Application of two bi-sesquiterpenes compound for preparing antineoplastic and antiinflammatory medicine

Abstract

The invention relates to an application of two sesquiterpenoids in preparing antitumor and anti-inflammatory medicines. The sesquiterpenoids are gochnatiolide A and gochnatiolide B, which can be extracted and separated from Ainsliaea fulvioides or other plants, or obtained by chemical synthesis. The experimental results show that the two sesquiterpenoids have good inhibitory effect on human tumorcells and have distinct inhibitory effect on inflammations. Therefore, the two sesquiterpenoids can be used for preparing antitumor and anti-inflammatory medicines.

Description

technical field The invention belongs to the technical field of medicine, and specifically relates to the application of two bisesquiterpene compounds, Zhongdian terpene A and Zhongdian terpene B, in the preparation of antitumor and anti-inflammatory drugs. Background technique Tumor is one of the main causes of human death. The Ministry of Health of China announced the main causes of death of urban and rural residents in 2006. Statistics show that malignant tumors have become the leading cause of death. It can be seen that the prevention and treatment of tumors is very urgent. Drug therapy is one of the main treatments for tumors. At present, although dozens of anti-tumor drugs have been developed, they can effectively prolong the life of patients or improve the quality of life of patients. Some of these anti-tumor drug treatments have very significant curative effects, such as drug treatment of acute leukemia in children. However, the research and development of tumor...

AI Technical Summary

Problems solved by technology

However, the research and development of tumor drugs still face great challenges. For example, most anti-tumor drugs are cytotoxic drugs, and their side effects are obvious, which limits the efficacy of these drugs.

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