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Disinfectant

A technology of disinfectant and weight percentage, which is applied in the direction of medical preparations with non-active ingredients, active ingredients of iodine compounds, skin diseases, etc., which can solve the problems of human or animal injuries, inability to disinfect mucous membranes and wounds, and inappropriate consumption of iodine resources And other issues

Inactive Publication Date: 2010-10-20
吴岗
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the other hand, it is highly corrosive and irritating. It can only be used for skin disinfection, not for mucous membrane and wound disinfection. If it is not handled properly, it will cause harm to human or animal bodies.
For a long time, people have not been able to handle the duality of iodine to an optimal state, that is, to maximize the bactericidal efficacy and safety
And the available iodine content of general iodine is all more than 2%, and this is very inappropriate for the consumption of iodine resource that is more and more in short supply

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] 1) Iodine 0.1%:

[0013] 2) 0.4% polyvinylpyrrolidone;

[0014] 3) Potassium iodide: 0.03%;

[0015] 4) Sodium dodecylbenzenesulfonate 0.02%;

[0016] 5) Purified water 99.45%.

[0017] After the above components were mixed, they were fully stirred to make a medicinal solution. In a laboratory test, the effect was 7 minutes, and the killing rate to Escherichia coli was 99.94; the killing rate to Candida albicans was 99.99; the killing rate to Staphylococcus aureus The rate is 99.95; the action time is 1 minute, and the rate of killing natural bacteria on the surface of the opponent's skin is 99.76. Its bactericidal effect is better than 2% iodine, and no discomfort was found when applied to the skin, mucous membranes and wounds.

Embodiment 2

[0019] 1) Iodine 0.5%;

[0020] 2) Polyvinylpyrrolidone 2.0%;

[0021] 3) Potassium iodide: 0.15%;

[0022] 4) Sodium dodecylbenzenesulfonate 0.1%;

[0023] 5) Purified water 97.25%.

[0024] After the above components were mixed, they were fully stirred to make a medicinal solution. In a laboratory test, the effect was 7 minutes, and the killing rate to Escherichia coli was 99.93; the killing rate to Candida albicans was 99.95; the killing rate to Staphylococcus aureus The rate is 99.97; the action time is 1 minute, and the rate of killing natural bacteria on the surface of the opponent's skin is 99.75. Its bactericidal effect is better than 2% iodine, and no discomfort was found when applied to the skin, mucous membranes and wounds.

Embodiment 3

[0026] 1) Iodine 1.0%;

[0027] 2) Polyvinylpyrrolidone 4.0%;

[0028] 3) Potassium iodide: 0.3%;

[0029] 4) Sodium dodecylbenzenesulfonate 0.2%;

[0030] 5) Purified water 94.5%.

[0031] After the above components are mixed, they are fully stirred to make a medicinal solution. In a laboratory test, the effect is 7 minutes, and the killing rate to Escherichia coli is 99.95; the killing rate to Candida albicans is 99.99; the killing rate to Staphylococcus aureus The rate is 99.96; the action time is 1 minute, and the rate of killing natural bacteria on the surface of the opponent's skin is 99.77. Its bactericidal effect is better than 2% iodine, and no discomfort was found when applied to the skin, mucous membranes and wounds.

[0032] Above embodiment carries out acute oral sex test to male and female SD kind rat, oral LD 50 >5000mg / kgBW, which belongs to the actual non-toxic level. In the subacute toxicity test, no harmful effects greater than 1000mg / kgBW were found; ...

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PUM

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Abstract

The invention relates to disinfectant comprising the following components by weight percent: 0.1 to 1.0 percent of iodine, 0.4 to 4.0 percent of polyvinylpyrrolidone, 0.03 to 0.3 percent of potassium iodide, 0.02 to 0.2 percent of sodium dodecyl benzene sulfonate and 94.50 to 99.45 percent of purified water. The invention is a disinfectant which has strong sterilization efficacy, high safety, good stability and low corrosiveness and irritability, can be used for the disinfection of the skin, mucous membranes and wounds and has low effective iodine content.

Description

【Technical field】 [0001] The invention relates to medical preparations containing inorganic active ingredients, iodine and its compounds, especially a disinfectant. 【Background technique】 [0002] At present, the most popular detoxification solution on the market in our country is iodine-containing disinfectant, most of which is iodine. As we all know, iodine belongs to the halogen group, and it has two sides, just like a double-edged sword: on the one hand, it has the strong properties shared by the halogen group elements. Oxidizing properties, it has a strong ability to kill bacteria and viruses, and is an efficient disinfection element. On the other hand, it is highly corrosive and irritating and can only be used for skin disinfection, not mucous membrane and wound disinfection. If it is not handled properly, it will cause harm to human or animal bodies. For a long time, people have not been able to handle the duality of iodine to an optimal state, that is, to maximize t...

Claims

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Application Information

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IPC IPC(8): A61K33/18A61K47/32A61P31/04A61P17/00A61P17/02
Inventor 吴岗
Owner 吴岗
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