Inducing tool of animal myopia model

Abstract

The invention relates to a tool for carrying out form sense deprivation on an animal to induce myopia in myopic eye research. An inducing tool of an animal myopia model is an eyeshade which is rectangular approximately; the eyeshade is made of a plastic board which is non-toxic and has certain plasticity; the upper edge of the eyeshade deflects forwards to a position corresponding to the nasal side of the animal; the upper edge of the eyeshade extends backwards to a position corresponding to the back part of an auricle of the animal; and a first notch is arranged at the position correspondingto the auricle of the animal, and the position, corresponding to an eyeball of the animal, is provided with an opaque hemisphere which is carinal outwards. Compared with the prior art, when being adopted to carry out myopia induction test on the animal, the inducing tool has the advantages of little pain born by the animal, convenience, stability, duration, light wound, high efficiency and low cost.

Description

technical field [0001] The invention relates to a tool for inducing myopia by performing form deprivation on animals in myopia research. Background technique [0002] In myopia research, in order to understand the mechanism of myopia, animal models are generally used as experiments, and chickens, tree rats, monkeys, guinea pigs, etc. are generally used as models. At present, mice have become a good model organism for myopia-related research that is widely used at home and abroad. Compared with other model organisms for myopia-related research, mice have unique advantages. The current method of inducing myopia in mice is mainly "form deprivation". [0003] At present, there are mainly four methods of mouse form deprivation commonly used at home and abroad: [0004] 1. Eyelid suturing was pioneered by Spaniards Jaime Tejedor and Pedro de la Villa, and was adopted by Sun Yat-sen University and Fudan University in China. [0005] 2. Head-mounted goggles method (head frame + ...

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Problems solved by technology

[0005] 2. The Head-mounted goggles method (head frame + blindfold method) was pioneered by Americans Amanda E.Faulkner, Moon K.Kim, etc., and no one in China has adopted this method

[0032] Main disadvantage: easy to fall off, needs to be closely observed, observe the covering situation three times a day, once found to fall off, immediately re-stick or suture

[0043] The above four methods all have great disadvantages. At present, there is no ideal animal form deprivation tool at home and abroad, and it is urgent to develop a new ideal tool that is safe, convenient, stable, durable, lightly invasive, efficient, and low-cost. animal form deprivation tool

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