Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Copper cluster two-photon absorbing material with living cell developing function and synthetic method thereof

A technology of two-photon absorption and cell imaging, which is applied in the direction of luminescent materials, copper organic compounds, chemical instruments and methods, and can solve the problems of not obtaining multi-branch monovalent copper clusters and large steric hindrance of pyridine ligands. , to achieve the effect of high yield, low cost and long wavelength

Inactive Publication Date: 2010-07-28
ANHUI UNIVERSITY
View PDF3 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the large steric hindrance of pyridine ligands with D-π-A conjugated structures, no multi-branched monovalent copper clusters with large π-conjugated systems have been obtained so far.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Copper cluster two-photon absorbing material with living cell developing function and synthetic method thereof
  • Copper cluster two-photon absorbing material with living cell developing function and synthetic method thereof
  • Copper cluster two-photon absorbing material with living cell developing function and synthetic method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0020] Now take R-CHO as 4-N, N-diethylaminobenzaldehyde is an example, and the non-limiting examples are described as follows:

[0021] 1. Preparation of pyridine ligands with D-π-A conjugated structure:

[0022] The synthetic route map is as follows:

[0023]

[0024] In the 50mL round bottom flask, add 11.3mL tert-butanol, 0.78g metal potassium, after the reaction is complete, add 1.77g 4-N, N-diethylaminobenzaldehyde (R 1 ), 0.975mL of 4-picoline, heated and stirred at 80°C for 2h, evaporated tert-butanol under reduced pressure, added 200mL of dichloromethane to the reaction solution, then poured the reaction solution into 200mL of ice-water mixture, stirred, and removed the lower layer of organic phase, the upper aqueous phase was extracted three times with 50mL dichloromethane respectively, the organic phases were combined, and poured into anhydrous Na 2 SO 4 , dried overnight, and distilled off dichloromethane to obtain a crude product, which was recrystallized fr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a copper cluster two-photon absorbing material with a living cell developing function, which is a univalent copper cluster with a multi-branched general chemical formula. The copper cluster two-photon absorbing material is prepared by the steps of: firstly, preparing a pyridine ligand from 4-methylpyridine and 4-N,N-2R-aminobenzaldehyde; and secondly, synthesizing a target product by using the pyridine ligand and cuprous iodide.

Description

1. Technical field [0001] The invention relates to a two-photon absorbing material and a preparation method thereof, in particular to a copper cluster compound two-photon absorbing material with low toxicity and a living tissue cell developing function and a synthesis method thereof. 2. Background technology [0002] In recent years, with the discovery of two-photon absorbing materials, two-photon fluorescence technology has made a major breakthrough in its application. Since the two-photon technology uses long-wavelength excitation (near-infrared), it has the characteristics of low excitation energy, long wavelength, strong penetration, and small photodamage. It has attractive application prospects in medical diagnosis and fluorescence microscopy imaging. In 2004, O'Halloran (J.Am.Chem.Soc., 2004, 126, 712-713) reported the use of Zn(II) ion-centered complex two-photon fluorescence microscopy in the detection of living tissue cells The application of this method has succes...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07F1/08C07F19/00C07F17/02C09K11/06
Inventor 田玉鹏汪徐春吴杰颖张胜义金葆康周虹屏杨家祥
Owner ANHUI UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com