57results about How to "Repair effect" patented technology

The present invention relates to a composition for maintenance of bone health or prevention, alleviation and / or treatment of bone disorders. It also relates to the use of the composition in the manufacture of a nutritional product, a supplement, a treat or a medicament; and a method of promoting bone growth or for the maintenance of bone health, which comprises administering an effective amount of the composition.

A method of cosmetically repairing a skin contour irregularity in a subject is provided. The method is effected by introducing cartilage producing cells into the skin contour irregularity thereby effecting cosmetic repair thereof. A medical implant coated with cartilage producing cells is further disclosed.

Three novel low molecular weight (LMW) polypeptide fragments of a proteolipid protein human PLP / DM20 are designated PIRP-M, PIRP-L and PIRP-J, and are growth factors for oligodendrocytes with anti-apoptotic activity. They are encoded by mRNA from an IRES. Fusion polypeptides of such a LMW polypeptide, DNA encoding the LMW polypeptide and fusion polypeptide, expression vectors comprising such DNA, and cells expressing such polypeptides, or pharmaceutical compositions thereof, are useful for stimulating neural stem cell differentiation, maturation along the oligodendrocytic pathway and proliferation of oligodendrocytes or precursors. These compositions can protect oligodendrocytes (and nonneural cells) from apoptotic death. Thus, the present composition is used to treat a disease or condition in which such differentiation, maturation and proliferation or inhibition of cell death, including remyelination or stimulation of oligodendroglia or Schwann cells, is desirable. Disorders include multiple sclerosis, trauma with Parkinson's-like symptoms, hypoxic ischerriia and spinal cord trauma.

A cushioning mechanism for a treadmill having a pair of ⊃-shaped rigid connection elements and a pair of pivotal rigid cushioning elements that are interposed between the bottom surface of both sides of the platform frame and the base bars. The pivotal rigid cushioning element includes a guidewheel at one end thereof. In this way, the guidewheel is movable on the surface of the base bar when the platform frame is moved up and down by the external forces applied to it. Accordingly, the cushioning and restoring effects can be achieved. Moreover, a resistance-adjusting element is provided at the bottom of the guidewheel. A free adjustment of the cushioning force may be achieved by the inclination of the resistance-adjusting element.

A cushioning mechanism for a treadmill having a pair of ⊃-shaped rigid connection elements and a pair of pivotal rigid cushioning elements that are interposed between the bottom surface of both sides of the platform frame and the base bars. The pivotal rigid cushioning element includes a guidewheel at one end thereof. In this way, the guidewheel is movable on the surface of the base bar when the platform frame is moved up and down by the external forces applied to it. Accordingly, the cushioning and restoring effects can be achieved. Moreover, an auxiliary supporting element is pivotally interposed between both sides of the platform frame and the handle frame assembly, respectively. As a result, a complete cushioning and restoring effect can be ensured.

Three novel low molecular weight (LMW) polypeptide fragments of a proteolipid protein human PLP / DM20 are designated PIRP-M, PIRP-L and PIRP-J, and are growth factors for oligodendrocytes with anti-apoptotic activity. They are encoded by mRNA from an IRES. Fusion polypeptides of such a LMW polypeptide, DNA encoding the LMW polypeptide and fusion polypeptide, expression vectors comprising such DNA, and cells expressing such polypeptides, or pharmaceutical compositions thereof, are useful for stimulating neural stem cell differentiation, maturation along the oligodendrocytic pathway and proliferation of oligodendrocytes or precursors. These compositions can protect oligodendrocytes (and nonneural cells) from apoptotic death. Thus, the present composition is used to treat a disease or condition in which such differentiation, maturation and proliferation or inhibition of cell death, including remyelination or stimulation of oligodendroglia or Schwann cells, is desirable. Disorders include multiple sclerosis, trauma with Parkinson's-like symptoms, hypoxic ischerriia and spinal cord trauma.

The present invention relates to methods for treating multiple sclerosis by combining immunotherapy with myelin repair.

The invention relates to a braking control system for automotive vehicles comprising a braking control member (1), a brake booster (4) and a brake master cylinder (5). The system of the invention further comprises a simulator (3) coupled pneumatically to the piston (42) of the brake booster (4). Said simulator (3) receives at least one braking command from the braking control member (1) and makes it possible to establish, in return, a difference in pressure between the front chamber (40) and the rear chamber (41) of the brake booster so as to control the displacement of the piston (42).

Methods for treating diseased or damaged tissue in a subject are disclosed, involving administering to said subject at a site wherein diseased or damaged tissue occurs, cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and / or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and / or gel-forming substance. Where the cells and / or suitable progenitor cells thereof are chondrocytes, embryonic stem cells and / or bone marrow stromal cells, the methods of the invention are suitable for treating, for example, articular cartilage degeneration associated with primary osteoarthritis. Also disclosed is a device having tissue-like characteristics for treating diseased or damaged tissue in a subject, wherein the device comprises cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and / or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and / or gel-forming substance.

The invention is a unit for fixing an antenna, comprising: a base element suited to support the antenna, provided with a contact surface suited to rest against a plate-like supporting body; a fixing element comprising a main body suited to be connected to the base element through joining means that define a connection direction, and a projecting body mainly developed according to the connection direction and associated with the main body through a deformable connection section. The projecting body has a reference surface facing a corresponding thrust surface of the main body and spaced from it, the connection section being configured so that its deformation makes it possible to move near each other and bring into contact the reference surface and the thrust surface when the fixing element is connected to the base element.

Transmissivity is restored to a gallium stained substrate by directing an electron beam to the substrate in the presence of an etching gas. For higher concentrations of implanted gallium, the transparency can be substantially restored without reducing the thickness of the substrate. For lower doses of implanted gallium, the transmission is restored to 100%, although the thickness of the substrate is reduced. The invention is suitable for use in the repair of photolithography masks.

The invention relates to an injection for treating skin defect, which mainly comprises cell component and platelet-rich blood plasma, the content of the cell component in per milliliter of the injectable filler is ten million to fifty million, and the content of platelets is 100 to 700 multiplied by 106; and the cell component is at least one of dermal fibrotic stem cell, fibrotic precursor cell and fibroblast which are obtained by culturing and expanding aborted foetus kin or circumcised neonatal foreskin in vitro in low or no serum. The platelets are extracted from the autoblood of a treated patient as well. The invention also provides a preparation method for the injectable soft tissue filler. The invention has the following advantages that: after injection, notable filling and repairing effects can be shown at once, moreover, the curative effect is persistent, the treatment procedure is simple.

A computer assembly for example for use as a network server comprises housing a host processor located within the housing and, a service processor also located within the housing for providing system management functions within the computer assembly. The housing includes a display that is located thereon for displaying the status of components of the assembly obtained from the service processor, and one or more manual switches located on the housing for enabling a user to vary information displayed by the display and / or to alter the status of the equipment. The computer assembly may include a console interface that communicates with the service processor to enable the system management functions of the assembly to be monitored and / or the status thereof to be modified from a remote console connected thereto in addition to or instead of by the display and switches.

An artificial hair restorer has a trunk hair with plural restoring hairs fixed to certain points of the trunk hair. A loop formed by folding one or two trunk hair(s) in two, and the original hair(s) passes(pass) through the loop. A knot is provided close to the tying end of the restoring hairs but opposite to the loop. A hair restoring method comprises inserting one or more original hair(s) into the loop of the trunk hair, and then fixing the trunk hair to a point in the vicinity of the original hair root.

The invention relates to a braking control system for automotive vehicles comprising a braking control member (1), a brake booster (4) and a brake master cylinder (5). The system of the invention further comprises a simulator (3) coupled pneumatically to the piston (42) of the brake booster (4). Said simulator (3) receives at least one braking command from the braking control member (1) and makes it possible to establish, in return, a difference in pressure between the front chamber (40) and the rear chamber (41) of the brake booster so as to control the displacement of the piston (42).Application: Brakes for automotive vehicles.

The invention discloses a compound fertilizer for remediation of organic contaminated sandy saline-alkali soil. The compound fertilizer comprises an organic fertilizer, a compound water-retaining agent, a sandy saline-alkali soil remediation agent and an organic contaminated soil remediation agent in a weight ratio of (29-33):(10-14):(15-19):(38-42). The invention also discloses a preparation method of the compound fertilizer. The compound fertilizer provided by the invention can effectively improve the structure of the sandy saline-alkali soil, reduce the salinity and alkalinity, improve a nutrient content of the soil, reduce a content of organic pollutants in the soil and effectively remediate the saline-alkali soil for a long time.

A significant change in the static angular position can be produced from a small physical displacement of the flexible member. The flexible member 12 in a magnetic head unit 95 is stressed for adjusting the static angular position. Simultaneously, the stressed areas 14 are irradiated by a laser beam LA.

The invention discloses a repairing agent for a skin defect and a preparation method thereof. Each milliliter liquid of the repairing agent for the skin defect contains 10-50 million cells; the cells are dermal fibroblastic stem cells, fibroblastic precursor cells and fibroblasts which are collected after the cut neonatal preputial skin is subjected to in-vitro low serum primary culture and passage amplification; and the liquid is prepared by mixing amino acid injection with 5% of glucose injection at a volume ratio of 1:0.5-2. The repairing agent provided by the invention has the following advantages that the repairing agent for the skin defect has more cell viability and amplification; the combined action without rejection is achieved on the external applied parts and skin tissues; the obvious filling and repairing effects are achieved after the repairing agent is externally applied for one week; and the curative effect is lasting and the treatment schedule is simple and convenient.

Fast-acting oral formulations with restored entourage effects are described. The formulations include beneficial combinations of plant-derived molecules to provide restored entourage effects, and one or more carriers. The carriers can include N-acylated fatty amino acids, absorption enhancers, and / or various other beneficial carriers. The fast-acting oral formulations can create administration benefits.

The invention relates to a Chinese medicinal composition for treating rhinitis, and a preparation method thereof and a Chinese medicinal preparation. The Chinese medicinal composition comprise 15-25 parts of fructus Xanthii, 15 to 25 portion of radix Saposhnikoviae, 12 to 20 part of schizonepeta, 12 to 20 part of chuanxiong rhizome, 12 to 20 part of angelica dahurica, 12 to 20 part of asarum, 15 to 25 part of magnolia flower, 15 to 30 part of centipede herb, 15-25 part of mint, 15-22 parts of kaempferol and 18-30 part of dandelion, wherein that raw materials are respectively weighed accordingto the weight ratio of the fructus Xanthii, radix Saposhnikoviae, herba Schizonepetae, rhizoma Ligustici Chuanxiong, radix Angelicae Dahuricae, herba asari, flos Magnoliae, herba Centipedae, herba Menthae, kaempferi and dandelion, respectively crushed and ground into 200-mesh powder, and each raw material powder is mixed uniformly, sterilized and packaged. A Chinese medicine in that form of powderfor fumigating nasal cavity is prepare from Chinese-medicinal composition and features quick effect, short course of treatment, high cure rate, curative effect on both symptoms and root cause, and norecurrence after cure. The Chinese medicinal composition has small irritation, uniform effect, easy to absorb the drug ingredients, avoiding the blurring of the target and other adverse reactions when systemic drug use.

A method of cosmetically repairing a skin contour irregularity in a subject is provided. The method is effected by introducing cartilage producing cells into the skin contour irregularity thereby effecting cosmetic repair thereof. A medical implant coated with cartilage producing cells is further disclosed.

In some embodiments, a composition for the treatment and inhibition or prevention of arthritic diseases includes an extract of mixed herbs, the mixed herbs including an active ingredient with Lonicera japonica THUNB and Anemarrhena asphodeloides BUNGE.

The present invention relates to a composition for maintenance of bone health or prevention, alleviation and / or treatment of bone disorders. It also relates to the use of the composition in the manufacture of a nutritional product, a supplement, a treat or a medicament; and a method of promoting bone growth or for the maintenance of bone health, which comprises administering an effective amount of the composition.

The invention provides a coupling member for use in the repair of pipes and pipelines of from 90 mm to 250 mm in diameter, such as those used for the pipeline transportation and delivery of domestic and industrial liquids such as water, gas, oil and other petrochemicals. Two coupling members are used for each repair. Each has a first collar portion for surrounding the new pipe section and a second collar portion for surrounding a cut end portion of the old pipe section, and the two pipe connectors are located with their respective first collar portions adjacent to one another and their respective second collar portions facing mutually outwardly towards the opposite ends of the new pipe section. Pressure chambers are formed between the annular grooves and the seal members of the first collar portions and between the annular grooves and the nitrile rubber sealing rings of the second collar portions.

The invention relates to injection for treating skin defects which takes cells as main component, and the content of cell component in every milliliter of filler used for injection is 10-50 million; the cell component is of at least one type of dermal fibroblast stem cells, fibroblast precursor cells and fibroblasts which are obtained by collecting skin of aborted fetus and excised foreskin of newborn after in vitro culture and proliferation through low serum or serum-free. The invention also provides a preparation method of the injection for treating skin defects. The invention has the advantages of immediate and obvious filling and repairing effects after injection, lasting curative effect, and simple and convenient treating procedures.

A computer assembly for example for use as a network server comprises housing a host processor located within the housing and, a service processor also located within the housing for providing system management functions within the computer assembly. The housing includes a display that is located thereon for displaying the status of components of the assembly obtained from the service processor, and one or more manual switches located on the housing for enabling a user to vary information displayed by the display and / or to alter the status of the equipment. The computer assembly may include a console interface that communicates with the service processor to enable the system management functions of the assembly to be monitored and / or the status thereof to be modified from a remote console connected thereto in addition to or instead of by the display and switches.

The invention discloses a soil water-retaining agent produced from aluminum ash and a preparation method thereof. The method comprises the following steps: respectively adding dilute nitric acid and asodium sulfide solution into the aluminum ash to remove heavy metals in the aluminum ash until the content reaches an agricultural heavy metal limit standard; mixing the aluminum ash without the heavy metals with a calcium-based compound, and grinding; activating the fully mixed materials at a high temperature to obtain a material taking calcium sulphoaluminate as a main mineral component; and finally, under the hydration condition, obtaining the soil water-retaining agent which takes ettringite with 32 crystal water as a main mineral component and has a weak base characteristic. The productcan be applied to drought resistance and improvement repair work of soil in arid and semi-arid regions. According to the method, efficient agricultural comprehensive utilization of the aluminum ash which is an aluminum extraction secondary byproduct is realized, and a scientific method is provided for reducing aluminum ash stockpiling and fully utilizing aluminum resources; the prepared ettringitewater-retaining agent has a certain soil water-retaining capacity and a good long-term water-retaining effect, and the production cost of the product is low.

The extract of Siegesbeckiae herba of the present invention showed potent inhibitory effect on the dissociation of proteoglycan and type II collagen in chondrocyte and cartilage tissue and protecting effect on cartilage due to the inhibition of MMP-1, MMP-3 and MMP-13 activity and the restoring effect on cartilage tissue, the anti-inflammatory and antiphlogistic effect in edema animal model, anti-inflammatory effect confirmed by the inhibition test on PGE2 activity through COX-2 inhibition and the inhibition test of the reproduction of TNF-α and NO, it can be used as the therapeutics or health food for treating and preventing arthritic disease.