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Polyethylene glycol-electrolyte oral solution

A polyethylene glycol and oral solution technology, which is applied in the direction of digestive system, metabolic diseases, inorganic active ingredients, etc., can solve problems such as inability to ensure isotonicity inside and outside the intestinal tract, inability to guarantee solution osmotic pressure ratio, and deviation of solution concentration, etc. , achieve quick effect, good cleaning effect and controllable quality

Active Publication Date: 2010-08-18
BEIJING SHENGYONG PHARMA
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Problems solved by technology

The problem is that there is a loss of components when preparing the solution, resulting in uneven proportioning of the components; or because there is no accurate metering container, and the user's own problems deliberately increase or decrease the amount of water added, so that the solution of the final product There is a deviation in the concentration, and the osmotic pressure ratio of the solution cannot be guaranteed to be 1, and the isotonicity inside and outside the intestinal tract cannot be guaranteed, which not only affects the cleaning effect, but also may cause serious adverse reactions
At present, there are only a few hospitals in China that use "powder" for intestinal cleansing, and there are only a few who have the conditions to strictly control the preparation of drug solutions. Serious consequences of improper preparation

Method used

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  • Polyethylene glycol-electrolyte oral solution
  • Polyethylene glycol-electrolyte oral solution
  • Polyethylene glycol-electrolyte oral solution

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Abstract

The invention provides polyethylene glycol-electrolyte oral solution, which comprises 59 to 60 grams of polyethylene glycol, 1.0 to 1.5 grams of sodium chloride, 0.5 to 1.0 gram of potassium chloride, 1.5 to 2.0 grams of sodium bicarbonate, 5.5 to 6.0 grams of sodium sulfate, 0.02 to 0.5 gram of edentate, 0.02 to0.5 gram of sweetener, 1 to 2 milliliters of flavoring essence and the balance of deionized water, wherein the solution is 1,000 milliliters. The polyethylene glycol-electrolyte oral solution is used in bowel cleansing and has the characteristics of quick response, safety, reliability and good cleansing effect. The oral solution is mainly suitable for cleansing bowels before colonoscopy, barium enema X-ray examination and gastrointestinal operation. The small-dose (about one eighth of a bowel cleansing dose) products of the oral solution can be used for treating chronic constipation.

Description

This application is a divisional application of Chinese patent application 200610056712.0. Original application date: 2006-3-6 Original application number: 200610056712.0 Invention-creation name of the original application: polyethylene glycol-electrolyte oral solution technical field The invention relates to a polyethylene glycol-electrolyte oral solution, which belongs to the field of pharmaceutical preparations. Background technique With the continuous improvement of people's living standards, the number of intestinal cancer and various intestinal diseases increases, and the number of intestinal operations and colonoscopy examinations is increasing day by day. According to preliminary investigations, only about 40,000 to 50,000 patients with colonic diseases in large hospitals in Beijing, Shanghai, and Tianjin need medical treatment, examination and treatment every year, while intestinal cleansing and pretreatment methods basically stay in foreign countries in the...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/08A61P3/12A61P1/10A61K31/197A61K31/765A61K33/04A61K33/00
Inventor 陶忠华张红妹刘静朱莉亚
Owner BEIJING SHENGYONG PHARMA
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