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Chinese medicinal composition for relieving pain and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formula, non-central analgesic, etc., can solve the problems of addiction, respiratory depression, drowsiness, constipation, etc., and achieve high safety, fast onset, The effect of enhancing the potency of the drug

Active Publication Date: 2010-12-29
杜江
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as cancer pain, the morphine drugs currently used clinically are addictive, and have adverse reactions such as respiratory depression, lethargy, and constipation

Method used

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  • Chinese medicinal composition for relieving pain and preparation method thereof
  • Chinese medicinal composition for relieving pain and preparation method thereof
  • Chinese medicinal composition for relieving pain and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Prescription composition:

[0049] 5 parts of musk, 10 parts of dried blood, 5 parts of toad venom, 10 parts of honeycomb, 5 parts of nuxychonzi, 20 parts of gardenia, 20 parts of araceae, 10 parts of camphor

[0050] Preparation method of ointment:

[0051] 1) Moschus, dried blood, toad venom, and camphor are pulverized to 80 mesh to obtain powdered medicinal materials;

[0052] 2) The remaining medicinal flavors were reflux extracted with 60% ethanol for 3 times, each time for 30 minutes, filtered and concentrated to a relative density of 1.20-1.30 (50°C) to obtain a concentrated solution;

[0053] 3) Combine the above-mentioned powder-making medicinal materials with the concentrated solution, stir well, dry, pulverize into fine powder, add appropriate amount of liquid paraffin to grind into a paste, add vaseline in stages, mix and grind until uniform.

Embodiment 2

[0055] Prescription composition:

[0056] 8 parts of musk, 15 parts of dried blood, 8 parts of toad venom, 15 parts of honeycomb, 10 parts of nuxychonzi, 18 parts of gardenia, 18 parts of araceae, 5 parts of camphor

[0057] Preparation method of patch:

[0058] 1) Moschus, dried blood, toad venom, and camphor are pulverized to 100 mesh to obtain powdered medicinal materials;

[0059] 2) The remaining medicinal flavors were reflux extracted with 70% ethanol for 3 times, each time for 45 minutes, filtered and concentrated to a relative density of 1.20-1.30 (50°C) to obtain a concentrated solution;

[0060] 3) Combine and stir the above-mentioned powdered medicinal materials and concentrated solution, mix them with sodium polyacrylate base and auxiliary materials such as glycerin to form a paste, and apply it on the non-woven backing material to make a traditional Chinese medicine patch.

experiment example 1

[0061] Experimental example 1: the clinical trial of the pain-relieving traditional Chinese medicine composition of the present invention

[0062] 1 clinical data

[0063] 160 cases were clinically observed (including 140 cases in the experimental group and 20 cases in the control group). The patients were randomly divided into two groups, and the ointment of Example 1 of the present invention and Yunnan Baiyao ointment were applied externally respectively. The general clinical data are shown in Table 1, and the types of injuries are shown in Table 2.

[0064] Table 1. General clinical data

[0065]

[0066] Table 2. Damage categories

[0067] Classification

soft tissue injury

joint dislocation

fracture

test group

98

15

27

control group

12

3

5

total

110

18

32

[0068] 2 treatment methods

[0069] 2.1 The ointment of Example 1 of the present invention is evenly applied to the af...

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Abstract

The invention relates to a Chinese medicinal composition for relieving pain, which comprises the following raw material medicaments in part by weight: 1 to 30 parts of musk, 1 to 30 parts of dragon's blood, 1 to 30 parts of toad venom, 1 to 30 parts of honeycomb, 1 to 30 parts of nux vomica, 1 to 30 parts of fructus gardeniae, 1 to 30 parts of rhizoma arisaematis and 1 to 30 parts of camphor. The Chinese medicinal composition of the invention belongs to external antalgica, and has the advantages of safe use and obvious effect of relieving pain.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for relieving pain and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Pain is a complex physiological and psychological activity, and it is one of the most common clinical symptoms. It includes the pain sensation caused by noxious stimuli acting on the body and the body's pain response to noxious stimuli. Pain can be used as a warning that the body is injured, causing a series of defensive protective reactions of the body. And some long-term severe pain has become a kind of unbearable torture to the body. For example, for cancer pain, morphine drugs currently used in clinical practice are addictive, and have adverse reactions such as respiratory depression, lethargy, and constipation. [0003] According to traditional Chinese medicine, there are many causes of pain, some are due to congestion, some are due to bloc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P25/04A61P29/02A61K31/125A61K35/55A61K35/56A61K35/64A61K35/65
Inventor 杜江
Owner 杜江
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