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Medicinal composition for treating diabetes

A composition and diabetes technology, which can be used in drug combinations, metabolic diseases, pharmaceutical formulations, etc., and can solve problems such as intolerance to fatigue and poor curative effect.

Active Publication Date: 2012-07-04
北京中一堂科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Inquiring about the medical history, many vegetarians like to eat fat and sweet, fat or irritable or depressed, and often accompanied by epigastric fullness, dry mouth and bitter mouth, constipation, irritability or depression, intolerance to fatigue, red tongue coating when seeing a doctor Diarrhea, slippery and rapid pulse and other symptoms, the effect of taking Chinese patent medicines for nourishing qi and nourishing yin is often not obvious

Method used

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  • Medicinal composition for treating diabetes
  • Medicinal composition for treating diabetes
  • Medicinal composition for treating diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 tablet of the present invention

[0026] Bupleurum 30g, Paeoniae Alba 30g, Citrus aurantium 30g, Rhubarb 10g, Scutellaria baicalensis 30g

[0027] The 5 medicinal materials were extracted twice with 10 times their weight of water by reflux, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added 90% ethanol to 65% alcohol content, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 75°C to make dry paste powder.

[0028] Starch is added to make tablets.

Embodiment 2

[0029] The preparation of embodiment 2 capsules of the present invention

[0030] Bupleurum 30g, Paeoniae Alba 30g, Citrus aurantium 30g, Rhubarb 12g, Scutellaria baicalensis 30g

[0031] The 5 medicinal materials were extracted twice with 10 times their weight of water by reflux, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added absolute ethanol to 75% alcohol content, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 85°C to make dry paste powder.

[0032] Add lactose to make capsules.

Embodiment 3

[0033] The preparation of embodiment 3 concentrated pellets of the present invention

[0034] Bupleurum 27g, Paeoniae Alba 45g, Citrus aurantium 27g, Rhubarb 9g, Scutellaria baicalensis 27g

[0035] The 5 medicinal materials were extracted twice with 10 times their weight of water by reflux, each time for 1.5 hours. The extract was filtered, concentrated under reduced pressure to 1:1, added 95% ethanol to 70% alcohol content, filtered, concentrated under reduced pressure to form a thick paste. Vacuum drying at 80°C to make dry paste powder.

[0036] Add microcrystalline cellulose to make concentrated pellets.

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Abstract

The invention relates to a pharmaceutical compound used for treating diabetes, which is made of the following bulk drugs by weight portions: 3-15 portions of bupleurum, 3-15portions of white peony root, 3-15 portions of fruit of immature citron, 1-6 portions of Chinese rhubarb, and 1-6 portions of baikal skullcap; 3-15 portions of Chinese goldthread can be added or pinellia tuber, dark plum, trichosanthes root and berberine can be added. The compound is made by the following method: the bulk drugs are added with water for refluxing extraction to obtain an extract, the obtained extract is condensed and added with ethanol until the ethanol content reaches 65-75%, thus a mixture is obtained, the obtained mixture is filtrated to obtain a filtrate, vacuum concentration is carried out on the filtrate to obtain a thick paste, the obtained thick paste is dried into dry paste powder, and the dry paste powder is added with an adjuvant to obtain a pharmaceutically acceptable dosage form or is added with berberine and the adjuvant to obtain the pharmaceutically acceptable dosage form.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating diabetes and a preparation method thereof. Background technique [0002] Diabetes is a worldwide disease that seriously endangers human health. Diabetes mellitus is a chronic progressive lifelong disease caused by the disorder of sugar, protein and fat metabolism in the body, which is characterized by hyperglycemia and glucosuria. The disease can lead to heart and kidney complications, blindness and amputations. In recent years, it has been clinically observed that the incidence of diabetes is increasing year by year. At present, there are about 150 million diabetics in the world, and the number of diabetics in my country has exceeded 40 million. Among the diabetic cases, a few are insulin-dependent diabetes (type I), and most are non-insulin-dependent diabetes (type II). Most people with diabetes need life-long medication. Studies hav...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P3/10
Inventor 仝小林朱永宏周水平
Owner 北京中一堂科技有限公司