Method for measuring content of ginsenoside Rg1 and Rb1 in Xinshu capsule

A technology of ginsenosides and a determination method is applied in the quantitative determination of effective components of Xinshu capsules and the field of traditional Chinese medicine preparations, which can solve the problems of high cost, long time consumption, poor separation degree and the like, and achieves low cost, simple operation and high recovery rate. Effect

Active Publication Date: 2012-05-02
JILIN BENCAOTANG PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] The present invention is to solve the active ingredient ginsenoside Rg in the prior art Zhongshu capsule 1 and Rb 1 The quantitative determination method of the method has poor resolution, and needs to detect separately and detect the technical problems of long time and high cost. A kind of ginsenoside Rg in Xinshu capsules is provided. 1 and Rb 1 The determination method of the content, which is obtained through the inventor's years of unremitting efforts and creative experimental design

Method used

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  • Method for measuring content of ginsenoside Rg1 and Rb1 in Xinshu capsule
  • Method for measuring content of ginsenoside Rg1 and Rb1 in Xinshu capsule
  • Method for measuring content of ginsenoside Rg1 and Rb1 in Xinshu capsule

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Embodiment 1

[0021] 1. Prescription

[0022] Salvia 62.5 parts Sanqi 50 parts borneol 50 parts

[0023] Rattan Albizia 250 parts, Woody 50 parts, Styrax 12.5 parts.

[0024] Second, the method

[0025] 125 parts of Albizia vine, add water and decoct twice, the amount of water is 8 times the weight of the medicinal material, the time is 2 hours, filter, combine the second filtrate, concentrate into a thick paste; take Danshen, Panax notoginseng, wood fragrance and the remaining amount The rattan albizia, powdered into a coarse powder, mixed with the above thick paste, dried, and crushed into a fine powder; the borneol was ground into fine powder, mixed into the above fine powder, sieved, and mixed; added styrax, mixed evenly, and an appropriate amount of starch, Spray an appropriate amount of ethanol (about 120ml) to make a soft material, pass through a 16-mesh sieve to make granules, and dry at 50°C for 1 hour.

[0026] 3. Identification

[0027] This product is a capsule, the contents...

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Abstract

The invention relates to a method for measuring content of ginsenoside Rg1 and Rb1 in a Xinshu capsule, solves the technical problems that components of a raw material medicine of the Xinshu capsule are difficult to separate, and the content of ginsenoside Rg1 and Rb1 in the Xinshu capsule cannot be simultaneously measured by a high performance liquid chromatography, which are expected to be solved but not solved for a long time, and provides a gradient elution high performance liquid chromatography to successfully separate the ginsenoside Rb1 and Rg1 from other peaks. The method is easy and convenient to implement, low in cost (about 200 yuan for each sample) and short in detection time (about 70 minutes for each sample). The method can be used as a quantitative detection method for standards in a Xinshu capsule medicine standard.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and more specifically the invention relates to the technical field of quantitative determination of active ingredients in Xinshu capsules. Background technique [0002] Xinshu Capsule is a new medicine developed by Jilin Tianyao Bencaotang Pharmaceutical Co., Ltd. after reforming the traditional product Xinshu Pills. become. It has the effects of forming qi, activating blood circulation, clearing orifices, and relieving depression, and is used for chest tightness, shortness of breath, and angina pectoris caused by coronary heart disease. Ginsenoside Rg 1 , Rb 1 It is the main active ingredient of ginseng in the prescription. In order to control the quality of the drug and ensure the curative effect, it is necessary to control the ginsenoside Rg in the prescription. 1 , Rb 1 Determination is carried out to ensure that the content is within the specified range...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/88
Inventor 王怀生
Owner JILIN BENCAOTANG PHARMA
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