Medicine composition for healing wounds and preparation method thereof

A pharmaceutical composition and wound healing technology, applied in the field of pharmaceutical composition and its preparation that can heal chronic wounds and general burn wounds, can solve problems such as inability to provide healing products, poor circulation of peripheral blood vessels, and inability to self-heal wounds, etc. Achieve the effects of increasing fibroblast proliferation, easy acquisition and quality control of medicinal materials, and promoting wound healing

Inactive Publication Date: 2009-11-25
毛玉麟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For diabetic patients who cannot heal their wounds due to poor peripheral blood circulation, it does not provide a good healing product
[0006] In addition, Centella asiatica has been used in burns and other wound healing, and there are many studies on fibroblasts, and its use has a long history, but there is no research on the application of centella asiatica to chronic wounds such as diabetes and bedsores. wound healing

Method used

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  • Medicine composition for healing wounds and preparation method thereof
  • Medicine composition for healing wounds and preparation method thereof
  • Medicine composition for healing wounds and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Take 500 grams (g) of dried Centella asiatica whole grass, preferably in powder form, put it in a 5 liter (L) container, and add 4 to 10 times the volume of the mixed substance and ethanol with a weight percentage of 20% to 80% , and preferably 2800 milliliters (ml) of 50% ethanol as the extraction solvent to obtain an extraction solution, the extraction solution was heated at 50 to 70°C for 3 to 10 hours, then cooled and then filtered to obtain the extraction filtrate . Next, concentrate the filtrate under reduced pressure until it becomes a paste, and use spray drying or freeze drying, or add an excipient with a weight percentage of 5% to 80% to dry the filtrate into a solid state, and then pulverize it to obtain a powder Centella asiatica extract.

Embodiment 2

[0034] Take 500 grams of medicinal roots of Scutellaria baicalensis, preferably in powder form, and also in the form of raw medicinal materials or slices, put it in a 5-liter container, and add 4 to 10 times the volume of the material and the weight percentage is 20%~ 90% ethanol, preferably 2800 liters of 50% ethanol as the extraction solvent to obtain the extraction solution, after heating the extraction solution at 50-70°C for 3-10 hours, cooling and then filtering to obtain the extraction filtrate . Next, concentrate the filtrate under reduced pressure until it becomes a paste, and use spray drying or freeze drying, or add excipients with a weight percentage of 5% to 80% to dry the filtrate into a solid state, and then crush it to obtain powdered Scutellaria baicalensis Extracts.

Embodiment 3

[0036] Take 500 grams of Centella asiatica whole herb, preferably in powder form; 500 grams of medicinal root parts of Scutellaria baicalensis, preferably in powder form, the weight ratio of Centella asiatica whole herb and the medicinal root parts of Scutellaria baicalensis is 1 Compared with one, the two are placed together in a container of 5 liters, and adding 4 to 10 times the volume of the material and 20% to 90% ethanol by weight, preferably 2800 liters of 50% ethanol as the extraction solvent, to obtain an extraction solution, heating the extraction solution at 50-70° C. for 3-10 hours, cooling and then filtering to obtain an extraction filtrate. Next, concentrate the filtrate under reduced pressure until it becomes a paste, use spray drying or freeze drying, or add excipients with a weight percentage of 5% to 80% to dry the filtrate into a solid state, and then crush it to obtain powdered snow Herbal extract plus Scutellaria baicalensis extract. In addition, there is...

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PUM

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Abstract

The invention discloses a medicine composition for healing wounds and a preparation method thereof. The medicine composition for healing wounds can be applied to the fields of diabetes mellitus, bedsore, wound, burn and scald, acne, whelk, operated skin repair and healing, cosmetic skin repair, and the like. The composition comprises 0.01-6 of scutellaria extraction, 0.1-25 of herba cntellae extraction and the balanced of additive according to the weight percent. The preparation method is realized by the following steps: extracting the herba cntellae extraction and the scutellaria extraction from a whole herba cntellae and the root of scutellaria, and then preparing the two extractions into the medicine composition. The medicine composition is used for healing chronic wounds and burn and scald wounds, can obviously enhance the hyperplasia of fiberblast when the chronic wounds heal, achieves the effect of healing wounds and can not roll skin or cause granuloma in the healing process.

Description

technical field [0001] The invention relates to a wound-healing medicinal composition and a preparation method thereof, in particular to a medicinal composition capable of healing chronic wounds and common burn wounds and a preparation method thereof. Background technique [0002] With the aging of the world's population structure and the advancement of medical science, the life expectancy of human beings has also been extended. Coupled with the improvement of quality of life, human nutrition has become increasingly refined, and the population of diabetes has also increased rapidly. But the aging society is relatively senile diseases. [0003] According to statistics from Taiwan, the incidence of diabetes is about 3.6%, and there are about 150 million people in the world suffering from diabetes. Diabetics have a 12-15% risk of developing foot ulcers throughout their lifetime. The market for wound healing products is estimated to be approximately US$6.4 billion by 2009. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61P17/02A61P17/10A61P17/16A61L27/60A61K33/18A61K31/63
Inventor 毛玉麟
Owner 毛玉麟
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