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Chinese medicinal compound capable of eliminating drug resistance of escherichia coli, as well as preparation method and application thereof

A technology of Escherichia coli and drug resistance, which is applied in the field of traditional Chinese medicine compound and its preparation, can solve the problems of reduced antibiotic treatment effect, increased dosage, and drug-resistant bacteria infecting humans, and achieves the effect of weakening bacterial drug resistance

Active Publication Date: 2012-07-25
靖江市城中村投资建设有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to prevent and treat diseases caused by Escherichia coli, antibiotic additives are used in large quantities, resulting in more and more drug-resistant strains carried by animals. Infecting humans with drug-resistant bacteria

Method used

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  • Chinese medicinal compound capable of eliminating drug resistance of escherichia coli, as well as preparation method and application thereof
  • Chinese medicinal compound capable of eliminating drug resistance of escherichia coli, as well as preparation method and application thereof
  • Chinese medicinal compound capable of eliminating drug resistance of escherichia coli, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] A traditional Chinese medicine compound capable of eliminating drug resistance of Escherichia coli, comprising the following components in parts by weight: 10 parts of honeysuckle, 10 parts of Radix Radix, 10 parts of Scutellaria baicalensis, 8-10 parts of Fangfeng, 10 parts of gardenia, 10 parts of chrysanthemum, 10 parts of buffalo horn, 10 parts of bovine and sheep cholic acid, and 10 parts of mulberry leaves.

[0015] Preparation method: crush honeysuckle, isatis root, scutellaria baicalensis, windproof, gardenia, chrysanthemum, buffalo horn, bovine and sheep cholic acid and mulberry leaves, mix, add 4 times the weight of water, decoct for 40 minutes, and then filter residue and Filtrate is separated; Add 3 times the weight of water to the above filter residue, decoct again for 30 minutes, then separate the filter residue and filtrate; The filtrate was separated; all the filtrates obtained before were combined, vacuum filtered, and evaporated to dryness at a constan...

Embodiment 2

[0017] A traditional Chinese medicine compound capable of eliminating drug resistance of Escherichia coli, comprising the following components in parts by weight: 8 parts of honeysuckle, 8 parts of Radix Radix, 8 parts of Scutellaria baicalensis, 8 parts of Fangfeng, 8 parts of gardenia, 10 parts of chrysanthemum, and buffalo horn 10 parts, 10 parts of bovine and sheep cholic acid, 10 parts of mulberry leaves.

[0018] Preparation method: crush honeysuckle, isatis root, scutellaria baicalensis, windproof, gardenia, chrysanthemum, buffalo horn, bovine goat cholic acid and mulberry leaves, mix, add 5 times the weight of water, decoct for 30 minutes, and then filter residue and The filtrate is separated; water of 4 times the weight is added to the above-mentioned filter residue, decocted for 40 minutes again, and then the filter residue and the filtrate are separated; water of 3 times the weight is added to the obtained filter residue, and decocted for 20 minutes again, and then t...

Embodiment 3

[0020] A traditional Chinese medicine compound capable of eliminating drug resistance of Escherichia coli, comprising the following components in parts by weight: 10 parts of honeysuckle, 10 parts of Radix Radix, 10 parts of Scutellaria baicalensis, 10 parts of Fangfeng, 10 parts of gardenia, 8 parts of chrysanthemum, and buffalo horn 8 parts, 8 parts of bovine and sheep cholic acid, 8 parts of mulberry leaves.

[0021] Preparation method: crush honeysuckle, isatis root, scutellaria baicalensis, windproof, gardenia, chrysanthemum, buffalo horn, bovine goat cholic acid and mulberry leaves, mix, add 3 times the weight of water, decoct for 20 minutes, and then filter residue and The filtrate is separated; add 2 times the weight of water to the above filter residue, decoct for 20 minutes again, then separate the filter residue and the filtrate; add 1 times the weight of water to the obtained filter residue, decoct for 10 minutes again, and then filter the residue and the filtrate ...

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Abstract

The invention discloses a Chinese medicinal compound capable of eliminating drug resistance of Escherichia coli, which comprises the following components in parts by weight: 8 to 10 parts of honeysuckle, 8 to 10 parts of isatis root, 8 to 10 parts of large-flowered skullcap root, 8 to 10 parts of cape jasmine, 8 to 10 parts of chrysanthemum, 8 to 10 parts of buffalo horn, 8 to 10 parts of sodium cholate, and 8 to 10 parts of mulberry leaf. The invention also discloses a preparation method and application of the Chinese medicinal compound. The Chinese medicinal compound has the function of eliminating or weakening the drug resistance of bacteria, and has further popularization value clinically.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine compound capable of eliminating drug resistance of Escherichia coli and its preparation method and application. Background technique [0002] Escherichia coli is a common and harmful bacteria in livestock production. In order to prevent and treat diseases caused by Escherichia coli, antibiotic additives are used in large quantities, resulting in more and more drug-resistant strains carried by animals. Infecting humans with drug-resistant bacteria. Especially in recent years, superbugs with high drug resistance have attracted more and more attention from the international community. [0003] In the past 30 years, many researchers at home and abroad are actively looking for effective methods to eliminate drug-resistant plasmids to reverse bacterial drug resistance. Chinese medicine has a long history in my country,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P31/04A61K31/575A61K35/32
CPCY02A50/30
Inventor 张志成吴镝白小磊戴鼎震陈钟鸣
Owner 靖江市城中村投资建设有限公司