PET concentration reestablishing method based on Kalman filtration in limited sampling angle

A technology of Kalman filtering and sampling angle, applied in echo tomography, computerized tomography scanner, etc., can solve problems such as untargeted solutions

Active Publication Date: 2010-01-20
ZHEJIANG UNIV
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Problems solved by technology

Although there is a small amount of research on the reconstruction problem under limited sampling angles in computed tomography (CT), there is currently no specific solution to this problem in the field of PET imaging.

Method used

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  • PET concentration reestablishing method based on Kalman filtration in limited sampling angle
  • PET concentration reestablishing method based on Kalman filtration in limited sampling angle
  • PET concentration reestablishing method based on Kalman filtration in limited sampling angle

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Embodiment Construction

[0052] The positron emission tomography scanner detects the photon signals emitted in the human body, and after the coincidence judgment and acquisition system processing, the projection lines are formed and stored in the computer hard disk in the form of sinograms. The computer takes the sinogram as input, invokes the image reconstruction module, and calculates the image of drug radioactive concentration distribution in the human body.

[0053] The specific implementation steps of the inventive method are as follows:

[0054] 1. When using a PET positron emission tomography scanner, a transmission scan and an emission scan are performed. The attenuation correction factor for the image is obtained from the transmission scan.

[0055] In the simulation test, because it can be compared with the original image, only a range is selected for the limited sampling angle, that is, 30°<θ<150°. In the real experiment, due to the lack of comparison with the original image, in order to ...

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Abstract

The invention discloses a PET concentration reestablishing method based on Kalman filtration in a limited sampling angle, comprising the following steps: obtaining incomplete sine figure data of an original projection line by a PET positive electron emission faultage scanner; establishing a state space system by combining a house model theory; and finally solving by a Kalman filtering method based on the state space theory to obtain radioactivity distribution, namely realizing image reestablishment. Because of the transcendental guide of a house model and the high adaptability of the Kalman filtering method on the incomplete data, the quality of a reestablished PET image is not influenced by data loss. Compared with an MLEM experiment of the prior reestablishing method, both the qualitative analyzing result and the quantitative analyzing result indicate that the method has certain superiority.

Description

technical field [0001] The invention relates to a positron emission tomography image reconstruction method, in particular to a Kalman filter image reconstruction method in PET imaging under the condition of limited sampling angle. Background technique [0002] Positron emission tomography (PET) is one of the most important applications of nuclear medicine imaging devices, and has become an important means of in vivo functional imaging. The basic idea of ​​PET is: inject isotope-labeled compounds into the organism, the isotope is unstable, emits positrons through decay and annihilates with electrons in the human body, emits a pair of photons with almost opposite directions, and obtains drugs by detecting the pair of photons in vitro The radioactivity concentration distribution. Nowadays, PET images have been widely used in many fields of clinical medicine for the diagnosis of tumors, heart diseases, nervous and psychiatric diseases, and they are also playing an increasingly ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/03
Inventor 沈云霞刘华锋
Owner ZHEJIANG UNIV
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