water valve. Thesystem can precisely control the key technique parameters, thus effectively preventing artificial operations from affecting the production stability, improving the impregnating compound preparation quality, reducing the worker laboring intensity, reducing operator quantity, reducing cost, and increasing gains.

The invention discloses an instrument and a method for rapidly preparing a medical medicament, which relate to the technical field of medical apparatuses and instruments, and solve the problems that an existing instrument is inconvenient to accurately convey various liquid medicines in the process of preparing the medical medicament, the preparation is inconvenient and the like. The instrument comprises a preparation mechanism, the inner side of the preparation mechanism is slidably connected with a stirring connection mechanism, and the stirring connection mechanism comprises a stirring frame, a sealing flow guide seat, a one-way flow guide transmission sleeve, a positioning sleeve, a transmission seat and a second supporting spring; a one-way flow guide transmission sleeve is slidably connected to the inner side of the sealing flow guide seat, a positioning sleeve is installed on the portion, located on one side of the sealing flow guide seat, of the outer side of one end of the one-way flow guide transmission sleeve, and a transmission seat is slidably connected to the outer side of the positioning sleeve. The preparation efficiency is effectively improved by using a stirring and sealed heating method, the preparation process can be conveniently controlled, and the quality of the prepared medicament is improved.

The invention provides a slow and controlled release coating tablet dissolution degree stability improving method. When the coating agent is of organic solvent, the optimal time for adding coating dry powder can be acquired by detecting the change of the emission concentration of organic solvent vapor of the exhausted gas of a coating machine with the time. The method is convenient to operate, the accuracy of the result is high, the preparation quality of slow and controlled release coating tablets can be improved effectively, and the stable solution degree is provided.