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Medical implant with bioactive material and method of making the medical implant

A bioactive, implant technology, applied in the field of medical implants on the second side, can solve problems such as lack of effective bone conduction arrangement

Inactive Publication Date: 2012-03-21
WARSAW ORTHOPEDIC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some implants include structures properly shaped to accommodate growing bone and support musculoskeletal tissue, but lack effective placement of osteoconductive or osteoinductive materials to support bone growth throughout or in the most favorable location

Method used

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  • Medical implant with bioactive material and method of making the medical implant
  • Medical implant with bioactive material and method of making the medical implant
  • Medical implant with bioactive material and method of making the medical implant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0035] An exemplary medical implant 1 was prepared and evaluated as follows. An exemplary manufacturing method includes providing a porous scaffold 10. The porous scaffold can be formed of PEEK particles with a size of 100 to 600 microns. The exemplary porous scaffold 10 is made with 300-600 micron PEEK particles that are ground from standard PEEK pellets using a polymer grinder and sieved with a sieve to achieve the desired particle size. The PEEK pellets are weighed, and then the PEEK pellets are placed in a compression mold. The amount of PEEK particles placed in the compression mold is 0.3-0.4 grams. The inner diameter of the mold is about 13mm and the height is 10mm. The mold includes a circular bottom and top with a diameter of 12.9 mm and a protrusion of 5 mm for compressing the PEEK particles in the mold in response to pressure applied to the top and bottom of the mold.

[0036] The Carver press is used to compress the PEEK pellets in the compression mold. The Carver...

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Abstract

Embodiments of the invention include a medical device and a method of manufacturing a medical device having a porous scaffold in combination with a bioactive material. In some embodiments, particularly limited thicknesses of the bioactive material are applied within pores of the porous structure.

Description

Background technique [0001] It is advantageous in many orthopedic applications that bone grows into, around and / or even completely through implants designed to support or replace various musculoskeletal structures. There are many porous structures in the prior art, which are designed to contain growing bone or other musculoskeletal tissues. In conjunction with and in addition to these structures, a variety of bioactive materials are known to support or promote the growth of bone and other tissues. Substances that obediently support the growth of bones are known to be osteoconductive. Osteoconducting substances obediently support bone ingrowth by benefiting the growth of vascular structures and osteoprogenitor cells necessary for bone growth. Substances that actively stimulate or promote bone growth are known as osteogenic or osteoinductive. Specifically, osteogenic materials stimulate bone formation, while osteoinductive materials support cell division of undifferentiated per...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/12A61L27/16A61L27/54A61L27/56
CPCA61L27/16A61L27/56A61L2300/412A61L27/12A61L2300/606A61L27/54A61P19/00C08L29/12
Inventor H·萨维奇-埃里克森
Owner WARSAW ORTHOPEDIC INC