Unibract fritillary bulb and loquat leaf medicinal composition and preparation method thereof

The technology of Chuanbei loquat and composition is applied in the field of traditional Chinese medicine composition and preparation technology thereof, and achieves the effects of enhanced drug efficacy, convenient manufacture and simple preparation technology

Inactive Publication Date: 2012-02-29
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Another object of the present invention is to develop a method for preparing the Chuanbei loquat composition with excellent performance and in line with the standard of the "Pharmacopoeia of the People's Republic of China" by using the four medicinal materials in the composition as raw materials, and overcome the problem of making The disadvantages of high cost and low bioavailability improve product quality, reduce costs, facilitate taking, and better meet medical needs and the utilization of raw materials

Method used

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  • Unibract fritillary bulb and loquat leaf medicinal composition and preparation method thereof
  • Unibract fritillary bulb and loquat leaf medicinal composition and preparation method thereof
  • Unibract fritillary bulb and loquat leaf medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Use 65g of Fritillaria chinensis, 65g of Platycodon grandiflorum, 430g of loquat leaves, 0.5g of menthol and four herbs as raw materials; crush 65g of Fritillaria chinensis into fine powder passing through a 100-mesh sieve for later use, and crush 65g of Platycodon grandiflorum into fine powder passing through a 100-mesh sieve. powder, take 48g of bellflower fine powder for later use, mix the remaining bellflower powder with 430g of loquat leaves, add water and decoct twice, add 10 times the amount of water of the mixture for the first time, and cook for 1 hour; add 8 times of the mixture for the second time amount of water, decocted for 1 hour, filtered several times, combined the filtrates, and stood still for 12 hours, took the supernatant and concentrated it to a clear paste with a relative density of 1.20-1.25 (60°C), and added 48g of platycodon grandiflorum to the clear paste. Powder, mix, dry, grind, add Fritillaria fine powder, mix, granulate, dry, add menthol 0....

Embodiment 2

[0074] Use 50g of Fritillaria chinensis, 50g of Platycodon grandiflorum, 330g of loquat leaves, 0.35g of menthol and four herbs as raw materials; crush 50g of Fritillaria chinensis into fine powder passing through a 120-mesh sieve for later use, and crush 50g of Platycodon grandiflorum into fine powder passing through a 120-mesh sieve. powder, take 36.9g bellflower fine powder for later use, mix the remaining bellflower powder with 330g loquat leaves, add water and decoct twice, add 8 times the amount of water of the mixture for the first time, and cook for 1 hour; add 6 times of the mixture for the second time times the amount of water, decocted for 0.5 hours, filtered several times, combined the decoction, stood still for 10 hours, took the supernatant and concentrated it to a clear paste with a relative density of 1.20-1.25 (60°C), and added 36.9 g bellflower fine powder, mix well, dry, grind finely, add Chuan Fritillaria fine powder, mix well, granulate, dry, add menthol 0....

Embodiment 3

[0076] Use 90g of Fritillaria chinensis, 90g of Platycodon grandiflorum, 600g of loquat leaves, 0.7g of menthol and four herbs as raw materials; crush 90g of Fritillaria chinensis into fine powder passing through a 150 mesh sieve for later use, and crush 90g of Platycodon grandiflorum into fine powder passing through a 150 mesh sieve. powder, take 66.5g bellflower fine powder for later use, mix the remaining bellflower powder with 600g loquat leaves, add water and decoct 3 times, add 12 times the amount of water of the rest bellflower powder and loquat leaf mixture for the first time, and cook for 1.5 hours; Add 10 times the amount of water of the mixture for the second time, decoct for 1 hour; add 8 times the amount of water of the mixture for the third time, decoct for 0.5 hours, filter in several times, combine the decoctions, let stand for 14 hours, and take the supernatant Concentrate the liquid to a clear paste with a relative density of 1.20-1.25 (60°C), add 66.5g of bel...

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Abstract

The invention relates to a unibract fritillary bulb and loquat leaf medicinal composition and a preparation method thereof. Four Chinese herbal medicines, namely unibract fritillary bulb, platycodon grandiflorum, loquat leaf, and menthol crystal are selected and the preparation method comprises the following steps of: crushing unibract fritillary bulb into fine powder for later use, crushing platycodon grandiflorum powder into fine powder, taking a certain amount of platycodon grandiflorum fine power for later use, mixing residual platycodon grandiflorum powder and loquat leaf, adding water and decocting, filtering for different times, mixing filtrates, standing, taking supernate, concentrating to obtain plaster, adding platycodon grandiflorum fine power, uniformly mixing, drying, grinding, adding unibract fritillary bulb fine powder, mixing uniformly, pelletizing, drying, adding menthol crystal and auxiliary materials, mixing uniformly, and preparing various formulations according to clinical requirements. The medicine is prepared from non-toxic and pure Chinese herbal medicines, the medicine prepared by the process can be absorbed easily, the utilization rate of active ingredients of the medicine is higher, and the medicine is convenient to take and carry, and is low in preparation cost. If 70 percent ethanol is added into one third unibract fritillary bulb fine power for extraction and then the subsequent operation is performed, the prepared medicine has better curative effects.

Description

[0001] This application is a divisional application of application number 200810135060.9, the filing date is 2008.7.29, and the invention name is Chuanbei loquat pharmaceutical composition and its preparation method. technical field [0002] The invention relates to a traditional Chinese medicine composition and the field of preparation technology thereof, more specifically to a Chuanbei loquat medicinal composition and a preparation method thereof. Background technique [0003] Chuanbei loquat syrup published in the 2000 edition is a commonly used medicine traditionally used to treat colds, coughs and bronchitis. Its prescription is 45ml of Chuanbeimu liquid extract, 45g of bellflower, 300g of loquat leaves, and 0.34g of menthol. The preparation method is to take 45g of Fritillaria sichuanensis fluid extract, grind it into a coarse powder, follow the percolation method (Appendix 10) under the liquid extract and extract, use 70% ethanol as solvent, and soak it for 5 days. , ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P11/00A61P11/14
Inventor 唐德江陈犁
Owner 重庆希尔安药业有限公司
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