Preparation method of composite drug-eluting stent and its drug coated layer

A technology of eluting stents and drug coating, applied in the field of medical drug eluting stents, can solve controversial problems and achieve the effect of reducing economic burden
CN101007187AInactive Publication Date: 2007-08-01AFFILIATED HUSN HOSPITAL OF FUDAN UNIV +1
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Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
Publication Date
2007-08-01
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention discloses a making method of drug coating on the elution rack, which comprises the following steps: dissolving vitamin A acid drug and polymer in the organic solvent to obtain the coating liquid of vitamin A acid; coating the liquid on the predisposed metal rack surface; evaporating solvent; obtaining the buried vitamin A acid coating; dissolving estrogen drug and polymer in the organic solvent to obtain estrogen coating liquid; coating on the surface of estrogen coating liquid; evaporating; obtaining the product; or dissolving vitamin A acid, estrogen drug and polymer in the organic solvent to obtain the composition of drug and polymer; coating on the predisposed metal rack surface; evaporating; burying in the drug coating of vitamin A acid and estrogen.
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Description

[technical field]

[0001] The invention relates to the field of medical drug eluting stents, in particular to the drug coating on the eluting stents. [Background technique]

[0002] In recent years, with the improvement of living standards and changes in lifestyle, cardiovascular diseases represented by atherosclerosis have become the primary factor threatening life. For patients with moderate and moderate coronary heart disease, interventional therapy using percutaneous coronary angioplasty (PTCA) and stenting (stenting) has the advantages of small trauma, fast recovery, and wide application range, and is becoming the current coronary heart disease. Hotspots in heart disease treatment.

[0003] However, the occurrence of postoperative restenosis is the primary problem faced by interventional therapy. According to statistics, the incidence of restenosis after PTCA and stent implantation is 30-30% respectively after percutaneous coronary angioplasty (PTCA) and bare metal sten...

Claims

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