Medicament for preventing and curing avian infectious laryngotracheitis and preparation method thereof

A technology of tracheitis and drugs, applied in the field of drugs composed of extracts, can solve the problems of exacerbation of mortality, failure to reach, secondary infection of E. coli, etc., and achieve good curative effect

Inactive Publication Date: 2012-02-22
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the late stage of the disease often causes secondary infection of E. coli and

Method used

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Embodiment Construction

[0016] 12 parts of Shandougen, 10 parts of Scutellaria baicalensis, 12 parts of Shegan, 10 parts of Radix Isatidis, 8 parts of bellflower, and 6 parts of licorice.

[0017] Accurately weigh each drug according to the above ratio, percolate with 10 times the amount of 70% ethanol, and concentrate the percolation solution under reduced pressure to form an extract; add 6 times the amount of water to decoct the dregs of the medicine for 1 hour, and then add 4 times the amount of water to decoct Boil for half an hour, filter, combine the filtrates, centrifuge at 3000r / min to remove precipitated impurities, then concentrate to a 2:1 concentrate (that is, 2 grams of raw medicinal materials are concentrated to 1ml), and dry it into a powder by a freeze dryer. Combine water extract and alcohol extraction, add 40% microcrystalline cellulose as filler, 15% cross-linked polyvinylpyrrolidone and 7% low-substituted hydroxypropyl cellulose as joint disintegrating agent, 1% colloidal bismuth ...

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PUM

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Abstract

The invention discloses a medicament for preventing and curing avian infectious laryngotracheitis and a preparation method thereof. The medicament is prepared by the following traditional Chinese herbs by weight: 12 parts of subprostrate sophora, 10 parts of scutellaria baicalensis, 12 parts of blackberry lilies, 10 parts of isatis roots, 8 parts of platycodon grandiflorum and 6 parts of liquorice. The preparation method of the medicament comprises the following steps: first extracting the herbs with ethanol to obtain extract; adding water to dregs of the decoction after ethanol extraction and extracting, and then concentrating and drying to obtain water extract powder; mixing with the extract and obtaining the needed medicament, or adding microcrystalline cellulose to serve as a filler and a joint disintegrating agent and making into dispersible tablets. The medicament for preventing and curing the avian infectious laryngotracheitis gives full consideration to anti-inflammation, resistance to secondary infection, medicament guidance to lung channels and other aspects, has considerably good curative effects, and also can improve absorption of the insoluble medicament, shorten the time of the medicament for taking effect and improve bioavailability of the insoluble medicament.

Description

technical field [0001] The invention relates to a veterinary medicine, specifically a medicine for preventing and treating chicken infectious laryngotracheitis, which is composed of extracts of various herbal medicines. Background technique [0002] Infectious laryngotracheitis (ILT) is a highly contagious upper respiratory tract infection caused by an α-herpes virus, namely infectious laryngotracheitis virus (ILTV). The sickness rate of this disease is 100% when the acute outbreak occurs, and the mortality rate is as high as 5-70%. : 50-52; chicken infectious laryngotracheitis can drop up to 35% in laying hens egg production, see: "diagnosis of chicken infectious laryngotracheitis" Hu Renshan, "Chinese Journal of Veterinary Medicine", 1992, 18 (7): 9-10, is one of the important diseases that endanger the poultry industry. In order to effectively control the occurrence of this disease, scholars at home and abroad have carried out a lot of research work in recent years, and...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P31/22A61P11/00
Inventor 罗永江辛蕊华郑继芳梁歌谢家声王贵波罗超应李绵宇
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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