Benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase, its preparation method and its purpose

A technology of bonded silica gel and benzyl nitrogen bridge, which is applied in the field of benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica gel stationary phase and its preparation, achieves simple and convenient preparation method, low preparation cost, High bonding effect

Inactive Publication Date: 2012-06-13
ZHENGZHOU UNIV
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The introduction of aromatic heterocycles and bridging heteroatoms provides new chemical structures and properties for this new ty

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase, its preparation method and its purpose
  • Benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase, its preparation method and its purpose
  • Benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase, its preparation method and its purpose

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0032] Two, the preparation method of benzyl bridged calix [2] arene [2] triazine bonded silica gel stationary phase of the present invention, comprises the following steps,

[0033] 1. Activated silica gel:

[0034] Weigh a certain amount of porous silica gel and immerse it in hydrochloric acid aqueous solution (the volume ratio of hydrochloric acid and water is 1:3), the ratio of silica gel weight (g) to hydrochloric acid volume (ml) is 1:15-1:20. Soak for 12 hours, reflux for 24 hours under magnetic stirring to remove metal ions, then filter with a G5 sand core funnel, rinse repeatedly with double distilled water until neutral, finally wash twice with acetone, and dry at 160°C for 10 hours to remove Remove the surface solvent and water to obtain activated silica gel with evenly distributed hydroxyl groups on the surface, and store it in a desiccator for later use.

[0035] 2. Preparation of aminopropyl silica gel:

[0036] with N 2 Introductory tube, condenser tube, CaCl...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Specific surface areaaaaaaaaaaa
Login to view more

Abstract

The invention discloses a benzyl nitrogen bridged calix [2] arene [2] triazine bonded silica stationary phase, its preparation method and its purpose. The preparation method comprises the following steps: a continuous solid-liquid reaction is used, 3-aminopropyltriethoxysilane silica and tetraazacalix[2]arene[2]triazineN2 is subjected to the reflux reaction under the temperature of 130 DEG C, tetraazacalix[2]arene[2]triazine bonded silica is prepared, then active hydrogen atoms are provided on the benzyl-substituted tetraazacalix[2]arene[2]triazine, and the benzyl nitrogen bridged calix[2]arene[2]triazine bonded silica stationary phase is prepared. The synthesized calixarene bonded stationary phase has the advantages of simple method, high bonding amount, stable bonding layer, low preparation cost, wide application field of preparation method and the like. possesses a traditional ODS reversed phase mode, and can provide a plurality of action sites of hydrogen bond action, Pi-Pi actionand the like, and provides separation possibility for substances which are difficult to separate.

Description

technical field [0001] The invention relates to a separation material, in particular to a benzyl nitrogen-bridged calix[2]arene[2]triazine bonded silica gel stationary phase, a preparation method and application thereof. Background technique [0002] High performance liquid chromatography plays a pivotal role in modern separation analysis. It is widely used in various fields such as chemistry, medicine, life science and environmental science, and has become an indispensable research method. Separation systems are becoming more and more complex, especially the analysis of actual samples puts forward higher requirements for chromatographic techniques, especially chromatographic stationary phases. At present, there are many kinds of commercially available silica gel and modified silica gel, among which octadecyl bonded silica gel (ODS) as the representative reversed-phase chromatographic stationary phase can no longer meet the requirements of separation and analysis. Therefor...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01J20/286B01J20/30
Inventor 赵文杰张书胜汤超常红王彩娟胡锴吴养洁
Owner ZHENGZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap