Pharmaceutical composition for treating dermatitis and eczema and preparation method thereof

A composition and drug technology, applied in the directions of drug combination, pharmaceutical formula, hydroxyl compound active ingredient, etc., can solve the problems of drug and patient's skin redness, patient discomfort, etc., and achieve the effect of obvious curative effect, not easy to recur, and moisturizing the skin.

Inactive Publication Date: 2012-03-21
JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional medicines for treating dermatitis and eczema include Piyankang, fluocinonide acetate, etc. The traditional fluocinonide acetate is composed of a single fluocinonide acetate raw material and an emulsion matrix. Although it has a certain effect, the contact surface between the medicine and the patient's skin will be red and swollen phenomenon, causing discomfort to the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Among the present invention, the preparation method of described a kind of pharmaceutical composition for the treatment of dermatitis, eczema comprises the steps:

[0017] ① Weigh raw materials: 0.01g of fluocinolone acetate and 0.5g of borneol, mix well and pulverize into fine powder, pass through a 100-300 mesh sieve, and set aside;

[0018] ② Weigh the emulsion base: 8 g glyceryl monostearate, 35 g beeswax, 10 g paraffin, 1 g stearic acid, 25 g liquid paraffin, 10 g white petrolatum, 1 g aluminum distearate, calcium hydroxide 0.2 g, ethyl paraben 0.2 g, distilled water 20 g. Put glyceryl monostearate, beeswax, paraffin, and stearic acid in an evaporating dish, heat and melt on a water bath, then add white petrolatum, liquid paraffin, aluminum distearate, and heat to 60-80°C. In addition, dissolve calcium hydroxide and ethylparaben in distilled water and heat to 60-80°C, add to the above oil phase solution, and keep stirring in the same direction while adding until ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating dermatitis and eczema, which comprises fluocinolone acetonide, borneol, and a emulsion base. The advantage of the invention is that borneol is used in the medicament, which has antibiotic and pain-relieving effect, and has cool and refreshing feeling that makes patient feel comfortable. The pharmaceutical composition of the invention has a simple process, is convenient for preparation and application, has significant curative effect, is not easy to cause recurrence, can moisten skin, and is applicable to dermatitis, eczema, psoriasis, non-specific pruritus ani and reproductive organ pruritus.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating dermatitis and eczema and a preparation method thereof. Background technique [0002] Dermatitis and eczema are often used synonymously to refer to a type of skin inflammation that represents an allergic reaction of the skin to a variety of substances, including chemicals, proteins, bacteria and fungi. The term eczema has no special meaning, while dermatitis has a defined meaning. If dermatitis is used instead of eczema as a diagnostic term, it refers to a combined dermal-epidermal reaction, which can be acute, subacute, or chronic. All three can exist in combination. [0003] At present, the treatment methods for dermatitis and eczema mostly adopt hormone therapy. The traditional medicines for treating dermatitis and eczema include Piyankang, fluocinonide acetate, etc. The traditional fluocinonide acetate is composed of a s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/58A61K31/045A61K9/06A61P17/00
Inventor 刘德胜
Owner JILIN AODONG GROUP DALIAN PHARMACEUTICAL CO LTD
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