Tumour target thermotherapy method based on metallic grain or its compound thermal chemical reaction
A technology of thermochemical reaction and metal particles, applied in medical science, heating surgical instruments, inorganic non-active ingredients, etc., can solve the problems of side effects of patients, high price, complex structure, etc., achieve reduced thermal damage, easy operation, and simplified instruments The effect of the design
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Embodiment 1
[0050] Metal nanoparticles or their compounds can be selected from pure solid particles or solid oxide particles and their combinations, for example, in a mixture composed of sodium and other metals, the content of sodium can be 1-99%; the ratio of other metals is the same as Same thing. By examining the properties of metals such as sodium, potassium, magnesium, and calcium, it is found that the heat of reaction between sodium and water is sufficient to meet the requirements of hyperthermia. At the same time, the sodium ions produced by the reaction are the main ions in the intracellular and extracellular fluids, which can participate in the metabolism of water and ensure the safety of the body. Water, acid and alkali balance; Potassium reacts with water to generate a lot of heat, while potassium ions help maintain nerve health, maintain a normal heartbeat, and assist in normal muscle contraction. These two metals are particularly suitable for tumor hyperthermia. The size of ...
Embodiment 2
[0070] The solid delivery method provided by the present invention can be in the form of a disposable injection. The simple one-time injection can directly adhere the liposome-encapsulated micro-nano solid particles to the end of the injection, and after the insertion position of the guide hole is determined, it will be sent in by the stent. Among them, the material of the bracket can be made of plastic or metal, and the hollow design guides the gas generated by the reaction to discharge the treatment area. The bracket can be designed in a cylindrical shape with a length of 10 mm to 300 mm and an inner diameter of 0.2 mm to 5 mm, and can be made of stainless steel or plastic.
Embodiment 3
[0072] The delivery method provided by the invention can directly inhale solid particles with a straw, and the injection port is encapsulated with paraffin.
[0073] When in use, the paraffin can be melted by heating, and the amount of release can be controlled by squeezing the air above the straw, so that the solid particles can be delivered to the targeted tumor area. The straw has a length of 10 mm to 300 mm and an inner diameter of 0.2 mm to 5 mm, and can be made of plastic.
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