Novel blood pressure reducing composition

Abstract

The invention relates to a novel blood pressure reducing composition. The blood pressure reducing composition is a medicinal composition of which active ingredients are any one or two of aliskiren and a medicinal salt thereof, a hydrate, a calcium channel blocker (CCB), an angiotensin type 1 (AT1) receptor blocker (ARB), an angiotensin-converting enzyme inhibitor (ACEI), hydrochlorothiazide and the like. The composition can be prepared into oral tablets or capsules and is used for treating hypertension, and the curative effect is superior to the blood pressure reducing effect of the independent aliskiren.

Description

technical field [0001] The invention is a novel blood pressure lowering composition, which belongs to the technical field of medicine. Background technique [0002] Hypertension is the most prevalent cardiovascular disease in the world today, and it is also an important risk factor for coronary heart disease, stroke and renal failure. Patients with hypertension not only have increased blood pressure and abnormal hemodynamics, but also often accompanied by It is a systemic disease with sugar and lipid metabolism disorders and damage to target organs such as the heart, brain, and kidneys. There are many antihypertensive drugs clinically, including diuretics, β-blockers, angiotensin converting enzyme inhibitors (ACE-I), angiotensin II (AT II) receptor antagonists, calcium antagonists and α - blockers. However, they all have certain limitations and side effects in use. Therefore, antihypertensive drugs with small side effects, good tolerance, and stable efficacy will be widel...

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