Compound preparation used for preventing and treating nephrotic syndrome hypoproteinemia, preparation method thereof, and application thereof

Abstract

The invention discloses a traditional Chinese medicine compound preparation used for treating nephrotic syndrome hypoproteinemia. Nephritic syndrome hypoproteinemia has clinical indications of plasma-albumin lower than 30g / L, lower extremities edema and hydrothorax and ascites with different degrees, poor appetite, hypodynamia, abdominal distention; or companied skin eczema, and bitter taste and dryness of mouths; or companied purplish mouth, lips or tongues, and purplish and expended sublingual venae. The compound preparation provides functions of spleen strengthening, kidney benefiting, blood circulation promoting, meridian obstruction removing, heat clearing, and dampness eliminating. The compound preparation is an oral preparation composed of an active component extract and medicinal auxiliary materials. The active component extract is at least extracted from black soybean, Mongolian milkvetch root, common yam rhizome, swordlike atractylodes rhizome, ligusticum, and leeches. The invention also discloses an extraction method of the active components and an application thereof in preparing medicines used for preventing and treating nephrotic syndrome hypoproteinemia.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method, in particular to a Chinese medicinal compound preparation for preventing and treating nephrotic syndrome hypoalbuminemia, a preparation method and application thereof. Background technique: [0002] Nephrotic syndrome is a relatively common clinical disease, and the incidence of primary nephrotic syndrome (except secondary nephrotic syndrome) accounts for about 30% of all chronic kidney diseases in my country. Hypoalbuminemia is one of the main features of nephrotic syndrome and is the main cause of nephrotic syndrome edema. The cause of hypoalbuminemia can be caused by abnormal loss of plasma protein from urine, and it is also related to abnormal protein catabolism, decreased protein synthesis, decreased intestinal protein absorption, and abnormal protein distribution in the body. [0003] Protein is the material basis of life. Albumin is the protein with t...

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Problems solved by technology

[0005] In addition, there are currently amino acid preparations administered intravenously or orally to improve hypoproteinemia, such as compound amino acid injection (3AA-18AA), compound amino acid granules, etc., which are mainly used for gastrointestinal dysfunction, various chronic liver diseases, and liver cirrhosis. Malnutrition caused by hypoalbuminemia, febrile acute disease, tuberculosis, hyperthyroidism and other chronic wasting diseases, as well as adjuvant treatment of tumor radiotherapy and chemotherapy, some scholars use it for hypoalbuminemia in patients with chronic renal failure and hemodialysis. See research reports on its use in hypoalbuminemia in nephrotic syndrome

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