Sterilizing type medical ultrasonic coupling agent and preparation method thereof

An ultrasonic couplant, disinfection and sterilization technology, applied in the field of couplant, can solve the problems of no chloramphenicol and polyhexamethylene guanidine, no skin detection, no disinfection and sterilization effect, etc., and achieves good sound conduction performance and fast speed. And long-term sterilization and disinfection function, bright color effect

Inactive Publication Date: 2011-07-27
QINGDAO MINGYAOTANG MEDICAL TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] The currently used medical ultrasonic coupling agent has the following defects: one is that the components used are relatively complex or the cost of the components is relatively high; the other is that there is no disinfection and sterilization effect; skin detection
In order to overcome the problems existing in the existing coupling agent, the present invention proposes a coupling agent composed of chloramphenicol, polyhexamethylene guanidine and other auxiliary materials. report, and there is no report on the formation of coupling agent between the two and auxiliary materials

Method used

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  • Sterilizing type medical ultrasonic coupling agent and preparation method thereof
  • Sterilizing type medical ultrasonic coupling agent and preparation method thereof
  • Sterilizing type medical ultrasonic coupling agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] 1. Feeding: according to the proportion of the formula, feed the material with a total amount of 1000g coupling agent, namely:

[0046]

[0047]

[0048] 2. Preparation method:

[0049] 1) Weighing various ingredients according to the prescription quantity;

[0050] 2) Add 5.0g of carbomer into 400g of deionized water, and stir in a water bath at 50-68°C until completely dissolved, and leave it;

[0051] 3) 1.0 g of 20% polyhexamethylene biguanide is completely dissolved in 30.0 g of glycerol, and left in place;

[0052] 4) Dissolve 3.0 g of chloramphenicol completely in 30 g of propylene glycol, and leave it;

[0053] 5) The 1.5g sodium hydroxide taken by weighing is completely dissolved in deionized water, and left

[0054] 6) Mix the mixed solution obtained in step 3) and 4) evenly, then add to the carbomer solution obtained in step 2) and stir until uniform, then add the remaining deionized water, and slowly add sodium hydroxide solution under stirring Sti...

Embodiment 2

[0075] 1. Feeding: according to the proportion of the formula, feed the material with a total amount of 1000g coupling agent, namely:

[0076]

[0077] 2. Preparation method:

[0078] 1) Weighing various ingredients according to the prescription quantity;

[0079] 2) Add 7.0g of carbomer into 400g of deionized water, stir in a water bath at 50-68°C until completely dissolved, and leave it;

[0080] 3) 5.0 g of 20% polyhexamethylene biguanide is completely dissolved in 50.0 g of glycerol, and left in place;

[0081] 4) chloramphenicol 2.5g is completely dissolved in 50g of propylene glycol, and left;

[0082] 5) Dissolve 2g of sodium hydroxide weighed in 100g of deionized water completely, and leave

[0083] 6) Mix the mixed solution obtained in step 3) and 4) evenly, then add to the carbomer solution obtained in step 2) and stir until uniform, then add the remaining deionized water, and slowly add sodium hydroxide solution under stirring Stir until uniform, make a neutr...

Embodiment 3

[0086] 1. Feeding: according to the proportion of the formula, feed the material with a total amount of 1000g coupling agent, namely:

[0087]

[0088] 2. Preparation method:

[0089] 1) Weighing various ingredients according to the prescription quantity;

[0090] 2) Add Carbomer 9.0 to 400g of deionized water, stir in a water bath at 50-68°C until completely dissolved, and leave it;

[0091] 3) 2.5 g of 20% polyhexamethylene biguanide is completely dissolved in 70.0 g of glycerol, and left in place;

[0092] 4) Dissolve 2.0 g of chloramphenicol completely in 70 g of propylene glycol and leave it there;

[0093] 5) Dissolve the 2.5g sodium hydroxide taken by weighing in 100g deionized water completely, leave

[0094] 6) Mix the mixed solution obtained in step 3) and 4) evenly, then add to the carbomer solution obtained in step 2) and stir until uniform, then add the remaining deionized water, and slowly add sodium hydroxide solution under stirring Stir until uniform, ma...

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Abstract

The invention relates to a sterilizing type medical ultrasonic coupling agent and a preparation method thereof. The coupling agent contains the following active ingredients: polyhexamthylene guanidine-derivatives and chloramphenicol. A test proves that the coupling agent provided by the invention has the effects of transmitting sound, lubricating and preventing cross-infection, and the preparation method is simple and environment-friendly.

Description

technical field [0001] The invention relates to a couplant, in particular to a medical ultrasonic couplant with disinfection and sterilization functions and a preparation method thereof. Background technique [0002] The frequency of medical ultrasound is 2.5-5M, which cannot be transmitted in the air. If there is air between the probe and the skin, the ultrasonic wave will return as soon as it encounters the air, and cannot enter the human body, so it cannot be used for inspection. Therefore, it is necessary to apply a layer of couplant on the skin earlier, so as to eliminate the air between the probe and the skin. [0003] The coupling agent is a water-soluble polymer colloid with good performance. It can eliminate the air between the probe and the skin to make the image clear. It has no damage to the skin, no irritation, no toxicity, no allergies, and no pollution. [0004] In traditional ultrasonic diagnosis, in order to avoid cross-infection of the cavity mucosa, cond...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 李育强孙士学
Owner QINGDAO MINGYAOTANG MEDICAL TECH DEV
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