The invention relates to medical apparatus, especially relates to a multi-functional automatic moderation device for transfusion, comprising 
medicine preparation device, air exhauster and air passage conversion device; and said 
medicine preparation device comprises medical agent 
bottle, transfusion 
bottle, air conduit and long needle head. The two ends of liquid conduit are connected with needle head, and they are inserted into medical agent 
bottle and transfusion bottle to form liquid circuit. The air exhauster comprises 
air pump and air conduit, and the air passage conversion device is equipped with air conversion valve, valve core automatic driving device. The air passage conversion is also provided with air vent interface A, B, C, D, A is connected to air, C is connected with air exhauster, B and D are connected to medical agent bottle and transfusion bottle of 
medicine preparation device through air conduit and short needle head, respectively. When control valve core is connected with B, C, A and D, the liquid is transported to medical agent bottle from transfusion bottle, and when valve core is connected to A and B, C and D, the liquid refluxes from medical agent bottle to transfusion bottle. The invention is characterized buy simple operation, high efficient medicine preparation and no 
pollution.