The invention provides an albumin peptide beverage, a preparation method and an application in improvement of plasma albumin indexes. The albumin peptide beverage comprises the following raw materials by weight: egg white, green papaya, pineapple, momordica grosvenori, cranberry, vitamin B6, vitamin B12, nicotinic acid, sucralose, citric acid, maltodextrin, fructo-oligosaccharide and water. Fresh fruits such as green papaya, pineapple, siraitia grosvenorii and cranberry are directly adopted to hydrolyze egg white to prepare the albumin peptide beverage, the beverage is not concentrated into powder and then compounded, other chemical proteases and preservatives are not added, short peptides with activity can be generated through hydrolysis, and the beverage is closer to human body nutritional requirements and nutritional ingredient proportion requirements, is beneficial to promoting digestion and absorption of the body, reduces allergic reaction of the human body to the egg white, can increase the content of plasma albumin and total protein, is used for daily and clinical protein nutritional supplements, and is simple in production process, low in equipment difficulty and good in product taste, and rapid, complete and efficient industrial production can be realized.