Compound preparation used for preventing and treating nephrotic syndrome hypoproteinemia, preparation method thereof, and application thereof
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A technology for nephrotic syndrome and compound preparation, applied in the field of traditional Chinese medicine preparation and preparation, can solve the problems such as the research report on hypoproteinemia of nephrotic syndrome which has not been seen yet
Inactive Publication Date: 2012-06-06
上海海天医药科技开发有限公司
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[0005] In addition, there are currently amino acid preparations administered intravenously or orally to improve hypoproteinemia, such as compound amino acid injection (3AA-18AA), compound amino acid granules, etc., which are mainly used for gastrointestinal dysfunction, various chronic liver diseases, and liver cirrhosis. Malnutrition caused by
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Embodiment 1
[0027] The preparation of embodiment 1 active ingredient extract
[0030] 1. Weigh the black beans and leeches in proportion, mix and pulverize the black beans and leech powder, sieve to obtain a fine powder, then carry out ultrafine grinding to obtain 300 mesh black beans and leech mixed micropowder, and set aside;
[0031] 2. Weigh Scutellaria barbata, add 70% ethanol to reflux and extract; filter the medicinal liquid, concentrate the filtrate, dry under reduced pressure to obtain Scutellaria barbata extract powder.
[0032] 3. Weigh Atractylodes atractylodis and Angelica Sinensis in proportion, extract the volatile oil by steam distillation, and clathrate the volatile oil with β-cyclodextrin to obtain the volatile oil i...
Embodiment 2
[0035] Recipe: 40g of black beans, 200g of astragalus, 16g of atractylodes, 160g of yam, 40g of Hedyotis diffusa, 160g of Scutellaria barbata 40, 120g of Achyranthes bidentata, 25g of silkworm, 4g of leech
[0036] The preparation method of the extract of the active ingredient is the same as in Example 1 to obtain the extract B of the active ingredient.
[0039] The preparation method of the extract of the active ingredient is the same as in Example 1 to obtain the extract C of the active ingredient.
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Abstract
The invention discloses a traditional Chinese medicine compound preparation used for treating nephrotic syndrome hypoproteinemia. Nephritic syndrome hypoproteinemia has clinical indications of plasma-albumin lower than 30g/L, lower extremities edema and hydrothorax and ascites with different degrees, poor appetite, hypodynamia, abdominal distention; or companied skin eczema, and bitter taste and dryness of mouths; or companied purplish mouth, lips or tongues, and purplish and expended sublingual venae. The compound preparation provides functions of spleen strengthening, kidney benefiting, blood circulation promoting, meridian obstruction removing, heat clearing, and dampness eliminating. The compound preparation is an oral preparation composed of an active component extract and medicinal auxiliary materials. The active component extract is at least extracted from black soybean, Mongolian milkvetch root, common yam rhizome, swordlike atractylodes rhizome, ligusticum, and leeches. The invention also discloses an extraction method of the active components and an application thereof in preparing medicines used for preventing and treating nephrotic syndrome hypoproteinemia.
Description
Technical field: [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method, in particular to a Chinese medicinal compound preparation for preventing and treating nephrotic syndrome hypoalbuminemia, a preparation method and application thereof. Background technique: [0002] Nephrotic syndrome is a relatively common clinical disease, and the incidence of primary nephrotic syndrome (except secondary nephrotic syndrome) accounts for about 30% of all chronic kidney diseases in my country. Hypoalbuminemia is one of the main features of nephrotic syndrome and is the main cause of nephrotic syndrome edema. The cause of hypoalbuminemia can be caused by abnormal loss of plasma protein from urine, and it is also related to abnormal protein catabolism, decreased protein synthesis, decreased intestinal protein absorption, and abnormal protein distribution in the body. [0003] Protein is the material basis of life. Albumin is the protein with t...
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