Preparation formula of paracetamol oral solution capable of being prepared into frozen state for patient to take

Abstract

The invention relates to a preparation formula of a paracetamol oral solution which can be prepared into a frozen state for a patient to take. The preparation formula comprises 0.5-8.0% (g / L) of a main medicine paracetamol, 2.0-40.0% (g / L) of a high-hydrophilicity cyclodextrin derivative, 50.0-96.0% (g / L) of water, and 0-20.0% (g / L) of other auxiliary components. The oral solution prepared with the formula has a good taste. The oral solution can be taken as an oral solution, and can be frozen into a solid in a freezing environment of a domestic refrigerator, wherein the temperature can be set as 0 to -20 DEG C. Then the solid can be taken. Therefore, medication adaptability of patients, especially children, can be improved.

Description

technical field [0001] The invention relates to the preparation of a paracetamol oral solution formula that can be taken in frozen form, and in particular relates to a preparation method different from the conventional paracetamol oral solution. The acetaminophen oral solution prepared by the present invention has a good taste, and patients can take it in the form of oral solution, and can also be frozen under the environment of the refrigerator freezer (the temperature can be set within the range of 0~-20° C.) used by ordinary families. Congeal before taking. To achieve the purpose of enhancing the medication compliance of patients, especially children. Background technique [0002] Acetaminophen, also known as paracetamol, is an antipyretic and analgesic drug of the acetanilide class. Its antipyretic effect is similar to that of acetylsalicylic acid, and has moderate to mild analgesic effect. As an antipyretic and analgesic, it has definite curative effect, less toxic a...

AI Technical Summary

Problems solved by technology

The oral liquid prepared by the above method cannot be frozen into a complete solidified state in the household refrigerator