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Medicine composition for treating tumor and preparation method for medicine composition

A composition and drug technology, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc., can solve the problems of serious side effects and easy recurrence of patients

Active Publication Date: 2013-10-23
GUIZHOU SHENQI PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the initial effectiveness of radiotherapy and chemotherapy is high, most patients have severe side effects, are prone to recurrence, and require drug treatment at the same time. Therefore, drug therapy is the most common treatment method

Method used

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  • Medicine composition for treating tumor and preparation method for medicine composition
  • Medicine composition for treating tumor and preparation method for medicine composition
  • Medicine composition for treating tumor and preparation method for medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Composition: leopard frog enzyme 10mg, mannan peptide 10mg

[0056] The preparation process of the injection is as follows: mix the above-mentioned leopard frog enzyme and mannan peptide, add water for injection to 1000ml, filter with a 0.45 μm microporous membrane, stir for 20 minutes to mix evenly, potting, and sterilizing. Injectable preparations.

[0057] Usage and dosage: intravenous injection or intravenous infusion, 10-50ml each time, once a day.

Embodiment 2

[0059] Composition: leopard frog enzyme 5mg, mannan peptide 5mg

[0060] The preparation process is as follows: take the above-mentioned leopard frog enzyme, mannan peptide, 250ml of glycerin, 100g of lactose, and 150g of mannitol, mix evenly, add water for injection to 1000ml, adjust the pH value of the liquid to 7, filter, fill, freeze-dry, that is Freeze-dried powder. The freeze-drying process is as follows: the filled vials are half-stoppered and sent to a freeze dryer, slowly frozen to below -15°C, vacuumed to 5-10Pa, and controlled to heat up at a rate of no more than 4°C / h for sublimation. After 10 hours of sublimation, set the shelf temperature to 20°C for the second drying. When the product temperature is close to the shelf temperature, dry at a constant temperature for 0.5-1 hour and then fully press the plug.

[0061] Usage and dosage: intravenous injection or intravenous drip, 0.5-5mg each time, once a day.

Embodiment 3

[0063] Composition: leopard frog enzyme 15mg, mannan peptide 20mg

[0064] The preparation process is as follows: mix the above leopard frog enzyme and mannan peptide, add 10Kg of sodium chloride to mix, add water for injection to 1000L, adjust the pH to 6, filter with a 0.22μm microporous membrane, stir for 20 minutes to mix evenly, Subpackage and sterilize to obtain a large-volume injection.

[0065] Usage and dosage: intravenous injection or intravenous drip, 500-1000ml each time, once a day.

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Abstract

The invention discloses a medicine composition for treating tumor. The medicine composition is prepared from ranpirnase, mannatide and auxiliary materials. The medicine composition not only can be used for improving the immunologic function of the organism but also can be used for directly restraining and killing tumor cells and is obvious in effect, and a gospel is brought to tumor patients.

Description

field of invention [0001] The invention relates to a pharmaceutical composition for treating tumors and a preparation method thereof, belonging to the field of pharmaceutical technology. technical background [0002] For a long time, tumors have been regarded as "incurable diseases", especially advanced tumors, people are even talking about its discoloration. There are many reasons for this notion. First of all, due to the low immunity of patients with advanced tumors, the rapidly proliferating tumor cells will aggravate the decline in the immune function of tumor patients after consuming a large amount of nutrients, forming a vicious circle, resulting in high fever, fatigue, anorexia, progressive weight loss, etc. symptoms until bedridden. [0003] In recent years, the incidence of lung cancer, primary liver cancer, colorectal cancer, and gynecological malignant tumors has increased year by year, and has become the most common malignant tumor that seriously endangers huma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/46A61K38/16A61P35/00
Inventor 张芝庭张涛涛何莉华
Owner GUIZHOU SHENQI PHARMA RES INST