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Quality detection method of red tangerine peel capsule

A quality inspection method and capsule technology, which can be used in capsule delivery, measuring devices, pharmaceutical formulations, etc., can solve the problems of high content of ineffective ingredients, low content of active ingredients, and patients feel pain, and achieve low content of ineffective ingredients and stable efficacy. , good therapeutic effect

Active Publication Date: 2012-05-23
SICHUAN MEDCO PHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But this medicine is owing to be traditional pill, directly pulverizes and makes with crude drug, so has following shortcoming: 1, active ingredient content is low, and onset of effect is slow, and curative effect is poor; ; 3. The drug is exposed, directly stimulates the taste buds, produces bad taste, and the patient feels pain; 4. The excipients contain a lot of honey, etc., which are not suitable for patients with diabetes, hyperlipidemia, and obesity

Method used

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  • Quality detection method of red tangerine peel capsule
  • Quality detection method of red tangerine peel capsule
  • Quality detection method of red tangerine peel capsule

Examples

Experimental program
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Effect test

Embodiment Construction

[0088] Prepare materials according to the following weight:

[0089] Orange red 166.7g, tangerine peel 111g, French pinellia 83g, tuckahoe 111g, licorice 55.5g, platycodon 83g, bitter almond 111g, fried perilla seed 83g, aster 83g, coltsfoot 55.5g, melon peel 111g, zhejiang fritillary 111g , Rehmannia glutinosa 111g, Ophiopogon japonicus 111g, gypsum 111g.

[0090] Take the dried tangerine peel, crush it into fine powder, sieve, and set aside.

[0091] The remaining fourteen medicinal materials are mixed, the effective ingredients are extracted with a solvent, and then the extract is made into a thick paste; the specific steps are: add water to decoct twice, add water 5 times the weight of the medicinal material for the first time, soak for 0.5 hours, and decoct 1.5 hours; add water 4 times the weight of the medicinal material for the second time, and cook for 1 hour. Combine the two decoction liquids, filter, and concentrate the filtrate under reduced pressure to form a thick past...

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Abstract

The invention discloses a quality detection method of a red tangerine peel capsule, which is divisional application of Chinese patent application CN 200710048402.9. The quality detection method comprises the steps of character identification and inspection and content measurement, wherein identification refers to identify effective ingredients of gypsum in the product by a chemical reaction method as well as effective ingredients of exocarpium citrl grandis, dried tangerine peel, licorice and thunberg fritillary bulb in the product by thin-layer chromatography; and content measurement refers to measure content of hesperidin in the product by high performance liquid chromatography. The quality detection method of the invention has strong specificity for the thin layer identification methodon traditional Chinese medicinal materials of the product such as exocarpium citrl grandis, dried tangerine peel, licorice and thunberg fritillary bulb, good repeatability, clear spot developing and no interference to negative control; the solvent used in a content measurement method has no influence on the obtained measuring result; the sample solution prepared by a formulated method is stable; and the measurement method has good repeatability and high accuracy, and RSD in a sample recovery test is 0.89%, thus meeting the specified requirement.

Description

[0001] The original application number of this divisional application is 200710048402.9, the filing date is February 1, 2007, and the title of the invention is "A modified preparation of orange pill and its preparation method and quality inspection method". Technical field [0002] The invention relates to a traditional Chinese medicine preparation, in particular to a modified preparation of orange pill and a preparation method and quality inspection method thereof. Background technique [0003] The 90th edition of "Chinese Pharmacopoeia" contains Juhong Pills, which is one of the most widely used Chinese patent medicines for relieving cough and reducing phlegm. The prescription is made up of the addition and subtraction of the four Qingjin Jianghuo decoction in the volume of "Gujin Medical Jian" by Ming Gong Xin. The prescription is rigorous and integrates the effects of clearing the lung, removing dampness, widening the chest, regulating qi, nourishing yin, clearing heat, promoti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/48A61P11/10A61P11/14G01N30/90G01N30/02A61K33/06
Inventor 王卫张祝君李彦
Owner SICHUAN MEDCO PHARML
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