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Improved device for application of medicaments, manufacturing method therefor, and method of treatment

A dermatophyte disease, equipment technology, applied in the treatment of onychomycosis and athlete's foot, the process for producing the equipment, the field of equipment for treating human and animal skin pathogens, especially onychomycosis and athlete's foot, can solve the problems that are not involved or mentioned NO elution to regulate and/or control problems such as dermatological treatment to achieve an effective anti-corrosion effect

Inactive Publication Date: 2012-02-01
NOLABS AB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Regulation and / or control of NO elution and treatment of skin diseases are also not mentioned in this document
[0024] In addition, none of the above-mentioned documents refer to the further improvement of this technology in the treatment of diseases caused by dermatophytes, yeasts and molds, and the disease resistance of nitric oxide

Method used

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  • Improved device for application of medicaments, manufacturing method therefor, and method of treatment
  • Improved device for application of medicaments, manufacturing method therefor, and method of treatment
  • Improved device for application of medicaments, manufacturing method therefor, and method of treatment

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Embodiment Construction

[0036] The following description focuses on an embodiment of the invention as applied to a device in the form of a sheath / housing capable of achieving targeted treatment of infections caused by dermatophytes, yeasts and moulds, such as onychomycosis and athlete's foot. towards treatment.

[0037] For nitric oxide (nitric oxide NO), its physiological and pharmacological effects have attracted extensive attention and research. NO is synthesized from arginine by nitric oxide synthase (NOS). NOS is divided into constitutive enzyme (constitutive enzyme) cNOS and inducible enzyme (inducible enzyme) iNOS, the former exists in the living body in normal state, and the latter will be produced in large quantities in response to certain stimuli. We all know that compared with the depth of NO produced by cNOS, the concentration of NO produced by iNOS is 2 to 3 orders of magnitude higher, that is, iNOS will produce a very high amount of NO.

[0038] In the case where NO is produced in lar...

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PUM

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Abstract

A device is provided that allows for target treatment of infections, caused by dermatophytes, yeast fungus, and mould fungus, such as onychomycosis and dermatophytosis. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the infected area, such that a therapeutic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area.

Description

technical field [0001] The present invention relates generally to the treatment of tinea unguium, and in particular onychomycosis and athlete's foot. More particularly, the present invention also relates to a device for the treatment of human and animal skin pathogens, especially onychomycosis and athlete's foot, and a process for producing said device, using nitrogen oxide (NO) . Background technique [0002] Dermatophytes and yeasts are the most common skin fungal infections, but they are one of several conditions that can be acquired through direct skin-to-skin contact. They are mucilaginous and infect the skin, hair and nails. In some rare cases, molds may also be the source of infection (in most cases, infection with the following molds: Fusarium, Scytalidium, Hendersonula toruloidea, Brachypodium ( Scopulariopsis Brevicaulis), Aspargillus Nidulans, Acremonium, Exophalia, and Alterneria. Infections caused by dermatophytes are widespread throughout the world, but more...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/44A61L27/34A61L27/54A61L31/12A61L31/16C01B21/24A61K47/30A61P31/10
CPCA61L15/44A61L31/16A61L2300/114A61P31/10
Inventor 托尔·彼得斯
Owner NOLABS AB