Injection for treating skin defects and preparation method thereof

A technology for skin defects and injections, applied in skin diseases, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of safety, slow effect, low collagen content, etc., to improve skin elasticity and luster, Enhance the thickness of the dermis and improve the effect of the skin matrix
CN101548988AInactive Publication Date: 2009-10-07北京赛尔泰和生物医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
北京赛尔泰和生物医药科技有限公司
Publication Date
2009-10-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to injection for treating skin defects which takes cells as main component, and the content of cell component in every milliliter of filler used for injection is 10-50 million; the cell component is of at least one type of dermal fibroblast stem cells, fibroblast precursor cells and fibroblasts which are obtained by collecting skin of aborted fetus and excised foreskin of newborn after in vitro culture and proliferation through low serum or serum-free. The invention also provides a preparation method of the injection for treating skin defects. The invention has the advantages of immediate and obvious filling and repairing effects after injection, lasting curative effect, and simple and convenient treating procedures.
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Description

technical field

[0001] The invention relates to a tissue filler and a preparation method thereof, more specifically, an injection for treating skin defects and a preparation method thereof. Background technique

[0002] Human soft tissue augmentation is the main treatment method for repairing soft tissue after injury. In the nineteenth century, paraffin and silicone were used for filling. After the 1980s, gelatin powder materials appeared again, but they all had problems such as uncertain curative effect and large toxic and side effects.

[0003] After 1997, Isolagen used autologous fibroblasts as mass tissue filling materials, which had a certain curative effect, but there were problems such as slow effect and insignificant curative effect.

[0004] Chinese patent 03155833.X discloses an injection for removing wrinkles and scars. It uses autologous skin, which is isolated, cultured and amplified in vitro, and is made into an injection in glucose solution to treat scars an...

Claims

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